• Impact of thyrotropin receptor antibody levels on fetal development in two successive pregnancies in a woman with Graves' Disease 

  Bjørgaas, Marit Ragnhild Rokne; Farstad, Hanne; Christiansen, Sverre Christian; Blaas, Harm-Gerd Karl (Peer reviewed; Journal article, 2013)

  Background: Treatment with radioiodine for Graves’ disease regularly increases the level of antithyroid antibodies, and transplacental passage of stimulating thyrotropin receptor antibodies (TRAb) may cause fetal ...

• Sustained Maternal Hyperandrogenism During PCOS Pregnancy Reduced by Metformin in Non-obese Women Carrying a Male Fetus 

  Andræ, Frida; Abbott, David H.; Stridsklev, Solhild; Schmedes, Anne Vibeke; Odsæter, Ingrid Hov; Vanky, Eszter; Salvesen, Øyvind (Peer reviewed; Journal article, 2020)

  Context Large, longitudinal studies on androgen levels in pregnant women with polycystic ovary syndrome (PCOS) are lacking. While metformin has a mild androgen-lowering effect in non-pregnant women with PCOS, its effects ...

• Post mortem tissue distribution of quetiapine in forensic autopsies 

  Breivik, Håvard; Frost, Joachim; Løkken, Trine Nordgård; Slørdal, Lars (Peer reviewed; Journal article, 2020)

  The antipsychotic drug quetiapine is widely used, and increasingly prescribed off-label. Furthermore, quetiapine use has been linked to increased mortality rates, most likely due to a range of cardiovascular and metabolic ...

• Nephronectin as a matrix effector in cancer 

  Norvoll Magnussen, Synnøve; Toraskar, Jimita Prashant; Hadler-Olsen, Elin Synnøve; Steigedal, Tonje S.; Svineng, Gunbjørg (Peer reviewed; Journal article, 2021)

  The extracellular matrix protein nephronectin plays an important regulatory role during embryonic development, controlling renal organogenesis through integrin α8β1 association. Nephronectin has three main domains: five ...

• Computational Drug Repositioning and Experimental Validation of Ivermectin in Treatment of Gastric Cancer 

  Rabben, Hanne-Line; Andersen, Gøran Troseth; Ianevski, Aleksandr; Olsen, Magnus Kringstad; Kainov, Denis; Grønbech, Jon Erik; Wang, Timothy Cragin; Chen, Duan; Zhao, Chun-Mei (Peer reviewed; Journal article, 2021)

  Objective: The aim of the present study was repositioning of ivermectin in treatment of gastric cancer (GC) by computational prediction based on gene expression profiles of human and mouse model of GC and validations with ...

• The pen, the receiver and the pump: Exploring young children's experiences of having a parent with type 1 diabetes 

  Hansen, Julie; Ersfjord, Ellen Margrete Iveland (Peer reviewed; Journal article, 2021)

  In this article, we explore young children's experiences of having a parent with type 1 diabetes (T1D). In our research we found that the children's knowledge about T1D was not age related, and that some had more in‐depth ...

• Initial experience with positron emission tomography/computed tomography in addition to computed tomography and magnetic resonance imaging in preoperative risk assessment of endometrial cancer patients 

  Nordskar, Nina Jebens; Hagen, Bjørn; Ogarkov, Aleksei; Vesterfjell, Ellen Veronika; Salvesen, Øyvind; Aune, Guro (Peer reviewed; Journal article, 2021)

  Objective: Improved preoperative evaluation of lymph node status could potentially replace lymphadenectomy in women with endometrial cancer. PET/CT was routinely implemented in the preoperative workup of endometrial cancer ...

• Decidual and placental NOD1 is associated with inflammation in normal and preeclamptic pregnancies 

  Rakner, Johanne Johnsen; Silva, Gabriela; Mundal, Siv Boon; Thaning, Astrid Josefin; Elschot, Mattijs; Ostrop, Jenny; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Gierman, Lobke; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2021)

  Introduction: Inflammation is a normal physiological process that increases to harmful levels in preeclampsia. It affects the interaction between maternal immune cells and fetal trophoblasts at both sites of the maternal-fetal ...

• Assessing the role of genome-wide DNA methylation between smoking and risk of lung cancer using repeated measurements: the HUNT Study 

  Sun, Yi-Qian; Richmond, Rebecca C.; Suderman, Matthew; Min, Josine L; Battram, Thomas; Flatberg, Arnar; Beisvag, Vidar; Nøst, Therese Haugdahl; Guida, Florence; Jiang, Lin; Wahl, Sissel Gyrid Freim; Langhammer, Arnulf; Skorpen, Frank; Walker, Rosie M; Bretherick, Andrew D; Zeng, Yanni; Chen, Yue; Johansson, Mattias; Sandanger, Torkjel M; Relton, Caroline L; Mai, Xiao-Mei (Peer reviewed; Journal article, 2021)

  Background: It is unclear if smoking-related DNA methylation represents a causal pathway between smoking and risk of lung cancer. We sought to identify novel smoking-related DNA methylation sites in blood, with repeated ...

• Intraperitoneal insulin administration in pigs: Effect on circulating insulin and glucose levels 

  Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)

  Introduction The effect of intraperitoneal insulin infusion has limited evidence in the literature. Therefore, the aim of the study was to investigate the pharmacokinetics and pharmacodynamics of different intraperitoneal ...

• Claims for compensation from women with cervical cancer in Norway-A retrospective, descriptive study of a 12-year period 

  Ravlo, Merethe; Lieng, Marit; Bukholm, Ida Rashida Khan; Moen, Mette Haase; Vanky, Eszter (Peer reviewed; Journal article, 2020)

  Introduction: In Norway, all patient-reported claims for compensation are evaluated by The Norwegian System of Patient Injury Compensation (NPE). The number of claims from women with cervical cancer is rising, and the ...

• T.M. Gundem og medarbeidere svarer 

  Gundem, Trine; Olasveengen, Theresa M.; Schøndorf, Christina; Hovda, Knut Erik; Rostrup, Morten; Frøyshov, Sten; Undseth, Øystein; Tonby, Kristian; Holten, Aleksander Rygh; Sunde, Kjetil; Gaustad, Knut (Journal article; Peer reviewed, 2020)

• Asthma and asthma symptom control in relation to incidence of lung cancer in the HUNT study 

  Jiang, Lin; Sun, Yi-Qian; Langhammer, Arnulf; Brumpton, Ben Michael; Chen, Yu; Nilsen, Tom Ivar Lund; Leivseth, Linda; Wahl, Sissel Gyrid Freim; Mai, Xiao-Mei (Peer reviewed; Journal article, 2021)

  Large prospective studies on asthma, especially asthma symptom control, as a potential risk factor for lung cancer are limited. We followed up 62,791 cancer-free Norwegian adults from 1995–1997 to 2017. Self-reported ...

• Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and females 

  Helgadottir, Holmfridur; Lund, Sigrun H; Gizurason, Sveinbjørn; Waldum, Helge; Björnsson, Einar B (Peer reviewed; Journal article, 2020)

  Objective Gastrin elevation secondary to proton pump inhibitor (PPI) therapy is well documented. Recent studies have demonstrated a sex-related difference where females on PPIs have significantly higher baseline gastrin ...

• A survey of anaesthesia practices at all hospitals performing caesarean sections in Sierra Leone 

  Lonnee, Herman; Taule, Katinka; Sandvand, Johanne Knoph; Koroma, Michael M.; Dumbuya, Abubakar; Jusu, Kakpama S.K.; Shour, Mohamed A.; van Duinen, Aalke Johan (Peer reviewed; Journal article, 2020)

  Background Providing safe anaesthesia is essential when performing caesarean sections, one of the most commonly performed types of surgery. Anaesthesia‐related causes of maternal mortality are generally considered ...

• Phosphatase of Regenerating Liver-3 Regulates Cancer Cell Metabolism in Multiple Myeloma 

  Abdollahi, Pegah; Vandsemb, Esten; Elsaadi, Samah; Røst, Lisa Marie; Yang, Rui; Hjort, Magnus Aassved; Andreassen, Trygve; Misund, Kristine; Slørdahl, Tobias Schmidt; Rø, Torstein Baade; Sponaas, Anne-Marit; Moestue, Siver Andreas; Bruheim, Per; Børset, Magne (Peer reviewed; Journal article, 2021)

  Cancer cells often depend on microenvironment signals from molecules such as cytokines for proliferation and metabolic adaptations. PRL‐3, a cytokine‐induced oncogenic phosphatase, is highly expressed in multiple myeloma ...

• The prognostic value of methylation signatures and NF2 mutations in atypical meningiomas 

  Meta, Rahmina; Boldt, Henning B.; Kristensen, Bjarne W.; Sahm, Felix; Sjursen, Wenche; Torp, Sverre Helge (Peer reviewed; Journal article, 2021)

  Background: Due to the solely subjective histopathological assessment, the WHO 2016 classification of human meningiomas is subject to interobserver variation. Consequently, the need for more reliable and objective markers ...

• Neural signaling modulates metabolism of gastric cancer 

  Rabben, Hanne-Line; Andersen, Gøran Troseth; Olsen, Magnus Kringstad; Øverby, Anders; Ianevski, Aleksandr; Kainov, Denis; Wang, Timothy Cragin; Lundgren, Steinar; Grønbech, Jon Erik; Chen, Duan; Zhao, Chun-Mei (Peer reviewed; Journal article, 2021)

  Tumors comprise cancer cells and the associated stromal and immune/inflammatory cells, i.e., tumor microenvironment (TME). Here, we identify a metabolic signature of human and mouse model of gastric cancer and show that ...

• Evolution and risk factors of anal incontinence during the first 6 years after first delivery: a prospective cohort study 

  Johannessen, Hege Hølmo; Mørkved, Siv; Stordahl, Arvid; Wibe, Arne; Falk, Ragnhild Sørum (Journal article; Peer reviewed, 2020)

• Bladder cancer from bench to bedside: Sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. 

  Blindheim, Augun Jodis (Doctoral theses at NTNU;2021:72, Doctoral thesis, 2021)

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