Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 2013-2032 av 3427
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Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications
(Peer reviewed; Journal article, 2024)Background A considerable inter-individual variability has been reported in the relationship between methadone doses applied and serum concentrations achieved in methadone maintenance treatment. However, the underlying ... -
Methodology Matters: Comparing Approaches for Defining Persistent Symptoms after Mild Traumatic Brain Injury
(Peer reviewed; Journal article, 2021)Some people experience persistent post-concussion symptoms (PPCS) after mild traumatic brain injury (mTBI). A meaningful clinical classification and scientific progress are hampered by a lack of consensus regarding the ... -
Methods for specifying the target difference in a randomised controlled trial: the Difference ELicitation in TriAls (DELTA) systematic review
(Journal article; Peer reviewed, 2014)Background Randomised controlled trials (RCTs) are widely accepted as the preferred study design for evaluating healthcare interventions. When the sample size is determined, a (target) difference is typically specified ... -
Methplotlib: Analysis of modified nucleotides from nanopore sequencing
(Journal article; Peer reviewed, 2020)Summary Modified nucleotides play a crucial role in gene expression regulation. Here, we describe methplotlib, a tool developed for the visualization of modified nucleotides detected from Oxford Nanopore Technologies ... -
Metodeutvikling og validering av en kvantitativ UHPLC-MS/MS metode for analyse av tuberkulostatika i serum
(Master thesis, 2023)Tuberkulose er en infeksjonssykdom som krever omfattende behandling med flere typer antibiotika over lengre tid (minst seks måneder). Det er risiko for terapisvikt og toksiske effekter, og terapeutisk legemiddelmonitorering ... -
Metylfenidats kliniske farmakologi
(Master thesis, 2016)Bakgrunn: Attention-deficit/hyperactivity disorder/hyperkinetisk forstyrrelse (ADHD/HF) kjennetegnes av konsentrasjonsproblemer, hyperaktivitet og økt impulsivitet. 4,3 % og 1,7 % av henholdsvis gutter og jenter i aldersgruppen ... -
MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas
(Peer reviewed; Journal article, 2020)O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ... -
Microbial communities in seawater from an Arctic and a temperate Norwegian fjord and their potentials for biodegradation of chemically dispersed oil at low seawater temperatures
(Journal article; Peer reviewed, 2018)Biodegradation of chemically dispersed oil at low temperature (0–2 °C) was compared in natural seawater from Arctic (Svalbard) and a temperate (Norway) fjords. The oil was premixed with a dispersant (Corexit 9500) and ... -
Microbial community and metagenome dynamics during biodegradation of dispersed oil reveals potential key-players in cold Norwegian seawater
(Journal article; Peer reviewed, 2018)Oil biodegradation as a weathering process has been extensively investigated over the years, especially after the Deepwater Horizon blowout. In this study, we performed microcosm experiments at 5 °C with chemically dispersed ... -
Microbiota in inflammatory bowel disease
(Doctoral theses at NTNU;2021:86, Doctoral thesis, 2021) -
Microencapsulation of small intestinal neuroendocrine neoplasm cells for tumor model studies
(Journal article; Peer reviewed, 2012)Basic cancer research is dependent on reliable in vitro and in vivo tumor models. The serotonin (5‐HT) producing small intestinal neuroendocrine tumor cell line KRJ‐1 has been used in in vitro proliferation and secretion ... -
Microglia and macrophages in human glioblastomas: A morphological and immunohistochemical study
(Journal article; Peer reviewed, 2019)Glioblastomas (GBMs), a type of highly malignant brain tumour, contain various macrophages/microglia that are known as tumour‑associated macrophages (TAMs). These TAMs have various roles in tumour biology. Histopathological ... -
Microplastics; occurrence, levels and implications for environment and human health related to food. Scientific opinion of the Scientific Steering Committee of the Norwegian Scientific Committee for Food and Environment
(VKM Report;, Research report, 2019)The steering committee of VKM has self-initiated a mandate for an opinion on microplastics based on recently published international and/or national reports complemented with literature from December 2016 to February 2019. ... -
MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity
(Peer reviewed; Journal article, 2021)MicroRNAs (miRNAs) are small non-coding RNAs that have emerged as central regulators of gene expression and powerful biomarkers of disease. Much is yet unknown about their role in psoriasis pathology. To globally characterize ... -
MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood
(Journal article; Peer reviewed, 2012)Exploiting the properties of stem cells by microRNA (miRNA) profiling offers an attractive approach to identify new regulators of stem cell fate. Although numerous miRNA have been screened from hematopoietic stem cells ... -
MicroRNAs contribute to postnatal development of laminar differences and neuronal subtypes in the rat medial entorhinal cortex
(Journal article; Peer reviewed, 2017)The medial entorhinal cortex (MEC) is important in spatial navigation and memory formation and its layers have distinct neuronal subtypes, connectivity, spatial properties, and disease susceptibility. As little is known ... -
MicroRNAs in cell cycle regulation and DNA repair
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:94, Doctoral thesis, 2013) -
Microvascular proliferation in luminal A and basal-like breast cancer subtypes
(Journal article; Peer reviewed, 2015)Aims The aims of this study were to examine microvessel density (MVD), proliferating MVD (pMVD) and Vascular Proliferation Index (VPI) in basal-like phenotype (BP) and luminal A subtypes of breast cancer and to study their ... -
A middle-out modeling strategy to extend a colon cancer logical model improves drug synergy predictions in epithelial-derived cancer cell lines
(Peer reviewed; Journal article, 2020)Cancer is a heterogeneous and complex disease and one of the leading causes of death worldwide. The high tumor heterogeneity between individuals affected by the same cancer type is accompanied by distinct molecular and ... -
Mild to Moderate Cognitive Impairment Does Not Affect the Ability to Self-Report Important Symptoms in Patients With Cancer: A Prospective Longitudinal Multinational Study (EPCCS)
(Peer reviewed; Journal article, 2020)Context Patients with advanced cancer commonly suffer from both distressing symptoms and cognitive impairment, but the effect of cognitive impairment on the reliability and validity of symptom self-report is unknown. ...