Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 224-243 of 1966
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C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
(Journal article; Peer reviewed, 2018)The chemokine C-C motif ligand 20 (CCL20) is increased in the colonic mucosa during active inflammatory bowel disease (IBD) and can be found both in the epithelium and immune cells in the lamina propria. The present study ... -
c-Myb Binding Sites in Haematopoietic Chromatin Landscapes
(Journal article, 2015)Strict control of tissue-specific gene expression plays a pivotal role during lineage commit- ment. The transcription factor c-Myb has an essential role in adult haematopoiesis and func- tions as an oncogene when rearranged ... -
Caesarean birth experiences. A qualitative study from Sierra Leone.
(Journal article; Peer reviewed, 2019)Background Positive birth experiences lead to better postnatal functioning, and influence mode of delivery choice for subsequent pregnancies. Healthcare workers can influence the birth experience through relevant support ... -
Caesarean section performed by medical doctors and associate clinicians in Sierra Leone
(Journal article; Peer reviewed, 2019)Background Many countries lack sufficient medical doctors to provide safe and affordable surgical and emergency obstetric care. Task‐sharing with associate clinicians (ACs) has been suggested to fill this gap. The aim ... -
Can oxytocin augmentation modify the risk of epidural analgesia by maternal age in cesarean sections?
(Journal article; Peer reviewed, 2018)Introduction Maternal age is an established risk factor for cesarean section; epidural analgesia and oxytocin augmentation may modify this association. We investigated the effects and interactions of oxytocin augmentation, ... -
Can spectral-spatial image segmentation be used to discriminate experimental burn wounds?
(Journal article; Peer reviewed, 2016)Hyperspectral imaging (HSI) is a noncontact and noninvasive optical modality emerging the field of medical research. The goal of this study was to determine the ability of HSI and image segmentation to discriminate burn ... -
Can ultrasound predict labor outcome in operative vaginal deliveries?
(Doctoral theses at NTNU;2020:183, Doctoral thesis, 2020) -
Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?
(Journal article; Peer reviewed, 2015)Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this hypothesis-generating, ... -
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling
(Journal article; Peer reviewed, 2017)The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ... -
Cancer Cachexia: Classification, Pathophysiology and Treatment
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:49, Doctoral thesis, 2014)Cachexia is a very common condition in patients with cancer and it has detrimental effects on both mortality and morbidity. Cachexia is characterized by progressive unintentional loss of muscle mass, with or without loss ... -
Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial
(Journal article; Peer reviewed, 2018)Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a ... -
Cancer pain assessment, classification and patient reported outcomes in the evaluation of treatment effect
(Doctoral theses at NTNU;2016:328, Doctoral thesis, 2016)Pain is common in patients with cancer and it has a strong impact on quality of life. Despite the development of guidelines, cancer pain treatment is suboptimal. This is often due to lack of efficient, standardized and ... -
Cancer pain classification
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:112, Doctoral thesis, 2012)Klassifikasjon av kreftsmerte Kreftsmerte – hva skal et fremtidig klassifikasjonssystem inneholde? Smerte er et subjektivt, sammensatt og plagsomt symptom som forekommer hyppig hos kreftpasienter. Til tross for eksisterende ... -
Cancer pain – clinical studies on prevalence and treatment with nasal fentanyl
(Doctoral thesis at NTNU;2016:81, Doctoral thesis, 2016)Summary in English: Pain is one of the most feared symptoms among cancer patients. Studies show that about 50% of all cancer patients experience pain and these numbers are increasing for patients with advanced disease. ... -
Cancer patients' knowledge about their disease and treatment before, during and after treatment: a prospective, longitudinal study
(Journal article; Peer reviewed, 2018)Background Knowledge about disease and treatment is necessary before patients can consent to treatment. One of the few established instruments for evaluating whether sufficient information has been provided, is the EORTC ... -
Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study
(Journal article; Peer reviewed, 2019)Background Because of the potential mutagenic effects of chemo- and radiotherapy, there is concern regarding increased risk of congenital malformations (CMs) among children of fathers with cancer. Previous register studies ... -
Carbon nanofibers have IgE adjuvant capacity but are less potent than nanotubes in promoting allergic airway responses
(Journal article; Peer reviewed, 2013)There is a growing concern for the possible health impact of nanoparticles. The main objective of this study was to investigate the allergy-promoting capacity of four different carbon nanofiber (CNF) samples in an injection ... -
Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity
(Journal article; Peer reviewed, 2019)Objective Patients with rheumatoid arthritis (RA) suffer from more cardiovascular disease (CVD), and develop cardiovascular risk factors at an earlier age than the general population. Cardiorespiratory fitness (CRF) is an ... -
Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: The population-based Nord-Trøndelag health study (HUNT)
(Journal article; Peer reviewed, 2014)with individuals without RA or osteoarthritis at both times (n = 33,567). Results Female gender, age, smoking, body mass index, and history of previous CV disease were associated with self-reported incident RA (previous ... -
Cardiovascular health and the modifiable burden of incident myocardial infarction: The Tromsø Study
(Peer reviewed; Journal article, 2015)Background:The American Heart Association has proposed an impact goal for the year 2020 to improve cardiovascular health by 20%. The objectives of the study were to assess the association between the proposed cardiovascular ...