Viser treff 1107-1126 av 3433
-
Expanding the activity spectrum of antiviral agents
(Peer reviewed; Journal article, 2019) -
Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities
(Peer reviewed; Journal article, 2023)Gene regulation plays a critical role in the cellular processes that underlie human health and disease. The regulatory relationship between transcription factors (TFs), key regulators of gene expression, and their target ... -
Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma
(Journal article; Peer reviewed, 2018)Novel predictive tools for clear cell renal cell carcinoma (ccRCC) are urgently needed. MicroRNAs (miRNAs) have been increasingly investigated for their predictive value, and formalin-fixed paraffin-embedded biopsy archives ... -
Experiences among school personnel and school nurses on educational adaptations for students with CFS/ME: A qualitative interview study
(Peer reviewed; Journal article, 2021)Introduction: Chronic fatigue syndrome (CFS/ME) is a disabling disease severely impacting school attendance, education, and social life in young students. Uncertainties surrounding CFS/ME etiology may impact the interpretation ... -
Experiences and perceptions of foreign-language customers on medication information received in the pharmacy – a focus group study
(Peer reviewed; Journal article, 2021)Background In pharmacies, communication is essential for providing information about medicine and counselling customers on the correct use of medications. Previous studies have described pharmacists experiencing language ... -
Experiences of childbirth care among immigrant and non-immigrant women: a cross-sectional questionnaire study from a hospital in Norway
(Peer reviewed; Journal article, 2023)Background Immigrant women have higher risks for poor pregnancy outcomes and unsatisfactory birth experiences than the general population. The mechanisms behind these associations remain largely unknown, but they may ... -
Experimental-Computational Approaches to Identify Synergistic Effects of Anti-Cancer Drugs
(Doctoral theses at NTNU;2019:384, Doctoral thesis, 2019)Drug combinations are hoped to improve treatment response to anti-cancer drugs by targeting the cancers vulnerabilities at diverse trajectories. With a large number of approved agents of chemotherapeutic and targeted ... -
Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data.
(Journal article; Peer reviewed, 2019)Maximal expiratory airflow peaks early in the third decade of life, then gradually declines with age. The pattern of airflow through adulthood for individuals born very preterm (at <32 weeks’ gestation) or ... -
Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway
(Peer reviewed; Journal article, 2022)Previous studies indicate sex differences in incidence and severity of bloodstream infections (BSI). We examined the effect of sex on risk of BSI, BSI mortality, and BSI caused by the most common infecting bacteria. Using ... -
Explaining variation in cancer survival between 11 jurisdictions in the International Cancer Benchmarking Partnership: a primary care vignette survey
(Peer reviewed; Journal article, 2015)Objectives The International Cancer Benchmarking Partnership (ICBP) is a collaboration between 6 countries and 12 jurisdictions with similar primary care-led health services. This study investigates primary care physician ... -
Exploration of 27 plasma immune markers: A cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons
(Journal article; Peer reviewed, 2018)Background The prevalence of major depression (MD) according to population studies is the same for old (65 years and older) and younger adults. In contrast, an elevated proportion of old MD patients are hospitalized ... -
Exploring autophagy and its components in relation to the of the innate immune system
(Master thesis, 2009) -
Exploring Biomarkers for Weight Loss in Cancer Cachexia: The Prognostic Value of Serum sP-selectin, Activin A and Autophagy-stimulatory Activity
(Master thesis, 2012)Cancer cachexia is an extremely devastating wasting syndrome that adversely influences treatment response, quality of life and survival rates of patients. It involves severe metabolic imbalance resulting in progressive ... -
Exploring Dietary Intake in Adults with Severe Obesity and Associations with the FTO rs9939609 Genotypes
(Peer reviewed; Journal article, 2023)Background Few have studied the associations between rs9939609 genotypes in the obesity candidate locus FTO and energy and nutrient intakes and meal frequencies in adults with severe obesity. We are unaware of studies ... -
Exploring drug resistance mechanisms in Multiple Myeloma - Focusing on the role of immunoglobulin kappa light chain and protein secretion
(Master thesis, 2019)Multiple myeloma (MM) is a type of cancer arising in the bone marrow affecting the immunoglobulin (Ig) producing plasma cells. This causes an uncontrolled proliferation of a single plasma cell clone and an overproduction ... -
Exploring lifestyle and risk in preventing type 2 diabetes-a nested qualitative study of older participants in a lifestyle intervention program (VEND-RISK)
(Journal article; Peer reviewed, 2016)Background: Lifestyle intervention may reduce the development of type 2 diabetes among high-risk individuals. The aim of this study was to explore how older adults perceived their own lifestyle and being at increased ... -
Exploring responses of type I and type III interferons in human macrophages
(Master thesis, 2021)Interferons are antiviral cytokines induced during viral infection. Type I and III IFNs are thought to share some of the same transcriptional outputs, yet some biological responses are distinct. IFN-λ receptor (IFNLR1) ... -
Exploring the Crosstalk Between RIG-I-mediated Signalling and β-catenin
(Master thesis, 2011)Hepatocellular carcinoma (HCC) is the most common type of liver cancer and among the leading causes of cancer related death worldwide. Hepatocarcinogenesis has been attributed to chronic viral infection and alterations in ... -
Exploring the diagnostic potential of adding T2 dependence in diffusion-weighted MR imaging of the prostate
(Peer reviewed; Journal article, 2021)Background: Magnetic resonance imaging (MRI) is essential in the detection and staging of prostate cancer. However, improved tools to distinguish between low-risk and high-risk cancer are needed in order to select the ... -
Exploring the fungal microbiome in breast cancer patients
(Master thesis, 2021)The role of the Fungal Microbiome in the human body has been gradually revealed. Its presence in the gut, although scarce in comparison to bacteria, is now associated with several physiologic functions such as immune ...