• Outcomes of obstructed abdominal wall hernia: results from the UK national small bowel obstruction audit 

  Bolkan, Håkon Angell; National Audit of Small Bowel, NASBO Collaborators (Peer reviewed; Journal article, 2020)

  Background Abdominal wall hernia is a common surgical condition. Patients may present in an emergency with bowel obstruction, incarceration or strangulation. Small bowel obstruction (SBO) is a serious surgical condition ...

• Active components of commonly prescribed medicines affect influenza a virus–host cell interaction: A pilot study 

  Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lysvand, Hilde; Oksenych, Valentyn; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2021)

  Background: Every year, millions of people are hospitalized and thousands die from influenza A virus (FLUAV) infection. Most cases of hospitalizations and death occur among the elderly. Many of these elderly patients are ...

• Validity of Estimated Cardiorespiratory Fitness in Patients With Primary Breast Cancer 

  Michalski, Meghan; Rowed, Kylie; Lavery, Jessica A; Moskowitz, Chaya S; Capaci, Catherine; Stene, Guro Birgitte; Edvardsen, Elisabeth; Eves, Neil D; Jones, Lee W.; Scott, Jessica M (Peer reviewed; Journal article, 2022)

  Background Estimated peak oxygen consumption (Vo2peak) is widely used in oncology; however, estimated Vo2peak equations were developed in noncancer settings. Objectives The aim of this study was to evaluate the ...

• Metabolic adaptation is associated with less weight and fat mass loss in response to low-energy diets 

  Martins, Catia; Røkenes, Jessica Ann; Gower, Barbara A.; Hunter, Gary R. (Peer reviewed; Journal article, 2021)

  Background: The practical relevance of metabolic adaptation remains a controversial issue. To the best of our knowledge, no study has properly evaluated the role of metabolic adaptation in modulating weight loss outcomes. ...

• Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys 

  Jager, Neeltina M.; Venema, Leonie H.; Arykbaeva, Asel S.; Meter-Arkema, Anita H.; Ottens, Petra J.; van Kooten, Cees; Mollnes, Tom Eirik; Alwayn, Ian P. J.; Leuvenink, Henri G. D.; Pischke, Soeren (Peer reviewed; Journal article, 2022)

  Background: The gap between demand and supply of kidneys for transplantation necessitates the use of kidneys from extended criteria donors. Transplantation of these donor kidneys is associated with inferior results, reflected ...

• Definitive radiotherapy for prostate cancer in Norway 2006-2015: Temporal trends, performance and survival 

  Fosså, Sophie Dorothea; Aas, Kirsti; Muller, Christoph Rainer; Jerm, Marianne Brenn; Tandstad, Torgrim; Lilleby, Wolfgang; Kvåle, Rune; Gulbrandsen, Johanne; Haug, Erik Skaaheim; Myklebust, Tor Åge (Peer reviewed; Journal article, 2020)

  Background: More studies are needed to document nation-wide use and effectiveness of curative definitive radiotherapy (Def-RT) in the treatment of prostate cancer (PCa). Patients and methods: For 38,960 men diagnosed with ...

• Trends in Prevalence and Severity of Pre/Perinatal Cerebral Palsy Among Children Born Preterm From 2004 to 2010: A SCPE Collaboration Study 

  Arnaud, Catherine; Ehlinger, Virginie; Delobel, Malika; Klapouszczak, Dana; Perra, Oliver; Hensey, Owen; Neubauer, David; Hollody, Katalin; Virella, Daniel; Rackauskaite, Gija; Greitane, Andra; Himmelmann, Kate; Ortibus, Elodie; Dakovic, Ivana; Andersen, Guro Lillemoen; Papavasiliou, Antigone; Sellier, Elodie; Platt, Mary Jane; Krageloh-Mann, Inge (Peer reviewed; Journal article, 2021)

  Aim: To report on prevalence of cerebral palsy (CP), severity rates, and types of brain lesions in children born preterm 2004 to 2010 by gestational age groups. Methods: Data from 12 population-based registries of the ...

• Peripheral blood cells inform on the presence of breast cancer: A population‐based case–control study 

  Dumeaux, Vanessa; Ursini‐Siegel, Josie; Flatberg, Arnar; Fjøsne, Hans Erikssønn; Frantzen, Jan Ole; Holmen, Marit Muri; Rodegerdts, Enno; Schlichting, Ellen; Lund, Eiliv (Journal article; Peer reviewed, 2015)

  Tumor–host interactions extend beyond the local microenvironment and cancer development largely depends on the ability of malignant cells to hijack and exploit the normal physiological processes of the host. Here, we ...

• Vinorelbine and gemcitabine vs vinorelbine and carboplatin as first-line treatment of advanced NSCLC. A phase III randomised controlled trial by the Norwegian Lung Cancer Study Group 

  Fløtten, Øystein; Grønberg, Bjørn Henning; Bremnes, Roy M.; Amundsen, Tore; Sundstrøm, Stein Harald; Rolke, Heidi; HORNSLIEN, KJERSTI; Wentzel-Larsen, Tore; Aasebø, Ulf; von Plessen, Christian (Journal article; Peer reviewed, 2012)

  Background: Platinum-based doublet chemotherapy is the standard first-line treatment for advanced non-small cell lung cancer (NSCLC), but earlier studies have suggested that non-platinum combinations are equally effective ...

• Transitioning patients with juvenile idiopathic arthritis to adult care: the Nordic experience 

  Mikola, Katriina; Rebane, Katariina; Arnstad, Ellen Dalen; Berntson, Lillemor; Fasth, Anders; Glerup, Mia; Herlin, Troels; Kautiainen, Hannu; Nielsen, Susan; Nordal, Ellen Berit; Peltoniemi, Suvi; Rygg, Marite; Rypdal, Veronika; Zak, Marek; Aalto, Kristiina (Peer reviewed; Journal article, 2022)

  Background With juvenile idiopathic arthritis (JIA), there are several protocols and practices used worldwide for the transition from paediatric to adult care. In this study, we examined the transferral rates and disease ...

• Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene 

  Emblem, Åse; Knutsen, Erik; Jørgensen, Tor Erik; Fure, Hilde; Johansen, Steinar Daae; Brekke, Ole Lars; Mollnes, Tom Eirik; Karlsen, Bård Ove (Peer reviewed; Journal article, 2022)

  Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood transcriptome undergoes programmed expression of coding and long ...

• Diagnostic stewardship aiming at expectorated or induced sputum promotes microbial diagnosis in community-acquired pneumonia 

  Waagsbø, Bjørn; Buset, Eva Margrethe; Longva, Jørn-Åge; Bjerke, Merete; Bakkene, Birgitte; Ertesvåg, Anne-Stine; Holmen, Hanne; Nikodojevic, Marko; Tran, To Thy; Christensen, Andreas; Nilsen, Einar; Damås, Jan Kristian; Heggelund, Lars (Peer reviewed; Journal article, 2022)

  Purpose Studies on aetiology of community-acquired pneumonia (CAP) vary in terms of microbial sampling methods, anatomical locations, and laboratory analyses, since no gold standard exists. In this large, multicentre, ...

• Photodynamic Effects with 5-Aminolevulinic Acid on Cytokines and Exosomes in Human Peripheral Blood Mononuclear Cells 

  Espeland, Kristian; Kleinauskas, Andrius; Juzenas, Petras; Brech, Andreas; Darvekar, Sagar; Vasovic, Vlada; Warloe, Trond; Christensen, Eidi; Jahnsen, Jørgen; Qian, Peng (Peer reviewed; Journal article, 2022)

  Photodynamic therapy (PDT) with 5-aminolevulinic acid (ALA), a precursor to the potent photosensitizer, protoporphyrin IX (PpIX), is an established modality for several malignant and premalignant diseases. This treatment ...

• MS-proteomics provides insight into the host responses towards alginate microspheres 

  Coron, Abba Elizabeth; Fonseca, Davi de Miranda; Sharma, Animesh; Slupphaug, Geir; Strand, Berit Løkensgard; Rokstad, Anne Mari A. (Journal article; Peer reviewed, 2022)

  Protein adsorption to biomaterial surfaces is considered a determining factor for the host response. Here we detail the protein adsorption profiles of alginate hydrogel microspheres relevant for cell therapy using mass ...

• A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders 

  Suarez, Anna; Lahti, Jari; Lahti-Pulkkinen, Marius; Girchenko, Polina; Czamara, Darina; Arloth, Janine; Malmberg, Anni LK.; Hämäläinen, Esa; Kajantie, Eero Olavi; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Provençal, Nadine; Binder, Elisabeth B.; Räikkönen, Katri (Peer reviewed; Journal article, 2020)

  Background Maternal depression and anxiety during pregnancy may enhance fetal exposure to glucocorticoids (GCs) and harm neurodevelopment. We tested whether a novel cross-tissue polyepigenetic biomarker indicative of in ...

• LncRNA MORT (ZNF667-AS1) in Cancer—Is There a Possible Role in Gynecological Malignancies? 

  Di Fiore, Riccardo; Suleiman, Sherif; Drago-Ferrante, Rosa; Félix, Ana; O’Toole, Sharon A.; O’Leary, John J.; Ward, Mark P.; Beirne, James; Yordanov, Angel; Vasileva-Slaveva, Mariela; Subbannayya, Yashwanth; Pentimalli, Francesca; Giordano, Antonio; Calleja-Agius, Jean (Peer reviewed; Journal article, 2021)

  Gynecological cancers (GCs) are currently among the major threats to female health. Moreover, there are different histologic subtypes of these cancers, which are defined as ‘rare’ due to an annual incidence of <6 per 100,000 ...

• Higher blood pressure in normal weight women with pcos compared to controls 

  Mellembakken, Jan Roar; Mahmoudan, azita; Mørkrid, Lars; Sundström-Poromaa, Inger; Morin-Papunen, Laure; Tapanainen, Juha S.; Piltonen, Terhi T.; Hirschberg, Angelica L.; Stener-Victorin, Elisabet; Vanky, Eszter; Ravn, Pernille; Jensen, Richard Christian; Andersen, Marianne; Glintborg, Dorte (Peer reviewed; Journal article, 2021)

  Objective Obesity is considered to be the strongest predictive factor for cardio-metabolic risk in women with polycystic ovary syndrome (PCOS). The aim of the study was to compare blood pressure (BP) in normal weight women ...

• The Burden of Human Coronavirus in Norwegian Children hospitalized with Respiratory Tract Infections 

  Heimdal, Inger (Doctoral theses at NTNU;2022:359, Doctoral thesis, 2022)

• Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond 

  Jarmund, Anders Hagen; Giskeødegård, Guro F.; Ryssdal, Mariell; Steinkjer, Bjørg; Stokkeland, Live Marie; Madssen, Torfinn Støve; Stafne, Signe Nilssen; Stridsklev, Solhild; Moholdt, Trine; Heimstad, Runa Kristine; Vanky, Eszter; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2021)

  Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ...

• Anxiety and depression symptoms, albuminuria and risk of acute myocardial infarction in the Norwegian HUNT cohort study 

  Gustad, Lise Tuset; Myklebust, Tor Åge; Bjerkeset, Ottar; Williams, Lana J; Laugsand, Lars Erik; Dalen, Håvard; Berk, Michael; Romundstad, Solfrid (Peer reviewed; Journal article, 2022)

  Background Studies suggest increased risk for an outcome in people with joint exposures that share common causal pathways. The objective of this study was to determine the risk of incident acute myocardial infarction ...

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