Institutt for klinisk og molekylær medisin
Recent Submissions
-
Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report
(Peer reviewed; Journal article, 2021)Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ... -
Quality of life in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—the randomized nordic9-study
(Peer reviewed; Journal article, 2021)Bowel cancer is one of the leading cancer-types in both sexes worldwide. Despite that most new cases and deaths occur in people aged 70 years or older, few clinical trials have investigated the best way to administer ... -
Spiritual quality of life in family carers of patients with advanced cancer—a cross-sectional study
(Peer reviewed; Journal article, 2021)Purpose Caring affects carers’ psychological and physical health, mortality, and quality of life (QoL) negatively. Lower spiritual QoL is associated with anxiety and depression, but the spiritual dimension is rarely ... -
Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications
(Peer reviewed; Journal article, 2021)Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility, easy processability, transparency, non-toxicity, and reasonable mechanical properties ... -
Reduced LDL-Cholesterol and Reduced Total Cholesterol as Potential Indicators of Early Cancer in Male Treatment-Naïve Cancer Patients With Pre-cachexia and Cachexia
(Peer reviewed; Journal article, 2020)Cancer cachexia is characterized by the impairment of glucose and lipid homeostasis, the acceleration of processes promoting the mobilization of energy-rich compounds (e.g., insulin resistance, gluconeogenesis, and lipolysis) ... -
Previous life experiences and social relations affecting individuals wish for support when establishing healthy habits – a qualitative study of Norwegian Healthy Life Centre participants
(Peer reviewed; Journal article, 2021)Background: Interventions to reduce and prevent overweight, obesity and T2D has been advocated worldwide. In Norway, Healthy Life Centres have been established to help individuals to reduce and prevent diseases, offering ... -
Secreted wnt antagonists in scrub typhus
(Peer reviewed; Journal article, 2021)Background The mechanisms that control local and systemic inflammation in scrub typhus have only been partially elucidated. The wingless (Wnt) signaling pathways are emerging as important regulators of inflammation and ... -
Epigenetic mapping of the somatotropic axis in Nile tilapia reveals differential DNA hydroxymethylation marks associated with growth
(Peer reviewed; Journal article, 2021)In vertebrates, the somatotropic axis comprising the pituitary gland, liver and muscle plays a major role in myogenesis. Its output in terms of muscle growth is highly affected by nutritional and environmental cues, and ... -
Phosphatidylethanol as blood biomarker of alcohol consumption in early pregnancy: An observational study in 4067 pregnant women
(Peer reviewed; Journal article, 2021)Background: The teratogenic effects of alcohol are well documented, but there is a lack of screening methods to detect alcohol use during pregnancy. Phosphatidylethanol 16:0/18:1 (PEth) is a specific and sensitive biomarker ... -
Hemorrhagic shock induces a rapid transcriptomic shift of the immune balance in leukocytes after experimental multiple injury
(Peer reviewed; Journal article, 2021) -
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
(Peer reviewed; Journal article, 2021)We have investigated the biodistribution and tumor macrophage infiltration after intravenous injection of the poly(alkyl cyanoacrylate) nanoparticles (NPs): PEBCA (poly(2-ethyl-butyl cyanoacrylate), PBCA (poly(n-butyl ... -
Microbiota in inflammatory bowel disease
(Doctoral theses at NTNU;2021:86, Doctoral thesis, 2021) -
High performance and toxicity assessment of Ta3N5 nanotubes for photoelectrochemical water splitting
(Peer reviewed; Journal article, 2020)In this work, Co-based cocatalysts are electrodeposited on mesoporous Ta3N5 nanotubes. The electrodeposition time is varied and the optimized photoelectrode reaches a photocurrent density of 6.3 mA/cm2 at 1.23 V vs. SHE, ... -
The impact of the DNA glycosylase NEIL3 on neural coding of spatial learning and memory
(Doctoral theses at NTNU;2021:1, Doctoral thesis, 2021) -
Exploring the diagnostic potential of adding T2 dependence in diffusion-weighted MR imaging of the prostate
(Peer reviewed; Journal article, 2021)Background: Magnetic resonance imaging (MRI) is essential in the detection and staging of prostate cancer. However, improved tools to distinguish between low-risk and high-risk cancer are needed in order to select the ... -
Erythrocyte Transfusion and Long-Term Mortality in Open Heart Surgery in Adults
(Doctoral theses at NTNU;2021:196, Doctoral thesis, 2021)Background Approximately 3,000 cases of cardiac surgery with cardiopulmonary bypass are performed each year in Norway. Cardiac surgery is performed to treat various disease of the heart, which includes ischemic, valvular, ... -
A survey of anaesthesia practices at all hospitals performing caesarean sections in Sierra Leone
(Peer reviewed; Journal article, 2020)Background Providing safe anaesthesia is essential when performing caesarean sections, one of the most commonly performed types of surgery. Anaesthesia-related causes of maternal mortality are generally considered ... -
Early Gut Fungal and Bacterial Microbiota in Growth and Allergy-Related Diseases
(Doctoral theses at NTNU;2021:204, Doctoral thesis, 2021)TIDLEG SOPP- OG BAKTERIEMIKROBIOTA I VEKST OG ALLERGIRELATERTE SJUKDOMMAR BARNETARMFLORA I VEKST- OG ALLERGIUTVIKLING Det er ikkje tvil om at tarmflora er i vinden for tida. Endeleg har forskarar kunna djupdukke ned i ... -
Urinary and colorectal-anal distress in women - prevalence, risk factors and effect of pelvic floor muscle exercise in women with pelvic organ prolapse
(Doctoral theses at NTNU;2021:199, Doctoral thesis, 2021) -
Polycystic ovary syndrome and extremely preterm birth: A nationwide register-based study
(Peer reviewed; Journal article, 2021)Women with polycystic ovary syndrome (PCOS) have increased risk of pregnancy complications, including preterm birth before 37 weeks. However, if this increased risk also includes extremely preterm births (<28 weeks) is ...
RSS 2.0