Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 543-562 of 3430
-
Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements
(Journal article; Peer reviewed, 2011)Background Transcription factor binding to DNA requires both an appropriate binding element and suitably open chromatin, which together help to define regulatory elements within the genome. Current methods of identifying ... -
ClusTrack: Feature extraction and similarity measures for clustering of genome-wide data sets
(Journal article, 2015)Clustering is a popular technique for explorative analysis of data, as it can reveal subgroupings and similarities between data in an unsupervised manner. While clustering is routinely applied to gene expression data, there ... -
Co-medication among patients diagnosed with Crohn’s disease – an observational health register study.
(Master thesis, 2022)Abstract will be available on 2027-05-31 -
Co-prescription of metoprolol and CYP2D6-inhibiting antidepressants before and after implementation of an optimized drug interaction database in Norway
(Journal article; Peer reviewed, 2022) -
Co-Use of Drugs and Herbal Remedies in General Practice and In Vitro Inhibition of CYP3A4, CYP2D6 and P-Glycoprotein by the Common Herb Aloe Vera.
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:333, Doctoral thesis, 2013)There is a widespread use of complementary and alternative medicine (CAM) and herbal remedies in particular in different patients groups, but very few are published about co-use among patients in general practice (GP) and ... -
Coactivation of TLR2 and TLR8 in Primary Human Monocytes Triggers a Distinct Inflammatory Signaling Response
(Journal article; Peer reviewed, 2018)Innate immune signaling is essential to mount a fast and specific immune response to pathogens. Monocytes and macrophages are essential cells in the early response in their capacity as ubiquitous phagocytic cells. They ... -
Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology
(Peer reviewed; Journal article, 2022)Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase ... -
Coeliac disease in the Trøndelag Health Study (HUNT), Norway, a population-based cohort of coeliac disease patients
(Peer reviewed; Journal article, 2024)Purpose - Coeliac disease (CD) is a common disorder and affects about 1% of the population worldwide. CD in the Trøndelag Health Study (HUNT) is a population-based cohort study which was established to provide new knowledge ... -
Cognitive deficits associated with impaired awareness of hypoglycaemia in type 1 diabetes
(Journal article; Peer reviewed, 2017)Aims/hypothesis The aim of this study was to compare cognitive function in adults with type 1 diabetes who have impaired awareness of hypoglycaemia with those who have normal awareness of hypoglycaemia. A putative ... -
Cognitive function during disease progression in a rat model of Alzheimer’s disease - Effect of a single bout of exhaustive aerobic exercise
(Master thesis, 2018)Alzheimer’s disease (AD), the most prevalent form of dementia, is a devastating neurodegenerative disorder affecting over 35 million people worldwide. As age is the main risk factor for AD, and no current treatment options ... -
Cognitive function in metformin exposed children, born to mothers with PCOS – follow-up of an RCT
(Journal article; Peer reviewed, 2020)Background Metformin is widely used in pregnancy to treat gestational diabetes mellitus and polycystic ovary syndrome (PCOS). Association between PCOS and developmental delay in offspring, and larger head circumference ... -
Cognitive Function, Mental Health, and Quality of Life in Siblings of Preterm Born Children: Protocol for a Systematic Review
(Peer reviewed; Journal article, 2022)Background: Children and adults born preterm are at increased risk of cognitive impairments, mental health disorders, and poorer quality of life. Epidemiological studies have shown that the impact of preterm birth extends ... -
Cognitive impairment in minor Stroke An observational study of the prevalence of cognitive impairment and emotional symptoms and consequences for social functioning and employment
(Doctoral theses at NTNU;2020:320, Doctoral thesis, 2020)Hjerneslag rammer årlig ca 12 000 personer i Norge og er en av de hyppigste årsaker til invaliditet. Data fra Norsk hjerneslagregister viser at 2/3 av pasientene blir selvhjulpne etter et hjerneslag. En betydelig andel av ... -
Cognitive Profiles and Atrophy Ratings on MRI in Senior Patients With Mild Cognitive Impairment
(Journal article; Peer reviewed, 2018)In this cross-sectional study, we sought to describe cognitive and neuroimaging profiles of Memory clinic patients with Mild Cognitive Impairment (MCI). 51 MCI patients and 51 controls, matched on age, sex, and socio-economic ... -
Cognitive Rehabilitation for Neurocognitive Late Effects in Adult Survivors of Childhood Acute Lymphoblastic Leukemia: A Feasibility and Case-Series Study
(Peer reviewed; Journal article, 2021)Neurocognitive late effects following the diagnosis and treatment of childhood acute lymphoblastic leukemia (ALL) commonly include impaired executive functions (EFs), with negative consequences for one’s health-related ... -
Cognitive rehabilitation in paediatric acquired brain injury—A 2-year follow-up of a randomised controlled trial
(Peer reviewed; Journal article, 2023)Background: Goal management training (GMT), a metacognitive rehabilitation method that has been demonstrated to improve executive function (EF) in adults with acquired brain injury (ABI), could potentially be effective for ... -
Cognitive Trajectories in Older Patients with Cancer Undergoing Radiotherapy—A Prospective Observational Study
(Peer reviewed; Journal article, 2022)Cognitive function can be affected by cancer and/or its treatment, and older patients are at a particular risk. In a prospective observational study including patients ≥65 years referred for radiotherapy (RT), we aimed to ... -
A Cohort Study on Cancer Incidence among Women Exposed to Environmental Asbestos in Childhood with a Focus on Female Cancers, including Breast Cancer
(Peer reviewed; Journal article, 2022)Objectives: To examine the risk of cancer in former school children exposed to environmental asbestos in childhood with a focus on female cancers, including breast cancer. Methods: We retrieved a cohort of females (n = ... -
COL11A1 is associated with developmental dysplasia of the hip and secondary osteoarthritis in the HUNT study
(Peer reviewed; Journal article, 2023)Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ... -
Cold agglutinin disease revisited: a multinational, observational study of 232 patients
(Peer reviewed; Journal article, 2020)We retrospectively studied 232 patients with cold agglutinin disease (CAD) at 24 centers in 5 countries. In Norway and a northern region of Italy, the study was close to being population-based. For the first time, we ...