Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 371-390 of 3524
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Brain Volumes and Abnormalities in Adults Born Preterm at Very Low Birth Weight
(Journal article; Peer reviewed, 2022) -
Brain volumes and cognitive function in very-low-birth-weight (VLBW) young adults
(Journal article; Peer reviewed, 2014)Background Preterm born very-low-birth-weight (VLBW: birth weight ≤1500 g) survivors have increased risk of perinatal brain injury that may cause deviant brain development and later neuroimpairments, including reduced ... -
BRD4 degradation by PROTAC technology in carfilzomib-treated multiple myeloma cells
(Master thesis, 2020) -
Breaking the ‘conspiracy of silence’: How to address sexual dysfunction in a gynecological/ obstetric out-patient setting
(Master thesis, 2016)Background: This study set out to examine if, and to what extent, women would like gynecologists to ask about sexual function during a standard out-patient interview. A secondary aim was to find out if women would like ... -
Breakthrough and Episodic Cancer Pain from a Palliative Care Perspective
(Peer reviewed; Journal article, 2023)Cancer pain intensity (PI) fluctuates, but the relationship between pain flares and background pain with respect to pain management is not settled. We studied how flare and background PIs corresponded with treatment results ... -
Breakthrough cancer pain in 2020
(Peer reviewed; Journal article, 2020)Purpose of review An overview on breakthrough cancer pain (BTCP), including inherent limitations of the terminology, assessment, clinical presentation, and treatment options. Recent findings The estimated prevalence ... -
Breast Cancer Patients’ Experiences with Information and Communication in Cancer Disease Trajectories
(Journal article; Peer reviewed, 2017)Patients’ experiences have been used as an indicator for hospital quality for a long time. The concept of patient experiences has many facets. One aspect of particular importance for optimal treatment and patients’ quality ... -
Breeze 2.0: An interactive web-tool for visual analysis and comparison of drug response data
(Peer reviewed; Journal article, 2023)Functional precision medicine (fPM) offers an exciting, simplified approach to finding the right applications for existing molecules and enhancing therapeutic potential. Integrative and robust tools ensuring high accuracy ... -
Brief Report: The Genetic Profile of Rheumatoid Factor?Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis
(Journal article; Peer reviewed, 2018) -
Broad-Spectrum Antibacterial Peptide Kills Extracellular and Intracellular Bacteria Without Affecting Epithelialization
(Peer reviewed; Journal article, 2021)New antibacterial drugs with novel modes of action are urgently needed as antibiotic resistance in bacteria is increasing and spreading throughout the world. In this study, we aimed to explore the possibility of using ... -
Broad-Spectrum Antiviral monotherapies: in silico drug repositioning against emergent viruses
(Master thesis, 2022)Utbruddet av SARS-CoV-2 har demonstrert realiteten av globale virale trusler. SARS-CoV-2 krysset arts barrierer og forårsaket en pandemi som verden ikke var forberedt på. Antiviraler er medikamenter som hemmer formeringen ... -
Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in nonhuman primates
(Peer reviewed; Journal article, 2023)The COVID-19 pandemic represents a global challenge that has impacted and is expected to continue to impact the lives and health of people across the world for the foreseeable future. The rollout of vaccines has provided ... -
Bronchial microdialysis monitoring of inflammatory response in open abdominal aortic aneurysm repair; an observational study.
(Journal article; Peer reviewed, 2017)Aortic surgery results in ischemia–reperfusion injury that induces an inflammatory response and frequent complications. The magnitude of the inflammatory response in blood and bronchi may be associated with the risk of ... -
Bronchoalveolar lavage fluid IFN- γ + Th17 cells and regulatory T cells in pulmonary sarcoidosis
(Journal article; Peer reviewed, 2014)In sarcoidosis, increased Th17 cell fractions have been reported in bronchoalveolar lavage fluid, and elevated numbers of Th17 cells producing IFN-𝛾 have been observed in peripheral blood. The balance between Th1, Th17, ... -
Bruk av botulinumtoksin A til barn med cerebral parese
(Peer reviewed; Journal article, 2019)BAKGRUNN Intramuskulære injeksjoner med botulinumtoksin A har i over 20 år vært en etablert behandling av spastisitet hos barn med cerebral parese. Vi undersøkte hvor mange barn med cerebral parese i Norge som får slik ... -
Bruk av gentamicin som oppstartsantibiotikum ved St. Olavs hospital HF - en prospektiv observasjonsstudie
(Master thesis, 2024)Hensikt: Antibiotisk terapi med aminoglykosidet gentamicin i kombinasjon med enkelte betalaktam-antibiotika er anbefalt som standard empirisk oppstartsbehandling ved en rekke infeksjoner, spesielt alvorlige infeksjoner, i ... -
Bruk av piperacillin/tazobaktam ved behandling av infeksjoner i abdomen - Kan intervensjoner bidra til å optimalisere forskrivningen?
(Master thesis, 2022)Introduksjon: Antibiotikaresistens er en trussel mot folkehelsen. Effektive tiltak for å bremse utviklingen er viktig for å kunne ha effektiv antibiotikabehandling også i fremtiden. De nasjonale retningslinjene for ... -
Bruk av psykofarmaka der farmakogenetiske analyser er aktuelt
(Master thesis, 2022)Bakgrunn: En betydelig andel av den norske befolkningen vil rammes av psykiske lidelser i løpet av ett år, og mange vil ha behov for medikamentell behandling med psykofarmaka. Det er imidlertid flere utfordringer knyttet ... -
Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study
(Journal article; Peer reviewed, 2017)Background Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods We studied the burden of disease and death related to BSI in ... -
The burden of hospital-attended influenza in Norwegian children
(Journal article; Peer reviewed, 2022)