Browsing Institutt for klinisk og molekylær medisin by Title

Now showing items 2030-2049 of 2077

    • Vagotomy and Gastric Tumorigenesis 

      Rabben, Hanne-Line; Zhao, Chun-Mei; Hayakawa, Yoku; Wang, Timothy C.; Chen, Duan (Journal article, 2016)
      Vagotomy reduces gastric acid secretion and was therefore introduced as a surgical treatment for peptic ulcers in the 1970s. Later, it was replaced by acid reducing medication, such as histamine type 2 (H2) receptor ...

    • Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis 

      Allotey, John; Snell, Kym I.E.; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; von Dadelszen, Peter; Dodds, Julie; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid S.; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony O.; Ramírez, Javier A.; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, AA; Seed, PT; Prefumo, F; da Silva Costa, F; Groen, H; Audibert, F; Masse, J; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, C; Rumbold, Alice R.; Heinonen, Seppo; Askie, LM; Smits, LJ; Vinter, CA; Magnus, Per; Kajantie, Eero Olavi; Villa, PM; Jenum, Anne Karen; Andersen, LB; Norman, JE; Ohkuchi, A; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala M.; Galindo, Alberto; Herraiz, Ignacio; Carbillon, , Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Teede, Helena J.; Browne, Joyce L; Moons, Karel G.M.; Riley, Richard D; Thangaratinam, Shakila (Peer reviewed; Journal article, 2020)
      Background: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. Objectives: To assess the performance of existing pre-eclampsia ...

    • Validation of FRAX and the impact of self-reported falls among elderly in a general population: the HUNT study, Norway 

      Hoff, Mari; Meyer, Haakon E; Skurtveit, Svetlana; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Dhainaut, Alvilde; Skovlund, Eva; Abrahamsen, B; Schei, Berit (Journal article; Peer reviewed, 2017)
      Summary Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD) for hip fracture prediction was validated in a Norwegian population 50–90 years. Fracture risk increased with higher FRAX score, and the ...

    • Validation of Housekeeping Genes for the Use as Endogenous Controls in Real-Time PCR in Multiple Myeloma 

      Hossain, Md. Sabbir (Master thesis, 2012)
      Multiple myeloma (MM) is a cancer of malignant plasma cells in the bone marrow, and leads to the development of one or more clinical manifestations such as bone destruction, anaemia, and renal insufficiency. The analysis ...

    • Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1-results of the Canadian model in the Nordic cohort. 

      Rypdal, Veronika Gjertsen; Guzman, Jaime; Henrey, A; Loughin, T; Glerup, Mia; Arnstad, Ellen Dalen; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan M.; Herlin, Troels; Fasth, Anders; Berntson, Lillemor; Rypdal, Martin wibe; Nordal, Ellen Berit (Journal article; Peer reviewed, 2019)
      Background Models to predict disease course and long-term outcome based on clinical characteristics at disease onset may guide early treatment strategies in juvenile idiopathic arthritis (JIA). Before a prediction model ...

    • Validation of repeated self-reported n-3 PUFA intake using serum phospholipid fatty acids as a biomarker in breast cancer patients during treatment 

      Brunvoll, Sonja Hjellegjerde; Thune, Inger; Frydenberg, Hanne; Flote, Vidar Gordon; Bertheussen, Gro Falkener; Schlichting, Ellen; Bjerve, Kristian S; Hjartåker, Anette (Journal article; Peer reviewed, 2018)
      Background The role of n-3 polyunsaturated fatty acids (PUFAs) in breast cancer is not clear and under debate. To explore this relationship it is important to have proper validated dietary assessment methods for measuring ...

    • Validity of computer-based video analysis for the assessment of postural control in individuals with cerebral palsy 

      Leirvik, Marianne Jordheim (Master thesis, 2017)
      BACKGROUND: Many studies show that individuals with cerebral palsy (CP) have problems with postural control, which is important for the ability to carry out day-to-day activities and tasks. However, there is no common ...

    • Variability Over Time of Normal-Sized Fetal Renal Pelvis During the Second Trimester Scan 

      Røset, Maria Aurora Hernandez; Blaas, Harm-Gerd Karl; Fagerli, Tove Anita; Eggebø, Torbjørn Moe (Journal article, 2017)
      Purpose To investigate the variability of the normal-sized fetal renal pelvis (≤5 mm) over time and to analyze repeatability of measurements. Materials and Methods 98 fetal renal pelvises and 49 fetal urinary bladders ...

    • Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma 

      Swaminathan, Bhairavi; Thorleifsson, Gudmar; Jöud, Magnus; Ali, Mina; Johnsson, Ellinor; Ajore, Ram; Sulem, Patrick; Halvarsson, Britt-Marie; Eyjolfsson, Gudmundur I.; Haraldsdottir, Vilhelmina; Hultman, Christina; Ingelsson, Erik; Kristinsson, Sigurdur Y; Kähler, Anna Katarina; Lenhoff, Stig; Masson, Gisli; Mellqvist, Ulf-Henrik; Månsson, Robert; Nelander, Sven; Olafsson, Isleifur; Sigurdardóttir, Olöf Gudrun; Steingrimsdottir, Hlif; Vangsted, Annette; Vogel, Ulla; Waage, Anders; Nahi, Hareth; Gudbjartsson, Daniel F.; Rafnar, Thorunn; Turesson, Ingemar; Gullberg, Urban; Stefansson, Kari; Hansson, Markus; Thorsteinsdottir, Unnur; Nilsson, Björn (Journal article; Peer reviewed, 2015)
      Multiple myeloma (MM) is characterized by an uninhibited, clonal growth of plasma cells. While first-degree relatives of patients with MM show an increased risk of MM, the genetic basis of inherited MM susceptibility is ...

    • Vascular risk factor control and adherence to secondary preventive medication after ischemic stroke 

      Gynnild, Mari Nordbø; Aakerøy, Rachel; Spigset, Olav; Askim, Torunn; Beyer, Mona Kristiansen; Ihle-Hansen, Hege; Munthe-Kaas, Ragnhild; Knapskog, Anne Brita; Lydersen, Stian; Næss, Halvor; Røsstad, Tove Garåsen; Seljeseth, Yngve Müller; Thingstad, Pernille; Saltvedt, Ingvild; Ellekjær, Hanne (Peer reviewed; Journal article, 2020)
      Background Studies regarding adequacy of secondary stroke prevention are limited. We report medication adherence, risk factor control and factors influencing vascular risk profile following ischaemic stroke. Methods A ...

    • Verbal abilities in children of mothers with epilepsy: Association to maternal folate status 

      Husebye, Elisabeth Synnøve Nilsen; Gilhus, Nils Erik; Riedel, Bettina; Spigset, Olav; Daltveit, Anne Kjersti; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2018)
      Objective To examine the effect of maternal folic acid supplementation and maternal plasma folate and antiepileptic drug (AED) concentrations on language delay in AED-exposed children of mothers with epilepsy. Methods ...

    • Verification of gene expression differences on a protein level - An IHC study 

      Skilbrigt, Ida Maria; Jensen, Sigrid Slettbakk (Master thesis, 2016)
      Background: Inflammatory bowel disease, a collective term that includes ulcerative colitis and Crohns disease, is an inflammatory disorder that affects the gastrointestinal tract, with symptoms like severe diarrea, pain, ...

    • Vision and brain in adolescents with low birth weight 

      Lindqvist, Susanne (Doktoravhandlinger ved NTNU, 1503-8181; 2009:198, Doctoral thesis, 2009)
      Premature birth and pregnancy to term, but with intrauterine growth restriction (often manifesting as birth small for gestational age, SGA, at term), both represent suboptimal environments for the developing infant brain ...

    • Visual-motor deficits relate to altered gray and white matter in young adults born preterm with very low birth weight 

      Sripada, Kam; Løhaugen, Gro; Eikenes, Live; Bjørlykke, Kjerstin Myklebust; Håberg, Asta; Skranes, Jon Sverre; Rimol, Lars Morten (Journal article; Peer reviewed, 2015)
      Individuals born preterm and at very low birth weight (birth weight ≤ 1500 g) are at an increased risk of perinatal brain injury and neurodevelopmental deficits over the long term. This study examined whether this clinical ...

    • Visuo-Motor and Visual Perceptual Impairments inYoung Adults born Preterm with Very-Low-Birth-Weight 

      Bjørlykke, Kjerstin M. (Master thesis, 2009)

    • Vitamin B6 deficiency and diseases in elderly people - a study in nursing homes 

      Kjeldby, Ida Kindsbekken; Fosnes, Gunvor Steine; Ligaarden, Solveig Catharina; Farup, Per Grønaas (Journal article; Peer reviewed, 2013)
      Background Vitamin deficiency is a cause of health related problems in elderly people. The aims were to study associations between vitamin B6 (B6) and diseases (primarily functional gastrointestinal disorders) in elderly ...

    • Vitamin B6-mangel oghelsetilstand hossykehjemspasienter 

      Kindsbekken, Ida (Master thesis, 2010)
      Bakgrunn: Sykeligheten blant sykehjemspasienter er høy, og kognitiv svikt, gastrointestinale (GI) plager og underernæring er utbredt. Vitamin B6 (B6) har en rekke funksjoner i kroppen, og er assosiert med mange ulike ...

    • Vitamin D and stress urinary incontinence in pregnancy: a cross-sectional study 

      Stafne, Signe Nilssen; Mørkved, Siv; Gustafsson, Miriam Katarina; Syversen, Unni; Stunes, Astrid Kamilla; Salvesen, Kjell Å; Johannessen, Hege Hølmo (Peer reviewed; Journal article, 2020)
      Objective To assess the association between levels of vitamin D and urinary incontinence (UI) in pregnancy. Design A cross‐sectional study. Secondary analysis of a randomised controlled trial. Setting Two university ...

    • Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease 

      Handel, Adam E; Sandve, Geir Kjetil; Disanto, Giulio; Berlanga-Taylor, Antonio; Gallone, Anna; Hanwell, Heather EC; Drabløs, Finn; Giovannoni, Gavin; Ebers, Georg C; Ramagopalan, Sreeram V (Journal article; Peer reviewed, 2013)
      Background Vitamin D insufficiency has been implicated in autoimmunity. ChIP-seq experiments using immune cell lines have shown that vitamin D receptor (VDR) binding sites are enriched near regions of the genome associated ...

    • Vitamin D status and risk of type 2 diabetes in the Norwegian HUNT cohort study: Does family history or genetic predisposition modify the association? 

      Denos, Marion; Mai, Xiao-Mei; Åsvold, Bjørn Olav; Sørgjerd, Elin Pettersen; Chen, Yue; Sun, Yi-Qian (Peer reviewed; Journal article, 2021)
      Introduction We sought to investigate the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and the risk of type 2 diabetes mellitus (T2DM) in adults who participated in the Trøndelag Health Study (HUNT), and ...