Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 279-298 av 3426
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Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia
(Journal article; Peer reviewed, 2019)Background The majority of patients with advanced cancer develop cachexia, a weight loss syndrome that severely reduces quality of life and limits survival. Our understanding of the underlying mechanisms that cause the ... -
Automated machine learning optimizes and accelerates predictive modeling from COVID-19 high throughput datasets
(Peer reviewed; Journal article, 2021)COVID-19 outbreak brings intense pressure on healthcare systems, with an urgent demand for effective diagnostic, prognostic and therapeutic procedures. Here, we employed Automated Machine Learning (AutoML) to analyze three ... -
Automated Quantification of Human Osteoclasts Using Object Detection
(Peer reviewed; Journal article, 2022)A balanced skeletal remodeling process is paramount to staying healthy. The remodeling process can be studied by analyzing osteoclasts differentiated in vitro from mononuclear cells isolated from peripheral blood or from ... -
Automatic Detection and Measurement of Fetal Biparietal Diameter and Femur Length — Feasibility on a Portable Ultrasound Device
(Journal article, 2017)An automatic method able to recognize a presented section through the biparietal plane of the fetal head and a section through the fetal femur in ultrasound images is developed. Once the correct anatomical section for ... -
Autophagy as a Survival Mechanism or a Cause of Disease
(Doctoral thesis at NTNU;2016:52, Doctoral thesis, 2016)Proper turnover of cellular components is crucial for all cells. If damaged or excessive content in the cell is not removed at a sufficient pace, normal cell functions may be compromised. The same may occur if the ... -
Autopsy findings of central nervous system anomalies in intact fetuses following termination of pregnancy after prenatal ultrasound diagnosis
(Journal article; Peer reviewed, 2019)Objectives Central nervous system (CNS) anomalies are the second most frequent category of congenital anomalies after congenital heart defects (CHDs). In this study, the aim was to investigate the distribution of different ... -
Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation
(Peer reviewed; Journal article, 2020)Background In vitro, the complement system can be studied in test tubes incubated with anticoagulated human whole-blood. Background activation of complement may mask inflammatory signals. Air bubbles are known to activate ... -
Avvikshåndtering - noe å lære av? En kvalitativ studie av enhets- og avdelingslederes tanker og erfaringer
(Master thesis, 2021)Bakgrunn Bakgrunnen for denne masteroppgaven er å undersøke hvilke erfaringer ledere har med å håndtere legemiddelhåndteringsavvik i primærhelsetjenesten. Dagens legemiddelbrukere i primærhelsetjenesten lever lengre med ... -
Awareness of cervical cancer and prevalence of human papillomavirus and other sexually transmitted infections among women in rural Nepal.: Implications for future cervical cancer prevention in Nepal
(Doctoral theses at NTNU;2017:87, Doctoral thesis, 2017)Cervical cancer is a leading cause of cancer deaths among women in Nepal. Limited information is available on public awareness on cervical cancer, the prevalence of its causative agents and associated risk factors. No ... -
Awareness of hypoglycemia in type 1 diabetes - On the assessment, prevalence, and clinical associations of impaired awareness of hypoglycemia in children and adults
(Doctoral theses at NTNU;2023:408, Doctoral thesis, 2023)Over one hundred years after the first doses of insulin were given as treatment for type 1 diabetes (TlD), hypoglycemia is still the main factor limiting optimal blood glucose control. Episodes of hypoglycemia are by itself ... -
Awareness of polycystic ovary syndrome among obstetrician-gynecologists and endocrinologists in Northern Europe.
(Journal article; Peer reviewed, 2019)Objective To date, little is known about differences in the knowledge, diagnosis making and treatment strategies of health care providers regarding polycystic ovary syndrome (PCOS) across different disciplines in countries ... -
Backbone 1H, 13C and 15N chemical shift assignment of full-length human uracil DNA glycosylase UNG2
(Journal article; Peer reviewed, 2017)Human uracil N-glycosylase isoform 2—UNG2 consists of an N-terminal intrinsically disordered regulatory domain (UNG2 residues 1–92, 9.3 kDa) and a C-terminal structured catalytic domain (UNG2 residues 93–313, 25.1 kDa). ... -
Bacterial Load in Daily Urine Samples of Patients Infected with Mycoplasma genitalium, Mutation Analysis, and Response to Treatment
(Peer reviewed; Journal article, 2016)Objective. Increasing macrolide resistant strains of Mycoplasma genitalium is a challenge, and to differentiate between treatment failure and reinfection a timely test of cure (TOC) is warranted. The aim of this study was ... -
Bacterial secretion systems and regulation of inflammasome activation
(Journal article, 2017)Innate immunity is critical for host defenses against pathogens, but many bacteria display complex ways of interacting with innate immune signaling, as they may both activate and evade certain pathways. Gram‐negative ... -
Bariatric surgery versus lifestyle interventions for severe obesity: 5-year changes in body weight, risk factors and comorbidities
(Journal article; Peer reviewed, 2017)Changes in body weight (BW), risk factors and comorbidities 5 years after Roux-en-Y gastric bypass (RYGB) or different lifestyle interventions are compared. A total of 209 (75% women) severe obese adults were non-randomly ... -
Barn med overvekt og fedme: en kvantitativ pilotstudie av standardisert livsstilsbehandling i kommunehelsetjenesten
(Peer reviewed; Journal article, 2021)Hensikt: De fleste barn med overvekt og fedme behandles i kommunehelsetjenesten, men virkning av behandlingstiltak i norske kommuner er ikke publisert. Målet med denne pilotstudien var å undersøke den relative vektnedgangen ... -
Barnevaksinasjonsprogrammet i Norge. Rapport for 2019 og 2020.
(Barnevaksinasjonsprogrammet i Norge;, Research report, 2021)Barnevaksinasjonsprogrammet 2019-2020 Barnevaksinasjonsprogrammet omfatter en rekke ulike vaksiner som helsemyndighetene anbefaler til barn og unge, og tilbys alle barn og unge som oppholder seg i Norge. I 2019 og 2020 ... -
Barnevaksinasjonsprogrammet i Norge. Rapport for 2021
(Barnevaksinasjonsprogrammet i Norge;, Research report, 2022)Barnevaksinasjonsprogrammet 2021 Barnevaksinasjonsprogrammet omfatter en rekke ulike vaksiner som helsemyndighetene anbefaler til barn og unge, og tilbys alle barn og unge som oppholder seg i Norge. I 2021 ble vaksiner ... -
Barriers to and facilitators for implementing quality improvements in palliative care – results from a qualitative interview study in Norway
(Journal article; Peer reviewed, 2016)Background: Implementation of quality improvements in palliative care (PC) is challenging, and detailed knowledge about factors that may facilitate or hinder implementation is essential for success. One part of the ... -
Barriers to increase surgical productivity in Sierra Leone: A qualitative study
(Peer reviewed; Journal article, 2021)Objective To explore factors influencing surgical provider productivity and identify barriers against and opportunities to increase individual surgical productivity in Sierra Leone, in order to explain the observed increase ...