Browsing Institutt for klinisk og molekylær medisin by Issue Date
Now showing items 1-20 of 1998
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Low fat, low lactose diet used as prophylactic treatment of acute intestinal reactions during pelvic radiotherapy. A prospective randomised study
(Dissertations at the Faculty of Medicine, 0805-7680; 203, Doctoral thesis, 2002)Purpose. The main aim of the present study was to evaluate the effect of a low fat, low lactose diet on acute and late gastrointestinal side effects of pelvic radiotherapy. We also wanted to evaluate if such a treatment ... -
Preeclampsia - maternal risk factors and fetal growth
(Dissertations at the Faculty of Medicine; 212, Doctoral thesis, 2002)Preeclampsia is a complex and variable maternal disturbance that ranges from a dramatic onset at early gestation to slowly developing symptoms towards term. Hypertension and renal involvement with proteinuria are cardinal ... -
Centralization of primary surgery for ovarian cancer: Feasibility and impact on survival
(Dissertations at the Faculty of Medicine, 0805-7680; 223, Doctoral thesis, 2003)The general aim of the thesis was to gain more epidemiological knowledge of ovarian cancer by studying the feasibility and effect of centralized primary surgery on survival for ovarian cancer. The individual papers had the ... -
Macromolecular maintenance in human cells : repair of uracil in DNA and methylations in DNA and RNA
(Dissertations at the Faculty of Medicine, 0805-7680; 243, Doctoral thesis, 2004)In all known organisms, except some viruses, genetic information is contained in the form of DNA. Although genetically relatively stable, DNA is subject to continuous damage from the external- and cellular environment. ... -
Gastric cancer in Japanese cotton rats
(Doktoravhandlinger ved NTNU, 1503-8181; 2004:125, Doctoral thesis, 2004)The role of gastrin and the enterochromaffin-like (ECL) cell in human gastric carcinogenesis is not fully understood. There are numerous animal models that can be useful when studying this process. One such model is the ... -
Risk assessment on the use of triclosan in cosmetics. Prepared by the Scientific Committee in cooperation with the Panel on Biological Hazards and the Panel on Food Additives, Flavourings, Processing Aids, Materials in contact with Food and Cosmetics
(VKM Report;, Research report, 2005)Triclosan is a widely used biocide. It is included in many contemporary consumer- and professional health-care products, particularly oral and dermal products, but also in household items including plastics, textiles and ... -
Multiple myeloma : the interplay between malignant plasma cells and the bonemarrow microenvironment
(Dissertations at the Faculty of Medicine, 0805-7680; 2006:26272, Doctoral thesis, 2006)The overall objective of this work was to study how myeloma cells influence the bone marrow microenvironment in which they reside, focusing on the cells that resorb or synthesize bone. More specifically we wanted to ... -
Effects of bone morphogenetic proteins, hepatocyte growthfactor and interleukin-21 in multiple myeloma
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:4, Doctoral thesis, 2006)The studies presented in this thesis answer some questions, but also raise new questions which should be explored in future studies. The bone marrow microenvironment is a complex system, and is difficult to study in vitro. ... -
Strategies in Rectal Cancer Treatment - Focus on early rectal cancer and the influence of age on prognosis
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:43, Doctoral thesis, 2006) -
Gene expression studies in gastrointestinal pathophysiology and neoplasia
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:89, Doctoral thesis, 2006) -
Detection of congenital heart defects in a non-selected population of 42,381 fetuses
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:112, Doctoral thesis, 2006)Bakgrunn Siden 1986 har alle gravide i Norge fått tilbud om en ultralydundersøkelse ved 18 uker i svangerskapet. En av hensiktene med undersøkelsen er å oppdage sykdom hos fosteret for å optimalisere oppfølging, tidspunkt ... -
Lack of patients? a hypothesis for understanding discrepancies between hospital resources and productivity
(Journal article; Peer reviewed, 2006)Background: Despite a substantial increase in hospital resources, increased hospital admissions and out-patient visits, long waiting lists have been a significant problem in Norwegian health care. A detailed analysis of ... -
Human Base Excision Repair for Preservation of Genomic Stability
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:56, Doctoral thesis, 2006) -
Alginate capsules as bioreactors for cell therapy
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:24, Doctoral thesis, 2006) -
Irritable bowel syndrome in Norway
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:83, Doctoral thesis, 2006) -
Improving treatment in patients with lung cancer: Results from two multicentre randomised studies
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:42, Doctoral thesis, 2006) -
Physical activity and exercise interventions in cancer patients
(Dissertations at the Faculty of Medicine, 0805-7680; 279, Doctoral thesis, 2006) -
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
(Journal article; Peer reviewed, 2006)Immune responses are initiated when molecules of microbial origin are sensed by the Toll‐like receptors (TLRs). We now report the identification of essential molecular components for the trafficking of the lipopolysaccharide ... -
No association between chronic musculoskeletal complaints and Val158Met polymorphism in the Catechol-O-methyltransferase gene. The HUNT Study
(Journal article; Peer reviewed, 2006-05-04)Background: The Catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met, that has been found to influence human pain perception. In one study fibromyalgia was less likely among those with ... -
Fatigue in cancer treatment - assessment, course and etiology
(Doktoravhandlinger ved NTNU, 1503-8181; 2007:138, Doctoral thesis, 2007)Aims. The major aims of the present work were to increase the understanding of cancer related fatigue with respect to assessment methodology, frequency and possible etiology. The validity of two fatigue instruments was ...