Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 517-536 of 3430
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Chronic pain in the general population: Measurement, burden and associations with physical activity: – The HUNT pain study –
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:148, Doctoral thesis, 2013) -
Chronic vulvar pain in gynecological outpatients
(Peer reviewed; Journal article, 2022)Objectives Chronic vulvar pain (CVP) is pain in the vulvar area exceeding three months of duration. Previous studies have reported a prevalence of 7–8% in the general population and observed an association between CVP and ... -
Chronic wounds in sierra leone: Searching for buruli ulcer, a ntd caused by mycobacterium ulcerans, at masanga hospital
(Peer reviewed; Journal article, 2021)Chronic wounds constitute a significant surgical burden to low- and middle-income countries; however, their aetiology often remains poorly understood. This study improves our understanding of wound aetiology through tissue ... -
CImbinator: a web-based tool for drug synergy analysis in small- and large-scale datasets
(Journal article; Peer reviewed, 2017)Motivation: Drug synergies are sought to identify combinations of drugs particularly beneficial. User-friendly software solutions that can assist analysis of large-scale datasets are required. Results: CImbinator is a ... -
Circulating and Adipose Tissue miRNAs in Women With Polycystic Ovary Syndrome and Responses to High-Intensity Interval Training
(Peer reviewed; Journal article, 2020)MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression post-transcriptionally. In women with polycystic ovary syndrome (PCOS), several miRNAs are differentially expressed compared to women without PCOS, ... -
Circulating calprotectin: from measurement to clinical application - studies of preanalytical, analytical, and cardiovascular biomarker performance
(Doctoral theses at NTNU;2024:161, Doctoral thesis, 2024)Norsk sammendrag Hjerte-karsykdom er en svært vanlig årsak til sykdom og tidlig død på verdensbasis og skyldes i hovedsak åreforkalkning (aterosklerose) som oppstår pga. fettavleiringer og inflammasjon i åreveggene. ... -
Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia
(Peer reviewed; Journal article, 2022)Preeclampsia (PE) generally manifests in the second half of pregnancy with hypertension and proteinuria. The understanding of the origin and mechanism behind PE is incomplete, although there is clearly an immune component ... -
Circulating levels of micronutrients and risk of infections: a Mendelian randomization study
(Peer reviewed; Journal article, 2023)Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections. Previous observational studies and randomized ... -
Circulating Lipoproteins in Subjects with Morbid Obesity Undergoing Bariatric Surgery with Gastric Bypass or Sleeve Gastrectomy
(Peer reviewed; Journal article, 2022)The efficacy of various bariatric procedures on the mitigation of the obese dyslipidemia remains debated, and the impact of these measures on lipoprotein(a) (Lp(a)) levels is unknown. In this study we aimed to compare the ... -
Circulating microRNAs May Serve as Biomarkers for Hypertensive Emergency End-Organ Injuries and Address Underlying Pathways in an Animal Model
(Journal article; Peer reviewed, 2021)There is an incomplete understanding of the underlying pathophysiology in hypertensive emergencies, where severely elevated blood pressure causes acute end-organ injuries, as opposed to the long-term manifestations of ... -
Claims for compensation from gynecological patients - what can we learn?
(Doctoral theses at NTNU;2021:327, Doctoral thesis, 2021) -
Claims for compensation from women with cervical cancer in Norway-A retrospective, descriptive study of a 12-year period
(Peer reviewed; Journal article, 2020)Introduction: In Norway, all patient-reported claims for compensation are evaluated by The Norwegian System of Patient Injury Compensation (NPE). The number of claims from women with cervical cancer is rising, and the ... -
Classification and biomarker identification of prostate tissue from TRAMP mice with hyperpolarized 13C-SIRA
(Peer reviewed; Journal article, 2021)Hyperpolarized 13C isotope resolved spectroscopy boosts NMR signal intensity, which improves signal detection and allows metabolic fluxes to be analyzed. Such hyperpolarized flux data may offer new approaches to tissue ... -
Classification of Common Food Lipid Sources Regarding Healthiness Using Advanced Lipidomics: A Four-Arm Crossover Study
(Journal article; Peer reviewed, 2023) -
Clinical Aspects in Translational Research on Gastric Tumorigenesis and Development of New Treatments
(Doctoral theses at NTNU;2023:360, Doctoral thesis, 2023)Kliniske aspekter ved translasjonsforskning på magekreft og utvikling av nye behandlinger Bakgrunn/mål: Medisinsk translasjonsforskning er en toveis prosess for å redusere avstanden fra laboratoriet til sykesengen ved å ... -
Clinical aspects of a nationwide epidemic of severe haemolytic uremic syndrome (HUS) in children
(Journal article; Peer reviewed, 2011)Background: Report a nationwide epidemic of Shiga toxin-producing E. coli (STEC) O103:H25 causing hemolytic uremic syndrome (D+HUS) in children. Methods: Description of clinical presentation, complications and outcome ... -
Clinical phenotypes and long-term prognosis in white patients with biopsy-verified hypertensive nephrosclerosis
(Peer reviewed; Journal article, 2020)Introduction Hypertensive nephrosclerosis is considered the second most common cause of end-stage renal disease (ESRD), but it is still an insufficiently studied and controversial disease entity. More information on the ... -
Clinical Predictors for Analgesic Response to Radiotherapy in Patients with Painful Bone Metastases
(Peer reviewed; Journal article, 2021)Background Radiotherapy (RT) reduces pain in about 60% of patients with painful bone metastases, leaving many patients without clinical benefit. This study assesses predictors for RT effectiveness in patients with painful ... -
A clinical prognostic scoring system for resectable gastric cancer to predict survival and benefit from paclitaxel- or oxaliplatin-based adjuvant chemotherapy
(Peer reviewed; Journal article, 2016)Background: Gastrectomy with D2 lymphadenectomy is a standard procedure of curative resection for gastric cancer (GC). The aim of this study was to develop a simple and reliable prognostic scoring system for GC treated ... -
Clinical research in end-of-life cancer care Current status, barriers, priorities, and a framework for reporting a sample in clinical trials
(Doctoral thesis at NTNU;2014:355, Doctoral thesis, 2014)Kreft er en av de vanligste dødsårsakene i verden og den globale forekomsten øker. Mange pasienter som dør av kreft, har behov for palliative tiltak, men bare en liten andel av midlene til kreftforskning fordeles til ...