Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1744-1763 av 3426
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Investigating the causal effect of smoking on hay fever and asthma: A Mendelian randomization meta-analysis in the CARTA consortium
(Journal article; Peer reviewed, 2017)Observational studies on smoking and risk of hay fever and asthma have shown inconsistent results. However, observational studies may be biased by confounding and reverse causation. Mendelian randomization uses genetic ... -
Investigating the effect of sex and ketosis on weight-loss-induced changes in appetite
(Peer reviewed; Journal article, 2019)Background Diet-induced weight loss (WL) is usually accompanied by increased appetite, a response that seems to be absent when ketogenic diets are used. It remains unknown if sex modulates the appetite suppressant effect ... -
Investigating the immunomodulatory effects of SARS-CoV-2 proteins ORF3a, ORF6 and ORF9b on the inflammatory response of human lung epithelial cells
(Master thesis, 2022)The COVID-19 pandemic has taken an unprecedented number of lives and brought incredibly high social costs across the globe. The disease severity is associated with a strong innate immune dysregulation characterised by low ... -
Investigating the missing data mechanism in quality of life outcomes: a comparison of approaches
(Journal article; Peer reviewed, 2009)Background: Missing data is classified as missing completely at random (MCAR), missing at random (MAR) or missing not at random (MNAR). Knowing the mechanism is useful in identifying the most appropriate analysis. The ... -
Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium
(Journal article; Peer reviewed, 2014)Objectives: To investigate whether associations of smoking with depression and anxiety are likely to be causal, using a Mendelian randomisation approach. Design: Mendelian randomisation meta-analyses using a genetic ... -
Investigating the Role of PRL-3 and Targeting PHGDH in Multiple Myeloma
(Doctoral theses at NTNU;2020:378, Doctoral thesis, 2020)Myelomatose er en hematologisk kreftsykdom som skyldes klonal ekspansjon av plasmaceller som infiltrerer beinmargen. Til tross for fremskritt innen behandlingen av myelomatose, er sykdommen fortsatt uhelbredelig. Artiklene ... -
Investigation into the cardiovascular effects of the 2nd generation reverse transcriptase inhibitors Rilpivirine and Dapivirine
(Master thesis, 2021)Humant immunsviktvirus (HIV) er et virus som angriper immunsystemet og uten behandling fører til immunsviktsykdommen, ervervet immunsviktsyndrom (AIDS). Tidligere var behandlingen for denne gruppe pasienter dårlig, men ... -
Investigation of an outbreak caused by antibiotic susceptible Klebsiella oxytoca in a neonatal intensive care unit in Norway
(Journal article; Peer reviewed, 2018)Abstract Aim Klebsiella spp. have been stated to be the most frequent cause of neonatal intensive care unit (NICU) outbreaks. We report an outbreak of Klebsiella oxytoca in a NICU at a tertiary care hospital in Norway ... -
Investigation of Pattern Recognition Receptor Expression and Cytokine Responses in CAL-1 and PMDC05 cell lines and human Plasmacytoid Dendritic Cells (pDCs)
(Master thesis, 2022)Abstract will be available on 2027-06-30 -
Investigation of properties and classification of human transcription factors
(Doctoral theses at NTNU;2016:243, Doctoral thesis, 2016)Studier av egenskaper og klassifisering av humane transkripsjonsfaktorer Egenskaper og funksjonen av ulike celler bestemmes gjennom regulering av genuttrykket, og en rekke ulike mekanismer er aktive i den enkelte ... -
Investigation of single cells in tumor tissue and microRNAs in serum of colorectal cancer patients
(Master thesis, 2022)Kolorektal kreft er en sykdom som påvirker nesten 2 millioner mennesker hvert år, og omtrent 20% av pasientene blir diagnostisert ved avanserte kreftstadier hvor behandling har dårlig effekt, som følge av mangel på symptomer ... -
Investigation of the long-term sustainability of changes in appetite after weight loss
(Journal article; Peer reviewed, 2018)Background/Objective Diet-induced weight loss (WL) leads to a compensatory increase in appetite and changes in the plasma concentration of appetite-regulating hormones are likely to play a role. Whether these changes are ... -
Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice
(Journal article; Peer reviewed, 2016-05-04)Background: In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize, expressing the insecticidal Cry1Ab toxin, ... -
Involvement of NF-κB/IL-6 Pathway in the Processing of Colorectal Carcinogenesis in Colitis Mice
(Journal article; Peer reviewed, 2014)Nuclear factor-kappaB (NF-κB)/interleukin (IL-6) pathway links chronic inflammation to colitis associated cancer (CAC). In this study, we examined the dynamic temporal changes of the NF-κB/IL-6 pathway during the procession ... -
Involvement of the ASC-1 complex in processing of methylated DNA and RNA
(Doctoral theses at NTNU;2018:83, Doctoral thesis, 2018)Den grunnleggende informasjon om organismene ligger lagret i DNA, som er en polymer sammensatt av fire ulike nitrogenbaser bundet til en sukkerfosfat ryggrad. Langs DNA-tråden ligger ulike gener, og baserekkefølgen innen ... -
Iodine status and iodised salt consumption in portuguese school-aged children: The iogeneration study
(Journal article; Peer reviewed, 2017)The World Health Organization promotes salt iodisation to control iodine deficiency. In Portugal, the use of iodised salt in school canteens has been mandatory since 2013. The present study aimed to evaluate iodine status ... -
IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
(Journal article; Peer reviewed, 2015)Objectives: Biomarkers for diagnosis and therapy efficacy in tuberculosis (TB) are requested. We have studied biomarkers that may differentiate between active and latent TB infection (LTBI), the influence of HIV infection ... -
IQ, executive functions and brain findings in very low birth weight (VLBW) children and young adults
(Doctoral thesis at NTNU;2015:333, Doctoral thesis, 2015)IQ, eksekutive funksjoner og hjernefunn hos barn og unge voksne født prematurt med veldig lav fødselsvekt Medisinske fremskritt innen nyfødtmedisin har ført til økt overlevelsesrate av prematurt fødte barn de siste to ... -
Irisin reduces orthodontic tooth movement in rats by promoting the osteogenic potential in the periodontal ligament
(Peer reviewed; Journal article, 2023)Objectives Positive effects of irisin on osteogenic differentiation of periodontal ligament (PDL) cells have been identified previously, this study aims to examine its effect on orthodontic tooth movement (OTM) in ...