Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1396-1415 of 1899
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Quality assessment of structure and language elements of written responses given by seven Scandinavian drug information centres.
(Journal article; Peer reviewed, 2017)Purpose The aim of this study was to identify structure and language elements affecting the quality of responses from Scandinavian drug information centres (DICs). Methods Six different fictitious drug-related queries ... -
Quality of life and symptom intensity over time in people with cancer receiving palliative care: Results from the international European Palliative Care Cancer Symptom study
(Journal article; Peer reviewed, 2019)Background People with advanced cancer experience multiple symptoms during their illness trajectory, which can fluctuate in intensity. Aim To describe the course of self-reported quality of life, emotional functioning, ... -
Quality of life in older dialysis patients : influencing factors and research challenges
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:48, Doctoral thesis, 2013) -
Quality or equality? The Norwegian experience with medical monopolies
(Journal article; Peer reviewed, 2007)Background: In order to maintain both quality and efficiency of health services in a small country with a scattered population, Norway established a monopoly system for 38 highly specialized medical services. The ... -
Quand le présent dépasse les bornes: Une analyse à la croisée des approches linguistiques et cognitives
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:155, Doctoral thesis, 2011) -
Quantification and Qualitative Effects of Different PEGylations on Poly(butyl cyanoacrylate) Nanoparticles
(Journal article, 2017)Protein adsorption on nanoparticles (NPs) used in nanomedicine leads to opsonization and activation of the complement system in blood, which substantially reduces the blood circulation time of NPs. The most commonly used ... -
Quantification of doxorubicin in mouse serum and tumor tissue by liquid chromatography tandem mass spectrometry: An application in an in vivo study with murine prostate cancer xenograft tumor and ultrasound-sensitive liposomal doxorubicin
(Master thesis, 2013)Non-specificity and systemic toxicity are major challenges with cancer chemotherapy. This situation is further complicated by abnormality of tumor microenvironment that presents potential barriers to drug delivery. These ... -
Quantifying the impact of genes on body mass index during the obesity epidemic: Longitudinal findings from the HUNT Study
(Peer reviewed; Journal article, 2019)Objectives: To study the trajectories of body mass index (BMI) in Norway over five decades and to assess the differential influence of the obesogenic environment on BMI according to genetic predisposition. Design: ... -
Quantifying tumour vascularity in non-luminal breast cancers
(Journal article; Peer reviewed, 2017)Aims Microvessel density (MVD), proliferating MVD (pMVD) and vascular proliferation index (VPI) are methods used to quantify tumour vascularity in histopathological sections. In this study, we assessed MVD, pMVD and VPI ... -
Quantitative analysis of binding and internalization of αvβ3 integrin-targeted nanoemulsions by human endothelial cells: In vitro
(Master thesis, 2016)The purpose of this master thesis was to quantitatively study the binding and internalization of αvβ3 integrin-targeted RGD-conjugated nanoemulsions (RGD-NE) by human umbilical vein endothelial cells (HUVEC) in vitro. The ... -
Quantitative texture analysis in the prediction of IDH status in low-grade gliomas
(Journal article; Peer reviewed, 2017)Objectives Molecular markers provide valuable information about treatment response and prognosis in patients with low-grade gliomas (LGG). In order to make this important information available prior to surgery the aim of ... -
R2* Relaxation Affects Pharmacokinetic Analysis of Dynamic Contrast-Enhanced MRI in Cancer and Underestimates Treatment Response at 7 T
(Journal article, 2019)Effective transverse relaxivity of gadolinium-based contrast agents is often neglected in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Here, we assess time and tissue dependence of R2* enhancement and ... -
Rab11a GTPase controls Toll-like receptor 4 trafficking and signaling
(Master thesis, 2010)Rab GTPases are involved in controlling the endosomal pathway, and we have developed an expression system allowing us to study the expression and trafficking of these molecules in live cells. Toll-like receptor 4 (TLR4) ... -
Radiological and epidemiological aspects of mammographic screening
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:298, Doctoral thesis, 2013)Breast cancer is the most frequent cancer and the most frequent cause of cancer death in women worldwide. Service screening programs have been implemented in many countries in the western world, with the intention to reduce ... -
Radiologisk vekstmåling av glioblastomer
(Master thesis, 2016)Bakgrunn: Anbefalt metode for bedømming av vekst av glioblastomer er i dag todimensjonale mål i henhold til RANO-kriteriene. En viktig svakhet ved denne metoden er at den bruker todimensjonale mål på en irregulær tredimensjonal ... -
Radiotherapy for prostate cancer – Does daily image guidance with tighter margins improve patient reported outcomes compared to weekly orthogonal verified irradiation? Results from a randomized controlled trial
(Journal article; Peer reviewed, 2018)Background Novel cancer drugs are subject to strict scientific evaluation of safety and efficacy and usually undergo a cost effectiveness analysis before approval for use in clinical practice. For new techniques in ... -
Radiotherapy in anal carcinoma and prostate cancer
(Doktoravhandlinger ved NTNU, 1503-8181; 2008:318, Doctoral thesis, 2008)Moderne kreftbehandling har medført at flere pasienter blir friske og flere lever i mange år etter diagnose. Behandlingen består ofte av en kombinasjon av flere behandlingsformer, hvilket medfører en økt risiko for ... -
Radiotherapy in patients with bone metastases; treatment schedules and evaluations
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:162, Doctoral thesis, 2014)Strålebehandling til pasienter med spredning til skjelett; strålefraksjoner og evalueringer Spredning av kreft til skjelett (skjelettmetastaser) den vanligste årsaken til krefsmerte. Strålebehandling gir en effektiv ... -
Raised serum levels of syndecan-1 (CD138), in a case of acute idiopathic systemic capillary leak syndrome (SCLS) (Clarkson's disease)
(Journal article; Peer reviewed, 2018)BACKGROUND: Systemic capillary leak syndrome (SCLS) (Clarkson’s disease) is a rare disorder of unknown etiology, characterized by transient episodes of hypotension, and the microvascular leak of fluids into the peripheral ... -
Randomized clinical trial of topical tranexamic acid after reduction mammoplasty
(Journal article; Peer reviewed, 2015)Background The antifibrinolytic drug tranexamic acid is currently being rediscovered for both trauma and major surgery. Intravenous administration reduces the need for blood transfusion and blood loss by about one-third, ...