• External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis 

  Snell, Kym I.E.; Allotey, John; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; Von Dadelszen, Peter; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony; Arenas Ramírez, Javier; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, Ahmet A.; Seed, Paul T.; Prefumo, Federico; da Silva Costa, Fabricio; Groen, Henk; Audibert, Francois; Masse, Jacques; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, Chie; Rumbold, Alice R.; Heinonen, Seppo; Askie, Lisa; Smits, Luc; Vinter, Christina; Magnus, Per; Eero, Kajantie; Villa, Pia M.; Jenum, Anne Karen; Andersen, Louise B.; Norman, Jane E.; Ohkuchi, Akihide; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala; Galindo, Alberto; Herraiz, Ignacio; Carbillon, Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Browne, Joyce L.; Moons, Karel G.M.; Riley, Richard D.; Thangaratinam, Shakila (Peer reviewed; Journal article, 2020)

  Background Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk during pregnancy is required to plan management. Although there are many published ...

• Long-term work outcomes and the efficacy of multidisciplinary rehabilitation programs on labor force participation in cancer patients - a protocol for a longitudinal prospective cohort study 

  Engan, Harald; Oldervoll, Line Merethe; Bertheussen, GF; Gaarder, MH; Nielsen, Roy; Paraponaris, Alain; Stene, GB; Tandstad, Torgrim; Torp, Steffen (Journal article; Peer reviewed, 2020)

  Background. Many cancer survivors experience late effects of cancer treatment and therefore struggle to return to work. Norway provides rehabilitation programs to increase labor force participation for cancer survivors ...

• Genetic variants related to physical activity or sedentary behaviour: a systematic review 

  Aasdahl, Lene; Nilsen, Tom Ivar Lund; Meisingset, Ingebrigt; Nordstoga, Anne Lovise; Evensen, Kari Anne Indredavik; Paulsen, Julie; Mork, Paul Jarle; Skarpsno, Eivind S. (Peer reviewed; Journal article, 2021)

  Background Research shows that part of the variation in physical activity and sedentary behaviour may be explained by genetic factors. Identifying genetic variants associated with physical activity and sedentary behaviour ...

• Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

  Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Journal article; Peer reviewed, 2020)

  Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...

• Interaction between Fibroblasts and Immune Cells Following DNA Damage Induced by Ionizing Radiation 

  Ragunathan, Kalaiyarasi; Esnardo Upfold, Nikki Lyn; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)

  Cancer-associated fibroblasts (CAF) form the basis of tumor microenvironment and possess immunomodulatory functions by interacting with other cells surrounding tumor, including T lymphocytes, macrophages, dendritic cells ...

• HIV strategimøte : forelesningmanuskripter og sammendrag med anbefalinger 

  Åsjø, Birgitta; Samdal, Helvi Holm; Skar, Anne Grete; Haukenes, Gunnar; Nordbø, Svein Arne; Tveten, Yngvar; Jenum, Pål; Hoddevik, Gunnar Martin (Research report, 1997)

• Cholesterol crystals and NLRP3 mediated inflammation in the uterine wall decidua in normal and preeclamptic pregnancies 

  Silva, Gabriela; Gierman, Lobke; Rakner, Johanne Johnsen; Stødle, Guro; Mundal, Siv Boon; Thaning, Astrid Josefin; Sporsheim, Bjørnar; Elschot, Mattijs; Collett, Karin; Bjørge, Line; Aune, Marie Hjelmseth; Thomsen, Liv Cecilie Vestrheim; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2020)

  Preeclampsia is a hypertensive and inflammatory pregnancy disorder associated with cholesterol accumulation and inflammation at the maternal-fetal interface. Preeclampsia can be complicated with fetal growth restriction ...

• Stable incidence but regional differences in retinopathy of prematurity in Norway from 2009 to 2017 

  Grottenberg, Beanca Sofie Gjølberg; Korseth, Katinka Madtzog; Follestad, Turid; Stensvold, Hans Jørgen; Støen, Ragnhild; Austeng, Dordi (Peer reviewed; Journal article, 2020)

  Purpose To explore the changes over time and regional differences in the incidence of retinopathy of prematurity (ROP) in a national cohort of infants born <28 weeks' gestational age (GA). Methods A population‐based ...

• Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep 

  Bojarskaite, Laura; Bjørnstad, Daniel Marelius; Pettersen, Klas; Cunen, Celine; Hermansen, Gudmund Horn; Åbjørsbråten, Knut Sindre; Chambers, Anna; Sprengel, Rolf; Vervaeke, Koen Gerard Alois; Tang, Wannan; Enger, Rune; Nagelhus, Erlend Arnulf (Peer reviewed; Journal article, 2020)

  Astrocytic Ca2+ signaling has been intensively studied in health and disease but has not been quantified during natural sleep. Here, we employ an activity-based algorithm to assess astrocytic Ca2+ signals in the neocortex ...

• Targeting OGG1 arrests cancer cell proliferation by inducing replication stress 

  Visnes, Torkild; Benitez-Buelga, Carlos; Cázares-Körner, Armando; Sanjiv, Kumar; Hanna, Bishoy M F; Mortusewicz, Oliver; Rajagopal, Varshni; Albers, Julian J.; Hagey, Daniel W.; Bekkhus, Tove; Eshtad, Saeed; Baquero, Juan Miguel; Masuyer, Geoffrey; Wallner, Olov; Müller, Sarah; Pham, Therese; Gokturk, Camilla; Rasti, Azita; Suman, Sharda; Torres-Ruiz, Raúl; Sarno, Antonio; Wiita, Elisée; Homan, Evert; Karsten, Stella; Marimuthu, Karthick; Michel, M; Koolmeister, Tobias; Scobie, Martin; Loseva, Olga; Almlöf, Ingrid; Unterlass, Judith Edda; Pettke, Aleksandra; Boström, Johan; Pandey, Monica; Gad, Helge; Herr, Patrick; Jemth, Ann-Sofie; El Andaloussi, Samir; Kalderén, Christina; Rodriguez-Perales, Sandra; Benítez, Javier; Krokan, Hans Einar; Altun, Mikael; Stenmark, Pål; Berglund, Ulrika Warpman; Helleday, Thomas (Peer reviewed; Journal article, 2020)

  Abstract Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g. 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies ...

• Immunoregulatory roles of chemokines and epithelium in inflammatory bowel disease - CCL20 in mucosa, human colonoids and peripheral blood mononuclear cells 

  Skovdahl, Helene Kolstad (Doctoral theses at NTNU;2020:382, Doctoral thesis, 2020)

  Inflammatory bowel diseases (IBD) are characterized by chronic inflammation in the intestinal tract, which leads to substantial cost for the individual and for society. The pathogenesis is described as an inflammation ...

• Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation 

  Storm, Benjamin; Christiansen, Dorte; Mollnes, Tom Eirik; Nielsen, Erik Waage (Peer reviewed; Journal article, 2020)

  Background In vitro, the complement system can be studied in test tubes incubated with anticoagulated human whole-blood. Background activation of complement may mask inflammatory signals. Air bubbles are known to activate ...

• Incidence of invasive Group B Streptococcal infection and the risk of infant death and cerebral palsy: a Norwegian Cohort Study 

  Mynarek, Maren; Bjellmo, Solveig; Lydersen, Stian; Afset, Jan Egil; Andersen, Guro Lillemoen; Vik, Torstein (Peer reviewed; Journal article, 2020)

  Background Group B Streptococcus (GBS) is the leading cause of invasive neonatal infection worldwide. In high-income countries mortality rates are 4–10%, and among survivors of GBS meningitis 30–50% have neurodevelopmental ...

• Hypergastrinemia is associated with an increased risk of gastric adenocarcinoma with proximal location: A prospective population-based nested case-control study 

  Ness-Jensen, Eivind; Bringeland, Erling Audun; Mattsson, Fredrik; Mjønes, Patricia; Lagergren, Jesper; Grønbech, Jon Erik; Waldum, Helge; Fossmark, Reidar (Peer reviewed; Journal article, 2020)

  The incidence of proximal gastric adenocarcinoma is increasing among younger adults. Rodent models have shown that hypergastrinemia causes carcinogenesis in the proximal stomach. The aim of our study was therefore to assess ...

• Potential harms and benefits of planned cesarean delivery of fetuses in breech presentation at term. An observational study from Norway 

  Bjellmo, Solveig (Doctoral theses at NTNU;2020:334, Doctoral thesis, 2020)

  The optimal mode of delivery of a fetus in breech presentation has been debated for more than half a century and remains a controversial topic in modern obstetrics. Already in the 1950s, observational studies showed increased ...

• Quality of life in patients with advanced non-small-cell lung cancer 

  Kristensen, Are Korsnes (Doctoral theses at NTNU;2020:410, Doctoral thesis, 2020)

  Livskvalitet hos pasienter med lungekreft Lungekreft er den kreftformen som tar flest liv. Pasienter med lungekreft har ofte symptomer fra sykdommen, samtidig som de kan oppleve plagsomme bivirkninger fra behandling. ...

• Investigating the Role of PRL-3 and Targeting PHGDH in Multiple Myeloma 

  Elsaadi, Samah (Doctoral theses at NTNU;2020:378, Doctoral thesis, 2020)

  Myelomatose er en hematologisk kreftsykdom som skyldes klonal ekspansjon av plasmaceller som infiltrerer beinmargen. Til tross for fremskritt innen behandlingen av myelomatose, er sykdommen fortsatt uhelbredelig. Artiklene ...

• Elevated plasma sTIM-3 levels in patients with severe COVID-19 

  Ueland, Thor; Heggelund, Lars; Lind, Andreas; Holten, Aleksander Rygh; Tonby, Kristian; Michelsen, Annika; Jenum, Synne; Jørgensen, Marthe Jøntvedt; Barratt-Due, Andreas; Skeie, Linda Gail; Nordøy, Ingvild; Aanensen Fraz, Mai Sasaki; Paulsen, Else Quist; Pischke, Soeren; Johal, Simreen Kaur; Hesstvedt, Liv; Bogen, Mette; Fevang, Børre; Halvorsen, Bente; Müller, Fredrik; Bekken, Gry Kloumann; Mollnes, Tom Eirik; Dudman, Susanne Gjeruldsen; Aukrust, Pål; Dyrhol-Riise, Anne Ma; Holter, Jan Cato (Peer reviewed; Journal article, 2020)

  Background The pathogenesis of coronavirus disease 2019 (COVID-19) is still incompletely understood, but it seems to involve immune activation and immune dysregulation. Objective We examined the parameters of activation ...

• Mycoplasma genitalium Macrolide-resistance and treatment options 

  Gossé, Marianne (Doctoral theses at NTNU;2020:360, Doctoral thesis, 2020)

• Pain and Fatigue in Young Adults with Juvenile Idiopathic Arthritis – Based on A Nordic Prospective Longitudinal Study 

  Arnstad, Ellen Dalen (Doctoral theses at NTNU;2020:3019, Doctoral thesis, 2020)

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