Fakultet for medisin og helsevitenskap (MH)
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Left ventricular longitudinal shortening: relation to stroke volume and ejection fraction in ageing, blood pressure, body size and gender in the HUNT3 study
(Peer reviewed; Journal article, 2020)Background: Aims of this cross-sectional study were to assess: the relative contribution of left ventricular (LV) systolic long-axis shortening (mean mitral annular plane systolic excursion, MAPSE) to stroke volume (SV), ... -
Cannabis Use during Pregnancy and Risk of Adverse Birth Outcomes: A Longitudinal Cohort Study
(Peer reviewed; Journal article, 2020)Background: With recent changes in legislation regulating recreational and medical cannabis use around the globe, increased use in pregnancy is to be expected. Objectives: To investigate the association between cannabis ... -
Pain acceptance and its impact on function and symptoms in fibromyalgia
(Peer reviewed; Journal article, 2020)Objectives Fibromyalgia is a chronic widespread pain (CWP) syndrome of unknown etiology with substantial burden of illness and functional impairment. Pain acceptance has emerged as an interesting target of therapy in ... -
Clinical and vascular responses to propranolol and candesartan in migraine patients: A randomized controlled clinical trial
(Journal article, 2020)Background: Both propranolol and candesartan are prophylactic drugs for migraine, but with unknown mechanisms of action. The objectives of the present study were to investigate these drugs’ effects on arterial wall dynamics ... -
Validation of sleep stage classification using non-contact radar technology and machine learning (Somnofy®)
(Peer reviewed; Journal article, 2020)Objective: To validate automatic sleep stage classification using deep neural networks on sleep assessed by radar technology in the commercially available sleep assistant Somnofy® against polysomnography (PSG). Methods: ... -
Mental health and health related quality of life in mitochondrial POLG disease
(Peer reviewed; Journal article, 2020)We aimed to assess the impact of POLG disease on mental health and quality of life in 15 patients using the Symptom Checklist-90-R (SCL-90-R) and Short-Form 36 Health Survey (RAND-36). We found increased scores in all nine ... -
Recovery after a stroke
(Doctoral theses at NTNU;2020:326, Doctoral thesis, 2020)Hvert år forekommer det 11-12000 hjerneslag i Norge. Disse kan variere fra små hjerneslag med kort varighet av symptomer til alvorlige slag med betydelige funksjonshemminger. De siste tiårene har andelen som overlever et ... -
The prevalence of headache disorders in children and adolescents in Ethiopia: a schools-based study
(Peer reviewed; Journal article, 2020)Background The Global Burden of Disease (GBD) study establishes headache as the second-highest cause of disability worldwide. Because most headache data in GBD are from adults, leading to underestimation of headache-attributed ... -
Oscillations in biological signal
(Doctoral theses at NTNU;2020:302, Doctoral thesis, 2020)This thesis is a study of electrocardiography, blood pressure and glucose signals in the search for oscillatory physiological processes that are of importance for resilience and the development of disease. An oscillation ... -
Zebrafish dorsal habenula is required for updating learned behaviors
(Peer reviewed; Journal article, 2020)Operant learning requires multiple cognitive processes, such as learning, prediction of potential outcomes, and decision-making. It is less clear how interactions of these processes lead to the behavioral adaptations that ... -
Population-based observational studies on intracranial hemorrhage
(Doctoral theses at NTNU;2020:308, Doctoral thesis, 2020)Populasjon- og registerbasert forskning på intrakranielle blødninger Formålet med denne doktorgradsavhandlingen var å studere ulike typer hjerneblødning i Norge. Det finnes allerede mange studier på hjerneblødning, men ... -
Multidimensional tracking of phenotypes and organ involvement in a complete nationwide systemic sclerosis cohort
(Peer reviewed; Journal article, 2020)Objective SSc is a severe, heterogeneous multi-organ disease where population-based estimates on phenotypic spectrum, overall disease burden and societal impact are largely missing. Here the objective was to provide the ... -
Robust Distance Measures for kNN Classification of Cancer Data
(Peer reviewed; Journal article, 2020)The k-Nearest Neighbor (kNN) classifier represents a simple and very general approach to classification. Still, the performance of kNN classifiers can often compete with more complex machine-learning algorithms. The core ... -
Sleep problems and depressive symptoms in toddlers and 8-year-old children: A longitudinal study
(Peer reviewed; Journal article, 2020)Sleep and depression are interlinked throughout the lifespan, but very few studies have examined the directionality of the sleep–depression link in children. The aim of the current study was to prospectively examine the ... -
Drusenoid pigment epithelial detachments and age-related macular degeneration
(Doctoral theses at NTNU;2020:328, Doctoral thesis, 2020)Patients with age-related macular degeneration (AMD) and serous or drusenoid pigment epithelial detachments (PEDs) have a high risk of progression to geographic atrophy, choroidal neovascularization, and a loss of visual ... -
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
(Peer reviewed; Journal article, 2020)Background: During atherogenesis, cholesterol precipitates into cholesterol crystals (CC) in the vessel wall, which trigger plaque inflammation by activating the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) ... -
The prevalence of headache disorders in children and adolescents in Ethiopia: a schools-based study
(Peer reviewed; Journal article, 2020)Background: The Global Burden of Disease (GBD) study establishes headache as the second-highest cause of disability worldwide. Because most headache data in GBD are from adults, leading to underestimation of headacheattributed ... -
Inflammation by pattern recognition receptors in the uterine wall decidua and the placenta of normal and preeclamptic pregnancies
(Doctoral theses at NTNU;2020:207, Doctoral thesis, 2020)Preeclampsia is a serious inflammatory disorder characterized by hypertension and proteinuria in the second half of pregnancy. It is often associated with severe maternal and fetal complications, such as fetal growth ... -
Development of strategies to identify new psychoactive substances and their metabolites in biological samples by LC-QTOF-MS technology
(Doctoral theses at NTNU;2020:303, Doctoral thesis, 2020)New psychoactive substances (NPS) are emerging in the illegal drug market, which has led to major challenges for analytical laboratories. Keeping screening methods up to date with all relevant drugs is hard to achieve and ... -
A needs assessment of resuscitative endovascular balloon occlusion of the aorta (REBOA) in non-traumatic out-of-hospital cardiac arrest in Norway
(Peer reviewed; Journal article, 2020)Introduction: Out of hospital cardiac arrest (OHCA) carries an 86% mortality rate in Norway. Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a potential adjunct in management of non-traumatic cardiac ...
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