Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1127-1146 av 3588
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Evolution and risk factors of anal incontinence during the first 6 years after first delivery: a prospective cohort study
(Journal article; Peer reviewed, 2020) -
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
(Journal article; Peer reviewed, 2017)Background: Robust biomarkers that identify prostate cancer patients with high risk of recurrence will improve personalised cancer care. In this study, we investigated whether tissue metabolites detectable by high-resolution ... -
Examination of different APIM-variants and APIM's role in TRF2 protection of the telomere ends
(Master thesis, 2013)Most chemotherapeutic drugs induce DNA damage to the cells. However, the toxicity of DNA damaging drugs can be reduced by DNA repair mechanisms, and the cancer cells can survive despite the damage. Therefore, by targeting ... -
Examinations of the functionality of APIM in TRF2 and the importance for telomere stability
(Master thesis, 2014)Maintaining genome integrity is crucial for life, and therefore, complex control and repair mechanisms have evolved. Because cells are especially susceptible to damage during replication, many DNA repair pathways are coupled ... -
Examining differences in placental efficiency following exposure to antidepressants and current depression: Findings from an Australian pregnancy cohort study
(Peer reviewed; Journal article, 2022)Introduction Placental dysfunction and inefficiency, is important in understanding fetal growth restriction and low birth weight. Two recent studies have examined the relationship between antidepressant use in pregnancy ... -
Examining the educational impact of the mini-CEX: a randomised controlled study
(Journal article; Peer reviewed, 2021)Background: The purpose of this study is to evaluate the mini-Clinical Evaluation Exercise (mini-CEX) as a formative assessment tool among undergraduate medical students, in terms of student perceptions, effects on direct ... -
Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway
(Journal article; Peer reviewed, 2016)The goal of biomarker research is to identify clinically valid markers. Despite decades of research there has been disappointingly few molecules or techniques that are in use today. The “1st International NTNU Symposium ... -
Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins
(Journal article; Peer reviewed, 2018)Cytosine (C) in DNA is often modified to 5-methylcytosine (m5C) to execute important cellular functions. Despite the significance of m5C for epigenetic regulation in mammals, damage to m5C has received little attention. ... -
Executive Functions in the Chronic Phase of Pediatric Acquired Brain Injury: A randomized controlled trial investigating the efficacy of pediatric Goal Management Training and Associations with Long-term Outcome
(Doctoral theses at NTNU;2024:304, Doctoral thesis, 2024)Pediatric acquired brain injury (pABI), both traumatic and non-traumatic such as brain tumor or stroke, result in more diffuse and enduring impairments compared to adult ABI. These injuries, occurring during ongoing ... -
Exercise and nutrition interventions in patients with head and neck cancer during curative treatment: A systematic review and meta-analysis
(Peer reviewed; Journal article, 2020)The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck ... -
Exercise During Pregnancy
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:144, Doctoral thesis, 2012)Friske gravide anbefales å trene regelmessig under svangerskapet for å fortsette å oppnå de samme helsegevinstene som ved trening i ikke-gravid tilstand. Når det gjelder forebygging og behandling av svangerskapsrelaterte ... -
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
(Journal article; Peer reviewed, 2017)Physical exercise can improve brain function and delay neurodegeneration; however, the initial signal from muscle to brain is unknown. Here we show that the lactate receptor (HCAR1) is highly enriched in pial fibroblast-like ... -
Exercise prior to assisted fertilization in overweight and obese women (FertilEx): study protocol for a randomized controlled trial
(Journal article; Peer reviewed, 2016)Background Overweight and obese women show reduced conception rates compared to women of normal weight. Insulin resistance and increased amount of visceral fat may be important mechanisms for reduced fertility in these ... -
Exercise Self-Efficacy and patient global assessment were associated with 6-min walk test distance in persons with rheumatoid arthritis
(Peer reviewed; Journal article, 2022)Introduction: Low functional capacity is related to future loss of daily function and cardiovascular events. The present study explored the associations of patient-reported outcome measures (PROMs) and disease-specific ... -
Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction
(Journal article; Peer reviewed, 2021)Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ... -
Exercise training and high-sensitivity cardiac troponin-I in patients with heart failure with reduced ejection fraction
(Journal article; Peer reviewed, 2024)Aims: The aims of this sub-study of the SMARTEX trial were (1) to evaluate the effects of a 12-week exercise training programme on serum levels of high sensitivity cardiac troponin I (hs-cTnI) in patients with moderate ... -
Exercise training during pregnancy reduces circulating insulin levels in overweight/obese women postpartum: secondary analysis of a randomised controlled trial (the ETIP trial)
(Journal article; Peer reviewed, 2018)Background The primary aim was to investigate if supervised exercise training during pregnancy could reduce postpartum weight retention (PPWR) three months after delivery in overweight and obese women. We also measured ... -
Exercise Training in Pregnancy for obese women (ETIP): study protocol for a randomised controlled trial
(Journal article; Peer reviewed, 2011)Both maternal pre-pregnancy obesity and excessive gestational weight gain are increasing in prevalence and associated with a number of adverse pregnancy outcomes for both mother and child. Observational studies regarding ... -
Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN
(Peer reviewed; Journal article, 2020)Objective We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. Methods We used multiple in vivo and in vitro methods to explore the mechanisms ... -
Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain
(Peer reviewed; Journal article, 2023)Background Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer's disease (AD). These beneficial effects may be partly mediated by blood-borne factors. ...