Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1145-1164 av 3589
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Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN
(Peer reviewed; Journal article, 2020)Objective We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. Methods We used multiple in vivo and in vitro methods to explore the mechanisms ... -
Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain
(Peer reviewed; Journal article, 2023)Background Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer's disease (AD). These beneficial effects may be partly mediated by blood-borne factors. ... -
Existing data sources in clinical epidemiology: The Scandinavian Thrombosis and Cancer Cohort
(Peer reviewed; Journal article, 2015)Background: Although venous thromboembolism (VTE) is a known common complication in cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in the general population. The Scandinavian ... -
Exome chip analyses in adult attention deficit hyperactivity disorder
(Journal article; Peer reviewed, 2016)Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ... -
Expanding the activity spectrum of antiviral agents
(Peer reviewed; Journal article, 2019) -
Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities
(Peer reviewed; Journal article, 2023)Gene regulation plays a critical role in the cellular processes that underlie human health and disease. The regulatory relationship between transcription factors (TFs), key regulators of gene expression, and their target ... -
Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma
(Journal article; Peer reviewed, 2018)Novel predictive tools for clear cell renal cell carcinoma (ccRCC) are urgently needed. MicroRNAs (miRNAs) have been increasingly investigated for their predictive value, and formalin-fixed paraffin-embedded biopsy archives ... -
Experiences among school personnel and school nurses on educational adaptations for students with CFS/ME: A qualitative interview study
(Peer reviewed; Journal article, 2021)Introduction: Chronic fatigue syndrome (CFS/ME) is a disabling disease severely impacting school attendance, education, and social life in young students. Uncertainties surrounding CFS/ME etiology may impact the interpretation ... -
Experiences and perceptions of foreign-language customers on medication information received in the pharmacy – a focus group study
(Peer reviewed; Journal article, 2021)Background In pharmacies, communication is essential for providing information about medicine and counselling customers on the correct use of medications. Previous studies have described pharmacists experiencing language ... -
Experiences of childbirth care among immigrant and non-immigrant women: a cross-sectional questionnaire study from a hospital in Norway
(Peer reviewed; Journal article, 2023)Background Immigrant women have higher risks for poor pregnancy outcomes and unsatisfactory birth experiences than the general population. The mechanisms behind these associations remain largely unknown, but they may ... -
Experimental-Computational Approaches to Identify Synergistic Effects of Anti-Cancer Drugs
(Doctoral theses at NTNU;2019:384, Doctoral thesis, 2019)Drug combinations are hoped to improve treatment response to anti-cancer drugs by targeting the cancers vulnerabilities at diverse trajectories. With a large number of approved agents of chemotherapeutic and targeted ... -
Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data.
(Journal article; Peer reviewed, 2019)Maximal expiratory airflow peaks early in the third decade of life, then gradually declines with age. The pattern of airflow through adulthood for individuals born very preterm (at <32 weeks’ gestation) or ... -
Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway
(Peer reviewed; Journal article, 2022)Previous studies indicate sex differences in incidence and severity of bloodstream infections (BSI). We examined the effect of sex on risk of BSI, BSI mortality, and BSI caused by the most common infecting bacteria. Using ... -
Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey
(Peer reviewed; Journal article, 2015)Objectives The International Cancer Benchmarking Partnership (ICBP) is a collaboration between 6 countries and 12 jurisdictions with similar primary care-led health services. This study investigates primary care physician ... -
Exploration of 27 plasma immune markers: A cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons
(Journal article; Peer reviewed, 2018)Background The prevalence of major depression (MD) according to population studies is the same for old (65 years and older) and younger adults. In contrast, an elevated proportion of old MD patients are hospitalized ... -
Exploring autophagy and its components in relation to the of the innate immune system
(Master thesis, 2009) -
Exploring Biomarkers for Weight Loss in Cancer Cachexia: The Prognostic Value of Serum sP-selectin, Activin A and Autophagy-stimulatory Activity
(Master thesis, 2012)Cancer cachexia is an extremely devastating wasting syndrome that adversely influences treatment response, quality of life and survival rates of patients. It involves severe metabolic imbalance resulting in progressive ... -
Exploring cell death mechanisms upon infection with respiratory syncytial virus
(Master thesis, 2024)Respiratorisk syncytialt virus (RSV) utgjør en betydelig helseutfordring, og rammer spesielt eldre, immunkompromitterte individer og små barn. Akutt lungeskade indusert av virus er knyttet til celledød en frigjøring av ... -
Exploring Dietary Intake in Adults with Severe Obesity and Associations with the FTO rs9939609 Genotypes
(Peer reviewed; Journal article, 2023)Background Few have studied the associations between rs9939609 genotypes in the obesity candidate locus FTO and energy and nutrient intakes and meal frequencies in adults with severe obesity. We are unaware of studies ... -
Exploring drug resistance mechanisms in Multiple Myeloma - Focusing on the role of immunoglobulin kappa light chain and protein secretion
(Master thesis, 2019)Multiple myeloma (MM) is a type of cancer arising in the bone marrow affecting the immunoglobulin (Ig) producing plasma cells. This causes an uncontrolled proliferation of a single plasma cell clone and an overproduction ...