Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 993-1012 av 3585
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Effects of cPLA2a inhibition in the MDA-MB-468 cell model system for basal-like breast cancer and/or triple negative breast cancer
(Master thesis, 2016)Basal-like breast cancer (BLBC) is a highly aggressive breast cancer sub-type and represents ~15% of all breast cancers. BLBC are often associated with early age of onset, early relapse and poor overall survival in contrast ... -
Effects of cPLA2α inhibition in the MDAMB-468 cell model system for basal-like breast cancer and/or triple negative breast cancer
(Master thesis, 2016)Basal-like breast cancer (BLBC) is a highly aggressive breast cancer sub-type and represents ~15% of all breast cancers. BLBC are often associated with early age of onset, early relapse and poor overall survival in contrast ... -
Effects of current parenteral nutrition treatment on health-related quality of life, physical function, nutritional status, survival and adverse events exclusively in patients with advanced cancer: A systematic literature review
(Journal article; Peer reviewed, 2019)Background: The aim was to evaluate the effects of current parenteral nutrition (PN) treatment on clinical outcomes in patients with advanced cancer. Methods: This review was conducted according to the PRISMA guidelines ... -
Effects of Deucravacitinib in Intestinal Epithelial Cells
(Master thesis, 2024)Bakgrunn: Inflammatorisk tarmsykdom (IBD), inkludert Crohns sykdom og ulcerøs kolitt, referer til en gruppe kroniske medisinske lidelser som forårsaker vedvarende betennelse i mage-tarmkanalen. Den eksakte årsaken til IBD ... -
Effects of doxorubicin on cell death and the transcriptome in human AC16 cardiomyocytes
(Master thesis, 2022)Bakgrunn: Kreft og hjarte- og karsjukdom er leiande dødsårsaker i verda. Doxorubicin er mykje nytta som cellegift i kreftbehandling, men utvikling av kardiotoksisitet avgrensar bruken. Faktorar som bidreg til doxorubicin-indusert ... -
Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats
(Journal article; Peer reviewed, 2014)Background: A combined procedure of sleeve gastrectomy and duodenal switch (SG+DS) has been applied to the treatment of super obesity. The aim of the present study was to test whether duodenal switch alone (DS) leads to ... -
Effects of exercise intensity and nutrition advice on myocardial function in obese children and adolescents: a multicentre randomised controlled trial study protocol.
(Journal article; Peer reviewed, 2016)Introduction The prevalence of paediatric obesity is increasing, and with it, lifestyle-related diseases in children and adolescents. High-intensity interval training (HIIT) has recently been explored as an alternate to ... -
Effects of FKBP12-degrading PROTACs on receptor-specific TGF-β signaling in multiple myeloma
(Master thesis, 2021)Abstract Background and aims: Multiple myeloma (MM) is a form of cancer caused by the proliferation of aberrant plasma cells. Myeloma cells are addicted to the MYC oncogene, and this research group has previously shown ... -
Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
(Journal article; Peer reviewed, 2019)To address the shortcomings associated with corneal transplants, substantial efforts have been focused on developing new modalities such as xenotransplantion. Xenogeneic corneas are anatomically and biomechanically similar ... -
Effects of hexyl aminolevulinate and Amphinex based photodynamic therapy and photochemical internalization - in vitro studies using rat bladder cancer cells
(Master thesis, 2011)Photodynamic therapy (PDT) is a treatment modality which involves application of photosensitizers and their ability to accumulate selectively and damage cancer cells in presence of light. Light induced damage to cancer ... -
Effects of High Intensity Interval Training and Strenght Training on Metabolic, Cardiovascular and Hormonal Outcomes in Women with Polycystic Ovary Syndrome: A Pilot Study
(Journal article; Peer reviewed, 2015)Background: Polycystic ovary syndrome is a common endocrinopathy in reproductive-age women, and associates with insulin resistance. Exercise is advocated in this disorder, but little knowledge exists on the optimal ... -
Effects of hypoxia/reoxygenation and miR-24-3p in human cardiomyocyte models
(Master thesis, 2020)Background: Effective cardioprotective therapies targeting the reperfusion phase of ischemia/reperfusion (I/R) injury are lacking, which remain one of the top unmet clinical needs in cardiology. MicroRNAs (miRNAs) are a ... -
Effects of JAK inhibitor Brepocitinib on Intestinal Epithelial Cells
(Master thesis, 2024)Bakgrunn og mål: Inflammatorisk tarmsykdom (IBD) inkluderer en gruppe kroniske inflammatoriske lidelser som påvirker fordøyelseskanalen. Tarmepitelceller spiller en viktig rolle i opprettholdelsen av homeostasen i tarmen ... -
Effects of lost microRNA regulation at the global and single gene level in mammalian cells
(Doctoral thesis at NTNU;2014:307, Doctoral thesis, 2014) -
Effects of overexpressing NOR-1 on cell death and cell viability in human cardiomyocytes during doxorubicin-induced stress
(Master thesis, 2021)Koronar hjertesykdom er den ledende dødsårsaken i verden, karakterisert av redusert blodforsyning til hjertet. Ubehandlet kan dette føre til en fullstendig blokkering av koronararteriene, kjent som et hjerteinfarkt. ... -
Effects of photodynamic therapy by TPCS2a on glioma cell lines - in vitro and in vivo studies
(Master thesis, 2021)Ondartet glioma er en alvorlig sykdom som ofte er forbundet med en dårlig prognose. Fotodynamisk terapi (PDT) og fotokjemisk internalisering (PCI) er lovende terapeutiske prinsipper for økende eekt av gliomabehandling, ... -
Effects of Photodynamic Therapy on Protein Expressionin Rat Bladder Cancer Cells
(Master thesis, 2010)Photodynamic therapy (PDT) is an effective treatment involving light and a photosensitizer used in conjunction with molecular oxygen to elicit cell death. The purpose of this study is search for changes in protein expression ... -
Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants
(Journal article; Peer reviewed, 2018)Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely ... -
Effects of Purple Coneflower (Echinacea purpurea) on CYP3A4 Metabolism and P-glycoprotein Mediated Transport in Vitro
(Doctoral Theses at NTNU, 1503-8181; 2012:365, Doctoral thesis, 2012)Solhatt har blitt et av de vanligste urtepreparatene på verdensmarkedet, og markedsføres for sin effekt mot luftveisinfeksjoner og forkjølelse. Sambruk av naturpreparater og legemidler forekommer ofte, og det er kjent at ... -
Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies
(Peer reviewed; Journal article, 2022)Background Existing evidence on the effects of race and ethnicity on pregnancy outcomes is restricted to individual studies done within specific countries and health systems. We aimed to assess the impact of race and ...