Recent Submissions

  • Analysis of Intra-Tumoral Macrophages and T Cells in Non-Small Cell Lung Cancer (NSCLC) Indicates a Role for Immune Checkpoint and CD200-CD200R Interactions 

    Tøndell, Anders; Subbannayya, Yashwanth; Wahl, Sissel Gyrid Freim; Flatberg, Arnar; Sørhaug, Sveinung; Børset, Magne; Haug, Markus (Peer reviewed; Journal article, 2021)
    Lung cancer is the leading cause of cancer-related death worldwide, accounting for nearly one-fifth of all cancer-related deaths. Immunotherapy with immune checkpoint inhibitors has become one of the most promising approaches ...
  • Prognostic Validation of the NINDS Common Data Elements for the Radiologic Reporting of Acute Traumatic Brain Injuries: A CENTER-TBI Study 

    Vande Vyvere, Thijs; De La Rosa, Ezequiel; Wilms, Guido; Nieboer, Daan; Steyerberg, Ewout; Maas, Andrew I.R.; Verheyden, Jan; van den Hauwe, Luc; Parizel, Paul M.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe (Peer reviewed; Journal article, 2020)
    The aim of this study is to investigate the prognostic value of using the National Institute of Neurological Disorders and Stroke (NINDS) standardized imaging-based pathoanatomic descriptors for the evaluation and reporting ...
  • Physiological effects of intraperitoneal versus subcutaneous insulin infusion in patients with diabetes mellitus type 1: A systematic review and meta-analysis 

    Dirnena-Fusini, Ilze; Åm, Marte Kierulf; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Christiansen, Sverre Christian (Peer reviewed; Journal article, 2021)
    The intraperitoneal route of administration accounts for less than 1% of insulin treatment regimes in patients with diabetes mellitus type 1 (DM1). Despite being used for decades, a systematic review of various physiological ...
  • Whose voices matter? Use, misuse and non-use of augmentative and alternative communication (AAC) among severely disabled children living in small group homes. 

    Fylkesnes, Ingunn; Ytterhus, Borgunn (Peer reviewed; Journal article, 2021)
    The article explores whether and how severely disabled children living in small group homes are supported in their communicative efforts to participate and have a voice in their everyday lives. The study, framed within a ...
  • Studying the Origin of Reverberation Clutter in Echocardiography: In Vitro Experiments and In Vivo Demonstrations 

    Fatemi, Ali; Berg, Erik Andreas Rye; Rodriguez-Molares, Alfonso (Peer reviewed; Journal article, 2019)
    Clutter in echocardiography hinders the visualization of the heart and reduces the diagnostic value of the images. The detailed mechanisms that generate clutter are, however, not well understood. We present five different ...
  • Peak oxygen uptake and cardiovascular risk and disease in a healthy population 

    Letnes, Jon Magne (Doctoral theses at NTNU;2021:113, Doctoral thesis, 2021)
    SAMMENDRAG Kondisjon er vist å være en sterk risikofaktor for hjerte-karsykdom og død. Mesteparten av tidligere forskning på kondisjon som risikofaktor har vært gjennomført ved indirekte og mindre nøyaktige metoder ...
  • Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations 

    Huie, Russel J; Mondello, Stefania; Lindsell, Christopher J.; Antiga, L; Yuh, Esther; Zanier, Elisa; Masson, Serge; Rosario, Bedda; Ferguson, Adam; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Ackerlund, Cecilia; Adams, Hadie; Agnoletti, Vanni; Allanson, Judith; Amrein, Krisztina; Andaluz, Norberto; Azasevac, Antun; Antoni, Anna; Ardon, Hilko; Audibert, Gerard; Auslands, Kaspars; Azouvi, Philippe; Azzolini, Luisa; Baciu, Camelia; Badenes, Rafael; Bartels, Ronald; Barzo, Pal; Bauerfeind, Ursula; Beauvais, Romuald; Beer, Ronny; Belda, Francisco Javier; Bellander, Bo Michael; Belli, Antonio; Bellier, Remy; Benali, Habib; Benard, Thierry; Berardino, Maurizio; Beretta, Luigi; Beynon, Christopher; Bilotta, Federico; Binder, Harald; Biqiri, Erta (Peer reviewed; Journal article, 2020)
    Recent biomarker innovations hold potential for transforming diagnosis, prognostic modeling, and precision therapeutic targeting of traumatic brain injury (TBI). However, many biomarkers, including brain imaging, genomics, ...
  • Age-of-onset information helps identify 76 genetic variants associated with allergic disease 

    Ferreira, Manuel A R; Vonk, Judith M.; Baurecht, Hansjörg; Marenholz, Ingo; Tian, Chao; Hoffman, Joshua D.; Helmer, Quinta; Tillander, Annika; Ullemar, Vilhelmina; Lu, Yi; Grosche, Sarah; Ruschendorf, Franz; Granell, Raquel; Brumpton, Ben Michael; Fritsche, Lars; Bhatta, Laxmi; Gabrielsen, Maiken Elvestad; Nielsen, Jonas Bille; Zhou, Wei; Hveem, Kristian; Langhammer, Arnulf; Holmen, Oddgeir; Løset, Mari; Abecasis, Goncalo; Willer, Cristen J.; Emami, Nima C.; Cavazos, Taylor B.; Witte, John S.; Szwajda, Agnieszka; 23andMe Research Team, ,; collaborators of SHARE study, ,; Hinds, David A.; Hubner, Norbert; Weidinger, Stephan; Magnusson, Patrik KE; Jorgenson, Eric; Karlsson, Robert; Paternoster, Lavinia; Boomsma, Dorret I.; Almqvist, Catarina; Lee, Young-Ae; Koppelman, Gerard H.; Esparza-Gordillo, Jorge; Hummel, Oliver; Hottenga, Jouke-Jan; Willemsen, Gonneke; Rodríguez, Elke; Hotze, Melanie; Franke, Andre; Matheson, Melanie C.; Dharmage, Shyamali Chandrika; Arnold, Andreas; Homuth, Georg; Schmidt, Carsten O; Thompson, Philip J.; Martin, Nicholas G; Duffy, David L.; Novak, Natalija; Schulz, Holger; Karrasch, Stefan; Gieger, Christian; Strauch, Konstantin; Melles, Ronald B (Peer reviewed; Journal article, 2020)
    Risk factors that contribute to inter-individual differences in the age-of-onset of allergic diseases are poorly understood. The aim of this study was to identify genetic risk variants associated with the age at which ...
  • Comparison of Muscle Activity in Three Single-Joint, Hip Extension Exercises in Resistance-Trained Women 

    Andersen, Vidar; Pedersen, Helene; Fimland, Marius Steiro; Shaw, Matthew Peter; Solstad, Tom Erik Jorung; Stien, Nicolay; Cumming, Kristoffer Toldnes; Sæterbakken, Atle Hole (Peer reviewed; Journal article, 2021)
    The aim of the study was to compare neuromuscular activation in the gluteus maximus, the biceps femoris and the erector spinae from the Romanian deadlift, the 45-degree Roman chair back extension and the seated machine ...
  • Continuous subcutaneous infusion for pain control in dying patients: experiences from a tertiary palliative care center 

    Fürst, Per; Lundström, Staffan; Klepstad, Pål; Strang, Peter (Peer reviewed; Journal article, 2020)
    Background Continuous subcutaneous infusion (CSCI) via ambulatory infusion pump (AIP) is a valuable method of pain control in palliative care. When using CSCI, low-dose methadone as add-on to other opioids might be an ...
  • Ethiopian Health Care Workers’ Insights into and Responses to Intimate Partner Violence in Pregnancy—A Qualitative Study 

    Gashaw, Bosena Tebeje; Schei, Berit; Solbrække, Kari Nyheim; Magnus, Jeanette H. (Peer reviewed; Journal article, 2020)
    Violence against women is a global pandemic, with the potential to spread through generations. Intimate partner violence has impacts on women’s sexual, reproductive, and psycho-social health. It can occur during pregnancy ...
  • Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity-A Randomized Controlled Trial 

    Berge, Jarle; Hjelmesæth, Jøran; Hertel, Jens Kristoffer; Gjevestad, Espen Svendsen; Småstuen, Milada Cvancarova; Johnson, Line Kristin; Martins, Catia; Andersen, Eivind; Helgerud, Jan; Støren, Øyvind (Peer reviewed; Journal article, 2021)
    Objective This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure. Methods This was a single‐center randomized controlled trial of patients with severe obesity ...
  • Retrospective Transmit beamforming and Coherent Plane-Wave Compounding for Microvascular Doppler Imaging: A Comparison Study 

    Golfetto, Cristiana; Ekroll, Ingvild Kinn; Torp, Hans; Løvstakken, Lasse; Avdal, Jørgen (Peer reviewed; Journal article, 2020)
    Imaging blood flow in small vessels is of great clinical value for evaluating increased vascularization, potentially related to angiogenesis in cancer or inflammation processes in musculoskeletal disease. Using a traditional ...
  • Does a history of cardiovascular disease or cancer affect mortality after SARS-CoV-2 infection? 

    Kvåle, Rune; Bønaa, Kaare Harald; Forster, Rachel Bedenis; Gravningen, Kirsten Midttun; Juliusson, Pétur Benedikt; Myklebust, Tor Åge (Peer reviewed; Journal article, 2021)
    BAKGRUNN Hjerte- og karsykdommer og kreft har vært beskrevet som mulige risikofaktorer for død av covid-19. Hensikten med studien er å undersøke om tidligere påvist hjerte- og karsykdom eller kreft har påvirket risiko for ...
  • Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium 

    Hansen, Jan; Kaiser, Fabian; Klausen, Christina; Stüven, Birthe; Chong, Raymond; Bönigk, Wolfgang; Mick, David; Möglich, Andreas; Jurisch-Yaksi, Nathalie; Schmidt, Florian; Wachten, Dagmar (Peer reviewed; Journal article, 2020)
    Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ...
  • The cost-effectiveness of treatments for attention deficit-hyperactivity disorder and autism spectrum disorder in children and adolescents: a systematic review 

    Sampaio, Filipa; Feldman, Inna; Lavelle, Tara A.; Skokauskas, Norbert (Peer reviewed; Journal article, 2021)
    Economic evaluations can help decision makers identify what services for children with neurodevelopmental disorders provide best value-for-money. The aim of this paper is to review the best available economic evidence to ...
  • Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients 

    Colombo, Francesca; Pintarelli, Giulia; Galvan, Antonella; Noci, Sara; Corli, Oscar; Skorpen, Frank; Klepstad, Pål; Kaasa, Stein; Pigni, Alessandra; Brunelli, Cinzia; Roberto, Anna; Piazza, Rocco; Pirola, Alessandra; Gambacorti-Passerini, Carlo; Caraceni, Augusto Tomasso Giovanni (Peer reviewed; Journal article, 2020)
    Nausea and vomiting are often associated with opioid analgesia in cancer patients; however, only a subset of patients develop such side effects. Here, we tested the hypothesis that the occurrence of nausea and vomiting is ...
  • Patients with Fibromyalgia and Chronic Fatigue Syndrome show increased hsCRP compared to healthy controls 

    Groven, Nina; Fors, Egil Andreas; Reitan, Solveig Merete Klæbo (Peer reviewed; Journal article, 2019)
    Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM) are both chronic disorders that have a devastating effect on the lives of the affected patients and their families. Both conditions have overlapping clinical features ...
  • Elder abuse in Norwegian nursing homes: Prevalence and risk factors 

    Botngård, Anja (Doctoral theses at NTNU;2021:116, Doctoral thesis, 2021)
    Norsk sammendrag Bakgrunn: Vold, overgrep og forsømmelser mot eldre er et alvorlig folkehelse- og menneskerettighetsproblem som forventes å øke i takt med den økende andelen eldre i befolkningen. Slike uønskede hendelser ...
  • Impact of Antithrombotic Agents on Radiological Lesion Progression in Acute Traumatic Brain Injury: A CENTER-TBI Propensity-Matched Cohort Analysis 

    Mathieu, Francois; Güting, Helge; Gravesteijn, Benjamin; Monteiro, Miguel; Glocker, Ben; Kornaropoulos, Evgenios; Kamnistas, Konstantinos; Robertson, Claudia; Levin, Harvey; Whitehouse, Daniel; Das, Tilak; Lingsma, Hester F; Maegele, Marc; Newcombe, Virginia F.J.; Menon, David K; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa (Peer reviewed; Journal article, 2020)
    An increasing number of elderly patients are being affected by traumatic brain injury (TBI) and a significant proportion are on pre-hospital antithrombotic therapy for cardio- or cerebrovascular indications. We have ...

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