Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1136-1155 of 3426
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Expression of estrogen receptor-α and survival in advanced-stage non-small cell lung cancer
(Journal article; Peer reviewed, 2018)Background/Aim: The favorable prognosis of women with non-small-cell lung cancer (NSCLC) compared to men might be explained by sex hormone-related mechanisms. We investigated whether this observation could be explained by ... -
Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients
(Journal article; Peer reviewed, 2017)Background: Several studies have identified L1 cell adhesion molecule (L1CAM) as a strong prognostic marker in endometrial cancer. To further underline the clinical usefulness of this biomarker, we investigated L1CAM as ... -
Expression of Multidrug Reisistance Protein ABCB1 and Drug Sensitivity in Carfilzomib Resistant Myeloma Cell Lines
(Master thesis, 2021)Myelomatose/beinmargskreft er den andre mest vanlige hematologiske sykdommen i verden, og er en krefttype som kommer av ukontrollert vekst av plasmaceller i beinmargen. Det finnes foreløpig ingen kurerende behandling, ... -
Expression of PPARγ in inflammatory bowel disease: a role in regulating colonic inflammation
(Master thesis, 2017)Background: Inflammatory bowel disease (IBD) is a collective term for the two entities, ulcerative colitis (UC) and Crohn’s disease (CD). They are both characterized by a relapsing inflammation causing destruction of the ... -
Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells
(Journal article, 2017)Gastric cancer is an important disease due to its high mortality. Despite the decline in frequency, most cases are discovered late in its course, and most of the cancer patients die within a few years of diagnosis. In ... -
The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
(Peer reviewed; Journal article, 2020)The long non-coding RNA NEAT1 locus is transcribed into two overlapping isoforms, NEAT1_1 and NEAT1_2, of which the latter is essential for the assembly of nuclear paraspeckles. NEAT1 is abnormally expressed in a wide ... -
Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2
(Journal article; Peer reviewed, 2013)Anti-microbial peptides might influence the pathogenesis and course of inflammatory bowel disease (IBD). We sought to clarify the role of the anti-microbial glycoprotein lipocalin 2 (LCN2) in the colon by determining its ... -
Expression of Transforming growth factor beta in Breast Cancer Subtypes
(Master thesis, 2017)Background: Normally, transforming growth factor beta (TGF-b) functions as a tumorsuppressor. But, during carcinogenesis, malignant cells become insensitive to TGF-b´s growth inhibitory abilities, and the traits of TGF-b ... -
Expression of β-Catenin, E-Cadherin, and α-Smooth Muscle Actin in Basal Cell Carcinoma Before Photodynamic Therapy in Non-recurrent and Recurrent Tumors: Exploring the Ability of Predicting Photodynamic Therapy outcome
(Peer reviewed; Journal article, 2023)Photodynamic therapy (PDT) is an effective and cosmetically beneficial treatment of low-risk basal cell carcinomas (BCCs). To optimize PDT response, it is important to correctly select tumors. We sought to find markers ... -
External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis
(Peer reviewed; Journal article, 2020)Background Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk during pregnancy is required to plan management. Although there are many published ... -
External validity of the Both Hands Assessment for evaluating bimanual performance in children with bilateral cerebral palsy
(Peer reviewed; Journal article, 2021)Aim To investigate the external validity of the Both Hands Assessment (BoHA), a new test evaluating bimanual performance in children with bilateral cerebral palsy (CP), by analysing its relationship to established ... -
Extracorporeal photochemotherapy in patients with Cutaneous T Cell Lymphomaor Graft-vs-Host Disease
(Doktoravhandlinger ved NTNU, 1503-8181; 2009:236, Doctoral thesis, 2009)Extracorporeal photokjemoterapi (ECP) har blitt akseptert som behandling av enkelte T celle medierte tilstander, som kutant T celle lymfom (CTCL) og Graft-vs-Host disease (GVHD). Ved CTCL responderer omtrent halvparten av ... -
Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review
(Peer reviewed; Journal article, 2022)Outer space is an extremely hostile environment for human life, with ionizing radiation from galactic cosmic rays and microgravity posing the most significant hazards to the health of astronauts. Spaceflight has also been ... -
Factors affecting quality of end-of-life hospital care - a qualitative analysis of free text comments from the i-CODE survey in Norway
(Peer reviewed; Journal article, 2020)Background The ERANet-LAC CODE (Care Of the Dying Evaluation) international survey assessed quality of care for dying cancer patients in seven countries, by use of the i-CODE questionnaire completed by bereaved relatives. ... -
Factors Associated with Enhanced Gross Motor Progress in children with Cerebral Palsy: A Register-based Study
(Journal article; Peer reviewed, 2018)Aim: To examine associations between interventions and child characteristics; and enhanced gross motor progress in children with cerebral palsy (CP). Methods: Prospective cohort study based on 2048 assessments of 442 ... -
Factors associated with internalizing or somatic symptoms in a cross-sectional study of school children in grades 1-10
(Journal article; Peer reviewed, 2010)Background: School related factors that may contribute to children’s subjective health have not been extensively studied. We assessed whether factors assumed to promote health and factors assumed to have adverse effects were ... -
Factors associated with subjective burden among informal caregivers of home-dwelling people with dementia: a cross-sectional study
(Peer reviewed; Journal article, 2023)Background It is estimated that more than 57 million people have dementia worldwide, and it is one of the leading causes of care dependency in old age. Relatives and other informal caregivers are the most important support ... -
Factors associated with the persistence of oral 5-aminosalicylic acid monotherapy in ulcerative colitis: a nationwide Norwegian cohort study
(Journal article; Peer reviewed, 2021)Background: Oral 5-aminosalicylic acid (5-ASA) is the mainstay treatment of ulcerative colitis (UC) and therapy with oral 5-ASA is associated with beneficial outcomes. We have examined factors associated with the persistence ... -
Factors associated with time to pregnancy in women with axial spondyloarthritis: A registry-based multicenter study
(Peer reviewed; Journal article, 2020)Objective To study time to pregnancy (TTP) and factors associated with TTP in women with axial spondyloarthritis (axSpA), compared to women with rheumatoid arthritis (RA). Methods We included 274 women with axSpA and ... -
Factors associated with trace evidence analyses and DNA findings among police reported cases of rape
(Journal article; Peer reviewed, 2017)Objective The aim of this study was to examine the association between victim, suspect and assault characteristics and (1) forensic analysis of trace evidence, (2) detection of spermatozoa and (3) DNA match in police-reported ...