Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 2550-2569 av 3429
-
Prognostic value of ErbB2/HER2 in human meningiomas
(Journal article; Peer reviewed, 2018)Introduction Among clinical challenges regarding human meningiomas is their propensity to recur even in cases with benign histology. Reliable biomarkers that can identify these cases are therefore highly desired. ErbB2/HER2 ... -
Prognostic value of Ki-67/MIB-1 labeling index in human meningiomas - a review of theliterature
(Master thesis, 2009) -
The prognostic value of KRAS in circulating cell-free DNA and tumour tissue in patients with non-small cell lung cancer
(Doctoral theses at NTNU;2021:315, Doctoral thesis, 2021) -
Prognostic value of metabolic response in breast cancer patients receiving neoadjuvant chemotherapy
(Journal article; Peer reviewed, 2012)Background Today's clinical diagnostic tools are insufficient for giving accurate prognosis to breast cancer patients. The aim of our study was to examine the tumor metabolic changes in patients with locally advanced breast ... -
The prognostic value of methylation signatures and NF2 mutations in atypical meningiomas
(Peer reviewed; Journal article, 2021)Background: Due to the solely subjective histopathological assessment, the WHO 2016 classification of human meningiomas is subject to interobserver variation. Consequently, the need for more reliable and objective markers ... -
Prognostic Value of Post First-Line Chemotherapy Glasgow Prognostic Score in Advanced Non-Small Cell Lung Cancer
(Peer reviewed; Journal article, 2022)Background: The Glasgow prognostic score (GPS) is an established inflammatory prognostic index in cancer patients. Most studies have only measured GPS at baseline (B-GPS). Effective cancer therapy may reduce inflammation, ... -
The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy—The Randomized NORDIC9-Study
(Peer reviewed; Journal article, 2022)Appropriate patient selection for palliative chemotherapy is crucial in patients with metastatic colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP), derived neutrophil-to-lymphocyte ... -
Progressive multifocal leukoencephalopathy in an immunocompetent patient?
(Peer reviewed; Journal article, 2013)Background: Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive, potentially fatal, demyelinating disease affecting immunosuppressed patients. PML is rarely reported in cases with no underlying disease ... -
Prolactin and breast increase during pregnancy in PCOS: linked to long-term metabolic health?
(Journal article; Peer reviewed, 2019)Objective To explore whether gestational prolactin and breast increase are markers of metabolic health in pregnancy and on long-term, in PCOS. Design Follow-up study. Women with PCOS, according to the Rotterdam criteria ... -
Proliferation in molecular subtypes of breast cancer
(Doctoral theses at NTNU;2023:30, Doctoral thesis, 2023)Breast cancer is a heterogeneous disease. Using immunohistochemistry (IHC) and in situ hybridization (ISH) breast cancers can be divided into molecular subtypes with different prognosis and response to treatment. Increased ... -
Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells
(Journal article; Peer reviewed, 2013)Background Cigarette smoking is the major risk factor for COPD, leading to chronic airway inflammation. We hypothesized that cigarette smoke induces structural and functional changes of airway epithelial mitochondria, ... -
Properdin binding to complement activating surfaces depends on initial C3b deposition
(Journal article; Peer reviewed, 2017)Two functions have been assigned to properdin; stabilization of the alternative convertase, C3bBb, is well accepted, whereas the role of properdin as pattern recognition molecule is controversial. The presence of ... -
Prospective longitudinal MRI study of brain volumes and diffusion changes during the first year after moderate to severe traumatic brain injury
(Journal article, 2014)The objectives of this prospective study in 62 moderate–severe TBI patients were to investigate volume change in cortical gray matter (GM), hippocampus, lenticular nucleus, lobar white matter (WM), brainstem and ventricles ... -
A prospective observational study comparing two supraglottic airway devices in out-of-hospital cardiac arrest
(Journal article; Peer reviewed, 2021)Background: Airway management in patients with out of hospital cardiac arrest (OHCA) is important and several methods are used. The establishment of a supraglottic airway device (SAD) is a common technique used during OHCA. ... -
Prostate Cancer – Translational Research: Optimizing tissue sampling suitable for histopathologic, transcriptomic and metabolic profiling
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:240, Doctoral thesis, 2012)Prostate cancer (PCa) is the most common cancer in men in Europe and constitutes a substantial health care problem. In 2009, 4299 new cases were diagnosed in Norway and PCa was the second most common cause of death from ... -
Prostate-Specific Membrane Antigen PET/Magnetic Resonance Imaging for the Planning of Salvage Radiotherapy in Patients with Prostate Cancer with Biochemical Recurrence After Radical Prostatectomy
(Journal article; Peer reviewed, 2019)Prostate-specific membrane antigen (PSMA) PET/magnetic resonance (MR) imaging can help distinguish between patients with prostate cancer with locoregional recurrence and those with distant metastases, even at low ... -
Protect us from ourselves: Balancing the parental instinct of saving
(Peer reviewed; Journal article, 2019)Background: Neonatologists, legal experts and ethicists extensively discuss the ethical challenges of decision-making when a child is born at the limit of viability. The voices of parents are less heard in this discussion. ... -
Protein tyrosine phosphatases in multiple myeloma
(Peer reviewed; Journal article, 2020)Many cell signaling pathways are activated or deactivated by protein tyrosine phosphorylation and dephosphorylation, catalyzed by protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs), respectively. Even ... -
Protein-protein interactions of the nuclear receprot NR4A2
(Master thesis, 2014)The Gastroenterology and Molecular cell biology research group examines biological mechanisms that are important in the development of gastric cancer. The peptide hormone gastrin is known to play a role in organization ...