• Mycoplasma genitalium Macrolide-resistance and treatment options 

  Gossé, Marianne (Doctoral theses at NTNU;2020:360, Doctoral thesis, 2020)

• Pain and Fatigue in Young Adults with Juvenile Idiopathic Arthritis – Based on A Nordic Prospective Longitudinal Study 

  Arnstad, Ellen Dalen (Doctoral theses at NTNU;2020:3019, Doctoral thesis, 2020)

• Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort. 

  Glerup, Mia; Stoustrup, Peter Bangsgaard; Matzen, Louise Hauge; Rypdal, Veronika Gjertsen; Nordal, Ellen Berit; Frid, Paula; Arnstad, Ellen Dalen; Rygg, Marite; Thorarensen, Olafur; Ekelund, Maria; Berntson, Lillemor; Fasth, Anders; Nilsson, H; Peltoniemi, Suvi; Aalto, Kristiina; Arte, Sirpa; Toftedal, Peter; Nielsen, Susan; Kreiborg, S.; Herlin, T; Pedersen, T. (Peer reviewed; Journal article, 2020)

  Objective. To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset. Methods. Drawn from ...

• Genetic interaction between the non‐homologous end joining factors during B and T lymphocyte development: in vivo mouse models 

  Castaneda Zegarra, Sergio Miguel; Fernandez Berrocal, Marion Silvana; Tkachev, Max; Yao, Rouan; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)

  Non-homologous end joining (NHEJ) is the main DNA repair mechanism for the repair of double-strand breaks (DSBs) throughout the course of the cell cycle. DSBs are generated in developing B and T lymphocytes during V(D)J ...

• The Role of IL-32 in Multiple Myeloma 

  Aass, Kristin Roseth (Doctoral theses at NTNU;2020:256, Doctoral thesis, 2020)

• Pelvic floor muscle contraction and anatomy in women with pelvic organ prolapse, incontinence and in pregnancy 

  Nyhus, Maria Øyasæter (Doctoral theses at NTNU;2020:261, Doctoral thesis, 2020)

• Towards understanding of gastric cancer based upon physiological role of gastrin and ECL cells 

  Waldum, Helge; Mjønes, Patricia (Peer reviewed; Journal article, 2020)

  The stomach is an ideal organ to study because the gastric juice kills most of the swallowed microbes and, thus, creates rather similar milieu among individuals. Combined with a rather easy access to gastric juice, gastric ...

• Early gut fungal and bacterial microbiota and childhood growth 

  Schei, Kasper; Simpson, Melanie Rae; Avershina, Ekaterina; Rudi, Knut; Øien, Torbjørn; Juliusson, Petur Benedikt; Underhill, David; Salamati, Saideh; Ødegård, Rønnaug (Peer reviewed; Journal article, 2020)

  Introduction: Childhood growth is a sensitive marker of health. Animal studies show increased height and weight velocity in the presence of fungal as well as antibiotic supplement in feed. Human studies on early gut ...

• Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee. 

  Giancane, Gabriella; Swart, Joost Frans; Castagnola, E; Groll, Andreas; Horneff, Gerd; Huppertz, Hans-Iko; Lovell, Daniel J.; Wolfs, T.; Herlin, T; Dolezalova, Pavla; Sanner, Helga; Susic, Gordana; Sztajnbok, Flavio; Maritsi, Despoina; Constantin, Tamás; Vargova, Veronika; Sawhney, Sujata; Rygg, Marite; Oliveira, Sheila K.; Cattalini, Marco; Bovis, Francesca; Bagnasco, Francesca; Pistorio, Angela; Martini, Alberto; Wulffraat, Nico; Ruperto, Nicolino (Peer reviewed; Journal article, 2020)

  Background: To derive a list of opportunistic infections (OI) through the analysis of the juvenile idiopathic arthritis (JIA) patients in the Pharmachild registry by an independent Safety Adjudication Committee (SAC). ...

• Pain sensitivity in young adults with juvenile idiopathic arthritis: a quantitative sensory testing study 

  Arnstad, Ellen Dalen; Iversen, Johanne Marie; Uglem, Martin; Glerup, Mia; Romundstad, Pål Richard; Sand, Trond; Rygg, Marite (Peer reviewed; Journal article, 2020)

  Background: To study for the first-time, pain perception, pain sensitivity, and self-reported pain in young adults with long disease duration of juvenile idiopathic arthritis (JIA) compared with controls. Methods: Children ...

• Construction and evaluation of the performance of genetic risk scores for ankylosing spondylitis, rheumatoid arthritis, and myocardial infarction in the Norwegian population-based Nord- Trøndelag Health Study (HUNT) 

  Rostami, Sina (Doctoral theses at NTNU;2020:176, Doctoral thesis, 2020)

• Dietary changes in early-stage breast cancer patients from pre-surgery and over the 12 months post-surgery 

  Brunvoll, Sonja Hjellegjerde; Thune, Inger; Bertheussen, Gro Falkener; Fjeldheim, Frøydis Nyborg; Flote, Vidar Gordon; Frydenberg, Hanne; Lundgren, Steinar; Skjerven, Helle; Lømo, Jon; Fagerland, Morten; McTiernan, Anne; Schlichting, Ellen; Hjartåker, Anette (Peer reviewed; Journal article, 2020)

  The time after a breast cancer diagnosis is a potential period for making positive dietary changes, but previous results are conflicting. The main aim of the present study was to study breast cancer patients’ dietary changes ...

• Oxytocin treatment in alcohol dependence A double-blind randomized controlled trial 

  Melby, Katrine (Doctoral theses at NTNU;2020:168, Doctoral thesis, 2020)

  Nesespray for alkoholavhengighet? Alkohol er det største rusproblemet i Norge og den nest viktigste risikofaktoren for tap av friske leveår i vår del av verden. Det er medisinske utfordringer knyttet til alkoholavhengighet, ...

• Developmental Course and Risk Factors of Physical Aggression in Late Adolescence 

  Henriksen, Marit; Skrove, Marit Synnøve; Hoftun, Gry Børmark; Sund, Erik; Lydersen, Stian; Tseng, Wan-Ling; Sukhodolsky, Denis G. (Peer reviewed; Journal article, 2020)

  This study examined risk factors of physical aggression during transition from early to late adolescence using a two-wave longitudinal study. Specifically, we examined if risk factors in early adolescence predict physically ...

• Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women 

  Steinthorsdottir, Valgerdur; McGinnis, Ralph; Williams, Nicholas O.; Stefánsdóttir, Lilja; Thorleifsson, Gudmar; Shooter, Scott; Fadista, João; Sigurdsson, Jon K.; Auro, Kirsi; Berezina, Galina; Borges, Maria-Carolina; Bumpstead, Suzannah; Bybjerg-Grauholm, Jonas; Colgiu, Irina; Dolby, Vivien A.; Dudbridge, Frank; Engel, Stephanie M.; Franklin, Christopher S.; Frigge, Michael L; Frisbaek, Yr; Geirsson, Reynir T.; Geller, Frank; Gretarsdottir, Solveig; Gudbjartsson, Daniel F.; Harmon, Quaker; Hougaard, David Michael; Hegay, Tatyana; Helgadottir, Anna; Hjartardóttir, Sigrún; Jääskeläinen, Tiina; Johannsdottir, Hrefna; Jonsdottir, Ingileif; Juliusdottir, Thorhildur; Kalsheker, Noor; Kasimov, Abdumadjit; Kemp, John P.; Kivinen, Katja; Klungsøyr, Kari; Lee, Wai K; Melbye, Mads; Miedzybrodska, Zosia; Moffett, Ashley; Najmutdinova, Dilbar; Nishanova, Firuza; Olafsdottir, Thorunn; Perola, Markus; Pipkin, Fiona Broughton; Poston, Lucilla; Prescott, Gordon; Saevarsdottir, Saedis; Salimbayeva, Damilya; Scaife, Paula Juliet; Skotte, Line; Staines-Urias, Eleonora; Stefansson, Olafur A.; Sørensen, Karina Meden; Thomsen, Liv Cecilie Vestrheim; Tragante, Vinicius; Trogstad, Lill; Simpson, Nigel A.B.; Aripova, Tamara; Casas, Juan P; Dominiczak, Anna F; Walker, James J.; Thorsteinsdottir, Unnur; Iversen, Ann-Charlotte; Feenstra, Bjarke; Lawlor, Deborah A.; Boyd, Heather Allison; Magnus, Per; Laivuori, Hannele; Zakhidova, Nodira; Syvatova, Gulnara; Stefansson, Kari; Morgan, Linda (Peer reviewed; Journal article, 2020)

  Preeclampsia is a serious complication of pregnancy, affecting both maternal and fetal health. In genome-wide association meta-analysis of European and Central Asian mothers, we identify sequence variants that associate ...

• Non-Homologous End Joining Factors XLF, PAXX and DNA-PKcs Maintain the Neural Stem and Progenitor Cell Population 

  Gago-Fuentes, Raquel; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)

  Non-homologous end-joining (NHEJ) is a major DNA repair pathway in mammalian cells that recognizes, processes and fixes DNA damage throughout the cell cycle and is specifically important for homeostasis of post-mitotic ...

• Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19 

  Jørgensen, Marthe Jøntvedt; Holter, Jan Cato; Christensen, Erik; Schjalm, Camilla; Tonby, Kristian; Pischke, Soeren; Jenum, Synne; Skeie, Linda Gail; Nur, Sarah; Lind, Andreas; Opsand, Hanne; Enersen, Tone Burvald; Grøndahl, Ragnhild; Hermann, Anne; Dudman, Susanne Gjeruldsen; Müller, Fredrik; Ueland, Thor; Mollnes, Tom Eirik; Aukrust, Pål; Heggelund, Lars; Holten, Aleksander Rygh; Dyrhol-Riise, Anne Ma (Peer reviewed; Journal article, 2020)

  In SARS-CoV-2 infection there is an urgent need to identify patients that will progress to severe COVID-19 and may benefit from targeted treatment. In this study we analyzed plasma cytokines in COVID-19 patients and ...

• HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data 

  Farooq, Amna; Grønmyr, Sindre; Omer, Ali Avan; Rognes, Torbjørn; Scheffler, Katja; Bjørås, Magnar; Wang, Junbai (Peer reviewed; Journal article, 2020)

  DNA methylation (5mC) and hydroxymethylation (5hmC) are chemical modifications of cytosine bases which play a crucial role in epigenetic gene regulation. However, cost, data complexity and unavailability of comprehensive ...

• Innate immune responses to human metapneumovirus - Exploring cellular models and molecular mechanisms of interferon regulation and action 

  Loevenich, Simon (Doctoral theses at NTNU;2020:101, Doctoral thesis, 2020)

  Luftveisinfeksjoner forårsaket av virus og bakterier er et betydelig folkehelseproblem. Særlig for barn, gamle mennesker og personer med lungesykdom eller svekket immunsystem kan disse infeksjonene være livstruende. For ...

• European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia 

  Hochhaus, Andreas; Baccarani, Michele; Silver, Richard T.; Schiffer, Charles A.; Apperley, Jane F.; Cervantes, Francisco; Clark, Richard E.; Cortes, Jorge Eduardo; Deininger, Michael Werner Nikolaus; Guilhot, François; Hjorth-Hansen, Henrik; Hughes, Timothy Peter; Janssen, Jeroen J.W.M.; Kantarjian, Hagop M.; Kim, Dong-Wook; Larson, Richard A.; Lipton, Jeffrey Howard; Mahon, François-Xavier; Mayer, Jiří; Nicolini, Franck Emmanuel; Niederwieser, Dietger Walter; Pane, Fabrizio; Radich, Jerald P.; Réa, Delphine; Richter, Johan; Rosti, Gianantonio; Rousselot, Philippe; Saglio, Giuseppe; Saußele, Susanne; Soverini, Simona; Steegmann, Juan Luis; Turkina, Anna; Zaritskey, Andrey Yu.; Hehlmann, Rüediger (Peer reviewed; Journal article, 2020)

  The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy. Another goal is achieving a stable deep ...

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