Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1923-1942 av 3430
-
Macrophages as a modulator of PLA2G7 and DHRS9 in obesity in a depot dependent manner: implications in energy metabolism and inflammation
(Master thesis, 2022)Mange forskningsstudier har vist at makrofager i fettvev spiller en nøkkelrolle i fedme-indusert inflammasjon. Derfor har samspillet mellom metabolisme og immunsystem (immunometabolisme) blitt grundig undersøkt de siste ... -
Magnetic Resonance Imaging of Hypoxic-Ischemic Brain Injury Development in the Newborn Rat
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:125, Doctoral thesis, 2012) -
Maintenance pemetrexed therapy in advanced non-smallcell lung cancer
(Doctoral theses at NTNU;2023:312, Doctoral thesis, 2023)Lung cancer is the most common cancer world-wide, the third most common in Norway after colonand breast cancer, but the most common cause of cancer-related deaths both globally and nationally (1, 2). In 2021, 3499 new cases ... -
Major durable response of pembrolizumab in chemotherapy refractory small cell bladder cancer: A case report
(Peer reviewed; Journal article, 2020)Small cell carcinoma of the urinary bladder is a rare subtype (incidence of 1–9/1,000,000), characterized by an aggressive behavior with early metastasis and poor prognosis. Chemotherapy, radiation, and surgery are the ... -
Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication
(Peer reviewed; Journal article, 2020)The historically recent domestication of fishes has been essential to meet the protein demands ofa growing human population. Selection for traits of interest during domestication is a complexprocess whose epigenetic basis ... -
Malignant Mesothelioma: Virus, Biomarkers and Genes- a Translational Approach
(Doktoravhandlinger ved NTNU, 1503-8181; 2008:275, Doctoral thesis, 2008)Malignant mesothelioma is an asbestos-related, lethal treatment resistant tumour with increasing incidence worldwide. In four translational studies we have studied the pathogenesis of mesothelioma with regard to the SV40 ... -
Malignant Mesothelioma: Virus, Biomarkers and Genes- a Translational Approach
(Doktoravhandlinger ved NTNU, 1503-8181; 2008:275, Doctoral thesis, 2008)Malignant mesothelioma is an asbestos-related, lethal treatment resistant tumour with increasing incidence worldwide. In four translational studies we have studied the pathogenesis of mesothelioma with regard to the SV40 ... -
Malignant pleural mesothelioma: History, controversy and future of a manmade epidemic
(Journal article; Peer reviewed, 2015)Asbestos is the term for a family of naturally occurring minerals that have been used on a small scale since ancient times. Industrialisation demanded increased mining and refining in the 20th century, and in 1960, Wagner, ... -
Malnutrition, nutritional interventions and clinical outcomes of patients with acute small bowel obstruction: results from a national, multicentre, prospective audit
(Journal article; Peer reviewed, 2019)Objective The aim of this study was to assess the nutritional status of patients presenting with small bowel obstruction (SBO), along with associated nutritional interventions and clinical outcomes. Design Prospective ... -
The Mammalian Cap-Specific m<sup>6</sup>Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues
(Peer reviewed; Journal article, 2020)The 5′ end of eukaryotic mRNAs is protected by the m7G-cap structure. The transcription start site nucleotide is ribose methylated (Nm) in many eukaryotes, whereas an adenosine at this position is further methylated at the ... -
Management of a life-threatening intercostal artery bleeding, difficult to visualize in open surgery: a case report
(Peer reviewed; Journal article, 2020)Life-threatening bleeding from an intercostal artery is a rare and challenging event. A 74-year-old patient with a right-sided pleural effusion was treated by a pigtail pleural drain. He developed a large haemothorax, ... -
Manglende etterlevelse - også en bevisst handling
(Journal article; Peer reviewed, 2016)Alle pasienter har ulike oppfatninger av sykdom og legemidler. Pasienter veier gjerne nytten av legemiddelbehandlingen mot ulemp¬ene, og dette kommuniseres ikke alltid med helsepersonell. Tro på egen mestring av legemiddelregimet ... -
Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction: The HUNT2 Study in Norway
(Journal article; Peer reviewed, 2012)Objectives: Mannose-binding lectin (MBL) and ficolins activate the complement cascade, which is involved in atherogenesis. Based on a pilot study, we hypothesized that functional polymorphisms in the MBL gene (MBL2) ... -
The many functions of ESCRTs
(Peer reviewed; Journal article, 2019)Cellular membranes can form two principally different involutions, which either exclude or contain cytosol. The ‘classical’ budding reactions, such as those occurring during endocytosis or formation of exocytic vesicles, ... -
Mapping nanoparticles in hydrogels: A comparison of preparation methods for electron microscopy
(Journal article; Peer reviewed, 2018)The distribution of noble metal nanoparticles (NMNPs) in hydrogels influences their nanoplasmonic response and signals used for biosensor purposes. By controlling the particle distribution in NMNP-nanocomposite hydrogels, ... -
Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions
(Peer reviewed; Journal article, 2022)Environmental stressors such as repeated social defeat may initiate powerful activation of subconscious parts of the brain. Here, we examine the consequences of such stress (induced by resident-intruder paradigm) on the ... -
Mapping post - translational histone modifications and the TH2B variant in spermatogenesis
(Master thesis, 2012)Epigenetics has been defined by Goldberg et al. [1] as the study of heritable changes in gene expression or cellular phenotype which arises without changes in the DNA sequence. Post-translational histone modification and ... -
Mapping the human genetic architecture of COVID-19
(Journal article; Peer reviewed, 2021)The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ... -
Markers of autoimmunity in Latent Autoimmune Diabetes in Adults (LADA) and non-diabetic adults: Impact in phenotype and genetic predisposition: Results from the Nord-Trøndelag health study
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:113, Doctoral thesis, 2013)Diabetes is mainly classified: type 1 and type 2 diabetes. Type 1 diabetes is an autoimmune disease in which the body's immune system attacks and destroys the beta cells that produce insulin. Patients with type 2 diabetes ...