Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 393-412 of 1899
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Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: Clinical results from a randomised phase-2 study (NordCML006)
(Journal article, 2015)We randomised 46 newly diagnosed patients with chronic myeloid leukaemia (median age 56) to receive dasatinib 100 mg QD or imatinib 400 mg QD and report outcome as an intention-to-treat analysis with 36 months follow-up. ... -
Decrease in use of manual vacuum aspiration in postabortion care in Malawi: A cross-sectional study from three public hospitals, 2008-2012
(Journal article; Peer reviewed, 2014)Objectives: To investigate the use of manual vacuum aspiration in postabortion care in Malawi between 2008–2012. Methods: A retrospective cross-sectional study was done at the referral hospital Queen Elisabeth Central ... -
Decreasing prevalence and severity of cerebral palsy in Norway among children born 1999 to 2010 concomitant with improvements in perinatal health
(Journal article; Peer reviewed, 2018)Background The aim of our study was to explore if the prevalence and clinical characteristics of cerebral palsy (CP), concomitant with perinatal health indicators in the general population, remained unchanged for children ... -
Deep-inspiration breath-hold - Development and utilization of a deep-inspiration breath-hold system for breast cancer radiotherapy
(Doctoral theses at NTNU;2018:315, Doctoral thesis, 2018)The purpose of this thesis was to develop a deep-inspiration breath-hold (DIBH) system and study the performance and clinical implications in the treatment of leftsided breast cancer and radiotherapy. This was investigated ... -
Degradation and mobility of pesticides in Norwegian soils. Opinion of the Panel on Plant Protection Products of the Norwegian Scientific Committee for Food Safety
(VKM Report;, Research report, 2015)In this report the following topic of pesticides and fate in Norway has been outlined covering: 1. Factors influencing degradation of pesticides. 2. Description and update of datasets on soil and climate in agricultural ... -
Delivery room routines and initial assessment and treatment for infants born at 32 to 35 weeks of gestation.: A multicentre pilot study comparing three different hospitals
(Master thesis, 2011)Objective: To compare routines and results regarding immediate postnatal treatment of preterm infants between three hospitals prior to the introduction of Kangaroo Care in the delivery room in order to ensure comparable ... -
Deltageres erfaringer med informasjonen om legemiddelbruk på pasientopplæringskurs ved to norske sykehus – en kvalitativ studie
(Master thesis, 2019)Sammendrag: Bakgrunn: Pårørende- og pasientopplæring er en av sykehusenes fire arbeidsoppgaver og tilbys ved sykehus over hele landet. Dette er et tilbud for mennesker med langvarige sykdommer eller kroniske lidelser. ... -
Dental calculus stimulates interleukin-1β secretion by activating NLRP3 inflammasome in human and mouse phagocytes
(Journal article; Peer reviewed, 2016)Dental calculus is a mineralized deposit associated with periodontitis. The bacterial components contained in dental calculus can be recognized by host immune sensors, such as Toll-like receptors (TLRs), and induce ... -
Depletion of the human N-terminal acetyltransferase hNaa30 disrupts Golgi integrity and ARFRP1 localization
(Journal article; Peer reviewed, 2017)The organization of the Golgi apparatus (GA) is tightly regulated. Golgi stack scattering is observed in cellular processes such as apoptosis and mitosis, and has also been associated with disruption of cellular lipid ... -
Depression and Depressive Symptoms in Advanced Cancer Patients - Assessment, Classification and Treatment
(Doctoral thesis at NTNU;2015:199, Doctoral thesis, 2015)Summary in Norwegian: Depresjon og symptomer på depresjon – kartlegging, klassifisering og behandling Depresjon og depressive symptomer er en belastning for pasienter med langtkommen kreft. Anslag som er gjort av ... -
Depression in palliative care cancer patients - Assessment and classification
(Doctoral theses at NTNU;2018:12, Doctoral thesis, 2018)Palliative care aims at improving quality of life and reducing suffering in patients with lifethreatening illness through the early identification, assessment and treatment of problems. Depression reduces quality of life ... -
Depression-A Major Contributor to Poor Quality of Life in Patients With Advanced Cancer
(Journal article, 2017)Context Quality of life (QoL) and depression are important patient-reported outcomes in cancer care. However, the relative importance of depression severity in predicting QoL remains unclear because of few methodologically ... -
Detailed flow visualization in fetal and neonatal hearts using 2-D speckle tracking
(Journal article, 2016)Two-dimensional blood speckle tracking has shown promise for measuring the complex flow patterns in neonatal hearts when based on linear array and high-frame-rate plane wave imaging. For phased array pediatric imaging, ... -
Detailed statistical analysis plan for the Danish Palliative care trial (DanPaCT)
(Journal article; Peer reviewed, 2014)Background Advanced cancer patients experience considerable symptoms, problems, and needs. Early referral of these patients to specialized palliative care (SPC) could offer improvements. The Danish Palliative Care Trial ... -
Detecting Toll-Like Receptor 8
(Master thesis, 2020)Toll-lignende reseptorer (TLR)er er reseptorer i det iboende immunsystemet som kan binde et bredt utvalg av mikrobe-tilknyttede molekylære mønstre (MAMP)s. Ved deres aktivering, utløses et bredt spekter av cellulære ... -
Detection and differentiation of breast cancer sub-types using a cPLA2a activatable fluorophore
(Journal article; Peer reviewed, 2019)Cytosolic phospholipase A2α (cPLA2α) has been shown to be elevated in breast cancer and is a potential biomarker in the differentiation of molecular sub-types. Using a cPLA2α activatable fluorophore, DDAO arachidonate, we ... -
Detection of congenital heart defects in a non-selected population of 42,381 fetuses
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:112, Doctoral thesis, 2006)Bakgrunn Siden 1986 har alle gravide i Norge fått tilbud om en ultralydundersøkelse ved 18 uker i svangerskapet. En av hensiktene med undersøkelsen er å oppdage sykdom hos fosteret for å optimalisere oppfølging, tidspunkt ... -
Detection of spliced mRNA from human bocavirus 1 in clinical samples from children with respiratory tract infections
(Journal article; Peer reviewed, 2013)Human bocavirus 1 (HBoV1) is a parvovirus associated with respiratory tract infections (RTIs) in children, but a causal relation has not yet been confirmed. To develop a qualitative reverse transcription PCR to detect ... -
Deterioration in Muscle Mass and Physical Function Differs According to Weight loss History in Cancer Cachexia
(Journal article; Peer reviewed, 2019)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ...