Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1996-2015 av 3502
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Markers of placental insufficiency: etiology and the risk of cerebral palsy:Population based studies of preeclampsia, low birth weight, and abnormal placental weight
(Doctoral thesis at NTNU;2015:172, Doctoral thesis, 2015)Placental insufficiency may be defined as a placenta not able to perform its central tasks; namely, delivery of sufficient oxygen and nutrients to the developing fetus. In this thesis, preeclampsia, fetal growth restriction ... -
Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report
(Peer reviewed; Journal article, 2021)Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ... -
Massive parallel amplicon sequencing of the mismatch repair genes MSH2, MSH6, MLH1 and PMS2. Implementation of hereditary and non-hereditary subtypes of colorectal cancer
(Master thesis, 2013) Colorectal cancer is the one of the most frequent malignancies and accounts for approximately 3500 new cases each year in Norway. Colorectal cancer is a heterogeneous disorder and can be divided into three main groups: ... -
Maternal alcohol and drug use during pregnancy affects the motor behaviour and general movements of infants aged 3–4 months
(Peer reviewed; Journal article, 2020)Background Exposure of alcohol and/or other addictive drugs in pregnancy is a documented risk factor for later neurological impairment. Aims The aim of the study was to determine whether infants suffering from prenatal ... -
Maternal exposure to childhood maltreatment and mental and behavioral disorders in children
(Peer reviewed; Journal article, 2022)Exposure to maltreatment in childhood is associated with lifelong risk of mental and behavioral disorders. Whether the effects extend to the next generation remains unclear. We examined whether maternal exposure to childhood ... -
Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium
(Peer reviewed; Journal article, 2021)Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ... -
Maternal mental health and adverse birth outcomes
(Peer reviewed; Journal article, 2022)Recent research in economics emphasizes the role of in utero conditions for the health endowment at birth and in early childhood and for social as well as economic outcomes in later life. This paper analyzes the relation ... -
Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study
(Peer reviewed; Journal article, 2021)Objective Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with potential effects on offspring both genetically and through altered intrauterine environment. Metformin, which ameliorate hormonal disturbances ... -
Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring
(Peer reviewed; Journal article, 2020)Background/Objectives Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal ... -
Maternal serum levels of prokineticin-1 related to pregnancy complications and metformin use in women with polycystic ovary syndrome: a post hoc analysis of two prospective, randomised, placebo-controlled trials
(Peer reviewed; Journal article, 2023)Objective Serum prokineticin-1 (s-PROK1) in the second and third trimester of pregnancy is positively correlated to preeclampsia, intrauterine growth restriction (IUGR) and preterm delivery. Women with polycystic ovary ... -
Maternal serum retinol, 25(OH)D and 1,25(OH)2D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up
(Journal article; Peer reviewed, 2019)Background Vitamin A and D deficiency is prevalent in pregnant women worldwide. Both vitamins are involved in fetal skeletal development. A positive association between maternal vitamin D levels and offspring bone mineral ... -
Maternal vitamin D status in pregnancy and molar incisor hypomineralisation and hypomineralised second primary molars in the offspring at 7–9 years of age: a longitudinal study
(Peer reviewed; Journal article, 2022)Purpose The study aimed to investigate associations between maternal vitamin D status during pregnancy and molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM) among children. Methods The ... -
Matrix Metalloproteinase (MMP)-17 Regulates Intestinal Regeneration after Irradiation
(Master thesis, 2019)The intestinal epithelium is a multitasking tissue and has a large flexibility to adapt to different types of insults. This is mostly due to the proliferative intestinal stem cells (ISCs) at the bottom of the intestinal ... -
Maximal strength training-induced increase in efferent neural drive is not reflected in relative protein expression of SERCA
(Peer reviewed; Journal article, 2021)Introduction Maximal strength training (MST), performed with heavy loads (~ 90% of one repetition maximum; 1RM) and few repetitions, yields large improvements in efferent neural drive, skeletal muscle force production, and ... -
Måling av overhydrering, fett- og muskelmasse hos predialytiske pasienter med kronisk nyresykdom med bruk av bioimpedance spektroskopi
(Master thesis, 2015)Innledning: Overhydrering er en vanlig følge av kronisk nyresykdom (KNS) og er assosiert med utvikling av kardiovaskulær sykdom. Måling av vannmengde, samt fett-og muskelmasse er derfor viktig hos pasienter med KNS. ... -
Mcl-1 and Bcl-xL levels predict responsiveness to dual MEK/Bcl-2 inhibition in B-cell malignancies
(Peer reviewed; Journal article, 2021)Most patients with chronic lymphocytic leukemia (CLL) initially respond to targeted therapies, but eventually relapse and develop resistance. Novel treatment strategies are therefore needed to improve patient outcomes. ... -
MDM2 is a useful prognostic biomarker for resectable gastric cancer
(Journal article; Peer reviewed, 2013)Expression of MDM2 protein appears to be increased in malignancy and correlated to prognosis of tumors, but its role in gastric cancer remains controversial. Our recent investigations indicated that JWA was a novel candidate ... -
Measurement of ciliary beating and fluid flow in the zebrafish adult telencephalon
(Peer reviewed; Journal article, 2022)Motile cilia are hair-like structures that move and propel fluid, playing important roles in the physiology of organs. Here, we present a protocol to visualize and measure ciliary beating and cerebrospinal fluid (CSF) flow ... -
Measurement of health-related quality of life during chemotherapy -the importance of timing
(Journal article; Peer reviewed, 2017)Background: Side effects of chemotherapy may occur at different time-points in the treatment cycle, and the exact assessment time relative to chemotherapy may affect HRQoL scores. The current study examined the variation ... -
Measures of co-expression for improved function prediction of long non-coding RNAs
(Journal article; Peer reviewed, 2018)Background Almost 16,000 human long non-coding RNA (lncRNA) genes have been identified in the GENCODE project. However, the function of most of them remains to be discovered. The function of lncRNAs and other novel genes ...