Blar i Institutt for klinisk og molekylær medisin på tittel
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Exploring endoplasmic reticulum stress responses and senescence upon infection with respiratory syncytial virus
(Master thesis, 2024)Respiratorisk syncytialt-virus (RS-virus) er et av de vanligste årsakene til akutt respiratorisk infeksjon hos nyfødte og infeksjonen påvirker cellulære mekanismer i vertscellene. Tidligere studier har vist at RS-virus kan ... -
Exploring lifestyle and risk in preventing type 2 diabetes-a nested qualitative study of older participants in a lifestyle intervention program (VEND-RISK)
(Journal article; Peer reviewed, 2016)Background: Lifestyle intervention may reduce the development of type 2 diabetes among high-risk individuals. The aim of this study was to explore how older adults perceived their own lifestyle and being at increased ... -
Exploring responses of type I and type III interferons in human macrophages
(Master thesis, 2021)Interferons are antiviral cytokines induced during viral infection. Type I and III IFNs are thought to share some of the same transcriptional outputs, yet some biological responses are distinct. IFN-λ receptor (IFNLR1) ... -
Exploring the cardioprotective effects of miR-210 in doxorubicin-treated cardiomyocytes
(Master thesis, 2024)Bakgrunn: Doxorubicin (DOX) er et mye brukt kreftlegemiddel. På grunn av betydelig kardiotoksisitet må den kumulative dosen kontrolleres nøye. Studier har vist at mikroRNA-210 (miR-210) kan ha en beskyttende effekt på ... -
Exploring the cGAS-STING axis and DNA damage after infection with respiratory syncytial virus
(Master thesis, 2024)Cyclic GMP-AMP synthase (cGAS) er primært kjent som en cytosolisk DNA-sensor, som aktiverer medfødte immunresponser gjennom stimulator of interferon genes (STING). cGAS har nylig også blitt funnet lokalisert til kjernen i ... -
Exploring the Crosstalk Between RIG-I-mediated Signalling and β-catenin
(Master thesis, 2011)Hepatocellular carcinoma (HCC) is the most common type of liver cancer and among the leading causes of cancer related death worldwide. Hepatocarcinogenesis has been attributed to chronic viral infection and alterations in ... -
Exploring the diagnostic potential of adding T2 dependence in diffusion-weighted MR imaging of the prostate
(Peer reviewed; Journal article, 2021)Background: Magnetic resonance imaging (MRI) is essential in the detection and staging of prostate cancer. However, improved tools to distinguish between low-risk and high-risk cancer are needed in order to select the ... -
Exploring the fungal microbiome in breast cancer patients
(Master thesis, 2021)The role of the Fungal Microbiome in the human body has been gradually revealed. Its presence in the gut, although scarce in comparison to bacteria, is now associated with several physiologic functions such as immune ... -
Exploring the hepatitis C virus encoded protease NS3/4A in relation to Autophagy
(Master thesis, 2011)Autophagy is an evolutionarily conserved intracellular bulk degradation system essential for the cell homeostasis. In addition, autophagy is emerging as a central component in viral host defense. Many pathogens have evolved ... -
Exploring the relationship between bone density and severity of distal radius fragility fracture in women
(Journal article; Peer reviewed, 2014)Background Bone mineral density (BMD) has been shown to be a consistent and independent risk factor for distal radius fracture. Inconsistent data have been reported on the association between BMD and severity of distal ... -
Exploring the role of IKKε during hepatitis C virus infection with focus on lipid accumulation
(Master thesis, 2020)Hepatitis C virus (HCV) targets the hepatocytes in the liver. HCV develops a chronic infection in 85% of infected patients which develops over decades and have different outcomes, for example hepatic steatosis (accumulation ... -
Exploring the role of miR-210 on mitochondrial respiration in doxorubicin-treated human AC16 cardiomyocytes
(Master thesis, 2024)Doxorubicin (Dox) er en potent og bredt anvendt legemiddelbehandling av kreft. Dens kliniske bruk er forbundet med doseavhengig kardiomyopati, som kan medføre til kongestiv hjertesvikt. Mekanismene som er ansvarlige for ... -
Exploring the role of the immunoglobulin-like receptor SLAMF1 in infection with human metapneumovirus
(Master thesis, 2021)Humant metapneumovirus (HMPV) er en ledende årsak til nedre luftveisinfeksjon. Generelt finnes det lite informasjon om hvordan HMPV entrer (infiserer), etablerer replikasjon og induserer immunresponser. Nylige funn fra en ... -
Exploring the role of TLR8 as a sensor in bacterial infections
(Doctoral theses at NTNU;2019:382, Doctoral thesis, 2019) -
Exploring the viability of measuring zinc and prostate-specific antigen in urine as a diagnostic tool for prostate cancer
(Master thesis, 2021)Bakgrunn: Nåværende metoder for å diagnostisere prostatakreft benytter seg av inngripende biopsier, som kan føre til komplikasjoner som infeksjon og død. Ikke-inngripende metoder benytter seg av PSA målinger, som ofte er ... -
Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice
(Journal article; Peer reviewed, 2015)Type 1 diabetes mellitus (T1DM) is an autoimmune destruction of insulin producing pancreatic beta-cells due to a genetic predisposition and can be triggered by environmental factors. We have previously shown that bisphenol ... -
Express Team-Based Learning (eTBL): A Time-Efficient TBL Approach in Neuroradiology
(Peer reviewed; Journal article, 2019)Rationale and Objectives Team-based learning (TBL) is a student-centred, teacher-directed instructional method that promotes active learning. The application phase of TBL stimulates group discussion and critical thinking, ... -
Expression and clinical significance of the proliferation marker minichromosome maintenance protein 2 (Mcm2) in diffuse astrocytomas WHO grade II
(Journal article; Peer reviewed, 2013)Background The WHO classification system for astrocytomas is not considered optimal, mainly because of the subjective assessment of the histopathological features. Few prognostic variables have been found that stratify ... -
Expression and clinical value of EGFR in human meningiomas
(Journal article; Peer reviewed, 2017)Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal ... -
Expression and function of FSTL5 in multiple myeloma cells
(Master thesis, 2021)Multiple myeloma (MM) is an incurable cancer arising in the antibody-producing plasma cells that are located in the bone marrow. The malignant cells disturb the balance between bone forming and bone degrading cells, leading ...