• RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis 

  Zelic, Matija; Pontarelli, Fabrizio; Woodworth, Lisa; Zhu, Cheng; Mahan, Amy; Ren, Yi; LaMorte, Michael; Gruber, Ross; Keane, Aislinn; Loring, Pequita; Guo, Lilu; Xia, Tai-he; Zhang, Boyao; Ørning, Mathias Pontus; Lien, Egil; Degterev, Alexei; Hammond, Timothy; Ofengeim, Dimitry (Peer reviewed; Journal article, 2021)

• Syntese av fenylpropanoider ved bruk av trekomponentsyntese med Bestmann-ylid 

  Ryjoan Karwan Ahmed Ahmed (Master thesis, 2022)

  Fenylpropanoider er plante sekundærmetabolitter og har i de siste årene fått oppmerksomhet da de har vist forskjellige biologiske effekter. Målet for dette master prosjektet var å danne et kjemisk bibliotek av fenylpropanoid ...

• Et apatisk barn med hallusinasjoner 

  Teigen, Ingrid Anna; Berg, Jon Andsnes; Brodwall, Kristoffer (Peer reviewed; Journal article, 2021)

• SARS-CoV-2 antibody persistence after five and twelve months: A cohort study from South-Eastern Norway 

  Sarjomaa, Marjut Anneli; Diep, Lien My; Zhang, Chi; Tveten, Yngvar; Reiso, Harald; Thilesen, Carina; Nordbø, Svein Arne; Berg, Kristine Karlsrud; Aaberge, Ingeborg Aase S.; Pearce, Neil; Kersten, Hege; Vandenbroucke, Jan Paul; Eikeland, Randi; Fell, Anne Kristin M. (Peer reviewed; Journal article, 2022)

  Objectives: To assess total antibody levels against Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2) spike protein up to 12 months after Coronavirus Disease (COVID-19) infection in non-vaccinated individuals ...

• Longitudinal minimal residual disease assessment in multiple myeloma patients in complete remission - results from the NMSG flow-MRD substudy within the EMN02/HO95 MM trial 

  Schmitz, Alexander; Brøndum, Rasmus Froberg; Johnsen, Hans Erik; Mellqvist, Ulf-Henrik; Waage, Anders; Gimsing, Peter; Op Bruinink, Davine Hofste; van der Velden, Vincent; van der Holt, Bronno; Hansson, Markus; Andersen, Niels Frost; Frølund, Ulf Christian; Helleberg, Carsten; Schjesvold, Fredrik Hellem; Ahlberg, Lucia; Gulbrandsen, Nina; Andreasson, Bjorn; Lauri, Birgitta; Haukås, Einar; Bødker, Julie Støve; Roug, Anne Stidsholt; Bøgsted, Martin; Severinsen, Marianne T.; Gregersen, Henrik; Abildgaard, Niels; Sonneveld, Pieter; Dybkær, Karen (Peer reviewed; Journal article, 2022)

  Background Multiple myeloma remains an incurable disease with multiple relapses due to residual myeloma cells in the bone marrow of patients after therapy. Presence of small number of cancer cells in the body after cancer ...

• Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway 

  Helland, Åslaug; Russnes, Hege Elisabeth Giercksky; Fagereng, Gro Live; Al-Shibli, Khalid Ibrahim; Andersson, Yvonne; Berg, Thomas; Bjørge, Line; Blix, Egil Støre; Bjerkehagen, Bodil; Brabrand, Sigmund; CAMERON, MARTE; Dalhaug, Astrid; Dietzel, Dalia; Dønnem, Tom; Enerly, Espen; Flobak, Åsmund; Fluge, Sverre; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Grønberg, Bjørn Henning; Grønås, Kari; Guren, Tormod Kyrre; Hamre, Hanne Mari; Haug, Åse; Heinrich, Daniel; Hjortland, Geir Olav; Hovig, Eivind; Hovland, Randi; Iversen, Ann-Charlotte; Janssen, Emiel; Kyte, Jon A; Gythfeldt, Hedda; Lothe, Ragnhild Adelheid; Lund, Jo-Åsmund; Meza, Leonardo Zepeda; Munthe-Kaas, Monica Cheng; Nguyen, Olav Toai Duc; Niehusmann, Pitt; Nilsen, Hilde; Puco, Katarina; Ree, Anne Hansen; Riste, Tonje Bøyum; Semb, Karin; Steinskog, Eli Sihn Samdal; Stensvold, Andreas; Suhrke, Pål; Tennøe, Øyvind Krohn; Tjønnfjord, Geir Erland; Vassbotn, Liv Jorunn; Aas, Eline; Aasebø, Kristine Øverås; Tasken, Kjetil; Smeland, Sigbjørn (Peer reviewed; Journal article, 2022)

  Background Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed ...

• The development and validation of a high-capacity serological assay for celiac disease 

  Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg; Mjønes, Patricia; Rønne, Elin; Lundin, Knut; Sollid, Ludvig Magne; Ness-Jensen, Eivind (Peer reviewed; Journal article, 2022)

  Background The aim of the present study was to develop and clinically validate a high-throughput assay for serum IgA and IgG antibodies against transglutaminase-2 (TG2) and to determine appropriate assay cut-offs for ...

• Establishing Methodology and Best Practices for Metagenomic and Metatranscriptomic Study of the Human Gut Microbiome 

  Desiati, Indri (Master thesis, 2022)

  Due to its fundamental impact on overall health, the gut microbiome has emerged as one of the most popular research subjects over the last decade. It is believed that there are associations between gut microbial perturbation ...

• Increased incidence of inflammatory bowel disease on etanercept in juvenile idiopathic arthritis regardless of concomitant methotrexate use 

  van Straalen, Joeri W.; Krol, Roline; Giancane, Gabriella; Panaviene, Violeta; Ailioaie, Laura Marinela; Dolezalova, Pavla; Cattalini, Marco; Susic, Gordana; Sztajnbok, Flavio; Maritsi, Despoina; Constantin, Tamas; Sawhney, Sujata; Rygg, Marite; Oliveira, Sheila K.; Nordal, Ellen Berit; Saad-Magalhaes, C; Rubio-Perez, Nadina; Jelusic, Marija; de Roock, Sytze; Wulffraat, Nico; Ruperto, Nicolino; Swart, Joost Frans; International Trials Org, Paediatric Rheumatology (Peer reviewed; Journal article, 2021)

  Objectives: To describe risk factors for inflammatory bowel disease (IBD) development in a cohort of children with juvenile idiopathic arthritis (JIA). Methods: JIA patients who developed IBD were identified from the ...

• Electron Beam Sterilization of Poly(Methyl Methacrylate)—Physicochemical and Biological Aspects 

  Sharifi, Sina; Islam, Mohammad Mirazul; Sharifi, Hannah; Islam, Rakibul; Huq, Tahmida N.; Nilsson, Per; Mollnes, Tom Eirik; Tran, Khoa D.; Patzer, Corrina; Dohlman, Claes H.; Patra, Hirak K.; Paschalis, Eleftherios I.; Gonzalez-Andrades, Miguel; Chodosh, James (Peer reviewed; Journal article, 2021)

  Electron beam (E-beam) irradiation is an attractive and efficient method for sterilizing clinically implantable medical devices made of natural and/or synthetic materials such as poly(methyl methacrylate) (PMMA). As ionizing ...

• Genotyping of human adenovirus C by tiled amplicon sequencing 

  Toftemo, Anna Matilde (Master thesis, 2022)

  adenovirus (HAdV) er et vanlig humanpatogent virus som vanligvis forårsaker milde og selvbegrensende sykdommer i øvre luftveier eller i gastrointestinaltraktus. Alvorlige og livstruende infeksjoner kan imidlertid oppstå, ...

• Genetic Rescue of the Highly Inbred Norwegian Lundehund 

  Melis, Claudia; Pertoldi, Cino; Ludington, William Basil; Beuchat, Carol; Qvigstad, Gunnar; Stronen, Astrid Vik (Journal article; Peer reviewed, 2022)

  Augmenting the genetic diversity of small, inbred populations by the introduction of new individuals is often termed “genetic rescue“. An example is the Norwegian Lundehund, a small spitz dog with inbreeding-related health ...

• Parenteral Nutrition in Advanced Cancer: The Healthcare Providers’ Perspective 

  Balstad, Trude Rakel; Løhre, Erik T; Thoresen, Lene; Thronæs, Morten; Skjelvan, Laila Strand; Helgås, Ragnhild Green; Solheim, Tora S; Sand, Kari (Peer reviewed; Journal article, 2022)

  Introduction The evidence base for parenteral nutrition (PN) in advanced cancer patients is limited. We studied healthcare providers’ (HCPs’) experiences with PN in cancer patients, focusing on perceived treatment benefits ...

• Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study 

  Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)

  About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ...

• Impact of DNA double-strand break response factors on B and T lymphocyte development 

  Castañeda-Zegarra, Sergio Miguel (Doctoral theses at NTNU;2022:224, Doctoral thesis, 2022)

  Sammendrag på norsk Virkningen av DNA-dobbeltrådbrudd responsfaktorer på B- og T-lymfocytt utvikling De mest cytotoksiske DNA-skadene i en celle er forårsaket av brudd på dobbelttrådet DNA (DSB). NHEJ er en essensiell ...

• Kan fysioterapeuters praksis dokumenteres? Erfaringer og utfordringer fra FYSIOPRIM 

  Bones, Anita Formo; Evensen, Kari Anne Indredavik; Meisingset, Ingebrigt; Granviken, Fredrik; Vasseljen, Ottar; Woodhouse, Astrid (Peer reviewed; Journal article, 2020)

  Bakgrunn: Det er mangelfull informasjon om fysioterapi i primærhelsetjenesten når det gjelder hvilke pasienter som oppsøker fysioterapeut, hva slags behandling de får og hvordan det går med dem over tid. Hensikt: Hensikten ...

• Pregnancy outcomes according to the definition of gestational diabetes 

  Koivunen, Sanna; Viljakainen, Matti; Männistö, Tuija; Gissler, Mika; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2020)

  Objective To assess the frequency and perinatal outcomes of gestational diabetes mellitus (GDM) defined by the criteria according to the International Association of Diabetes in Pregnancy Study Group (IADPSG) and the ...

• Mre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication 

  Boeckemeier, L; Kraehenbuehl, R; Keszthelyi, A; Gasasira, MU; Vernon, EG; Beardmore, R; Vågbø, Cathrine Broberg; Chaplin, D; Gollins, S; Krokan, Hans Einar; Lambert, SAE; Paizs, B; Hartsuiker, Edgar (Peer reviewed; Journal article, 2020)

  The Mre11 nuclease is involved in early responses to DNA damage, often mediated by its role in DNA end processing. MRE11 mutations and aberrant expression are associated with carcinogenesis and cancer treatment outcomes. ...

• Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations 

  Flatby, Helene Marie; Rasheed, Humaira; Ravi, Anuradha; Thomas, Laurent; Liyanarachi, Kristin Vardheim; Afset, Jan Egil; DeWan, Andrew; Brumpton, Ben Michael; Hveem, Kristian; Åsvold, Bjørn Olav; Simonsen, Gunnar Skov; Furberg, Anne-Sofie; Damås, Jan Kristian; Solligård, Erik; Rogne, Tormod (Journal article; Peer reviewed, 2021)

  Objective: Lower respiratory tract infections (LRTIs) are a leading cause of morbidity and mortality worldwide. Few studies have previously investigated the genetic susceptibility and potential risk factors for LRTI. ...

• Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia 

  Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M.; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero Olavi; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel; Kere, Juha (Peer reviewed; Journal article, 2020)

  Background Fetal immune tolerance is crucial for pregnancy success. We studied the link between preeclampsia, a severe pregnancy disorder with uncertain pathogenesis, and fetal human leukocyte antigen G (HLA-G) and other ...

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