Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 953-972 av 3426
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Effects of antenatal diet and physical activity on maternal and fetal outcomes: Individual patient data meta-analysis and health economic evaluation
(Journal article; Peer reviewed; Research report, 2017)Abstract Background Diet- and physical activity-based interventions in pregnancy have the potential to alter maternal and child outcomes. Objectives To assess whether or not the effects of diet and lifestyle ... -
Effects of APIM-containing peptides on the regulation of the PI3K/Akt and MEK/ERK pathways
(Master thesis, 2013)PI3K/Akt and MEK/ERK pathways are important cellular signaling system which controls many vital cellular processes, including cell survival, proliferation, differentiation and migration. These pathways are often deregulated ... -
Effects of bone morphogenetic proteins, hepatocyte growthfactor and interleukin-21 in multiple myeloma
(Doktoravhandlinger ved NTNU, 1503-8181; 2006:4, Doctoral thesis, 2006)The studies presented in this thesis answer some questions, but also raise new questions which should be explored in future studies. The bone marrow microenvironment is a complex system, and is difficult to study in vitro. ... -
Effects of Budesonide on the Intestinal Epithelium: Studies using IBD patient-derived Colonoids
(Master thesis, 2021)Bakgrunn: Tarmepitelcellene er etter hvert anerkjent som en viktig faktor i sykdomsbildet til inflammatoriske tarmsykdom (IBD). Det tradisjonelle anti-inflammatoriske steroid- legemiddelet budesonid er mye brukt i behandling ... -
Effects of cPLA2a inhibition in the MDA-MB-468 cell model system for basal-like breast cancer and/or triple negative breast cancer
(Master thesis, 2016)Basal-like breast cancer (BLBC) is a highly aggressive breast cancer sub-type and represents ~15% of all breast cancers. BLBC are often associated with early age of onset, early relapse and poor overall survival in contrast ... -
Effects of cPLA2α inhibition in the MDAMB-468 cell model system for basal-like breast cancer and/or triple negative breast cancer
(Master thesis, 2016)Basal-like breast cancer (BLBC) is a highly aggressive breast cancer sub-type and represents ~15% of all breast cancers. BLBC are often associated with early age of onset, early relapse and poor overall survival in contrast ... -
Effects of current parenteral nutrition treatment on health-related quality of life, physical function, nutritional status, survival and adverse events exclusively in patients with advanced cancer: A systematic literature review
(Journal article; Peer reviewed, 2019)Background: The aim was to evaluate the effects of current parenteral nutrition (PN) treatment on clinical outcomes in patients with advanced cancer. Methods: This review was conducted according to the PRISMA guidelines ... -
Effects of doxorubicin on cell death and the transcriptome in human AC16 cardiomyocytes
(Master thesis, 2022)Bakgrunn: Kreft og hjarte- og karsjukdom er leiande dødsårsaker i verda. Doxorubicin er mykje nytta som cellegift i kreftbehandling, men utvikling av kardiotoksisitet avgrensar bruken. Faktorar som bidreg til doxorubicin-indusert ... -
Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats
(Journal article; Peer reviewed, 2014)Background: A combined procedure of sleeve gastrectomy and duodenal switch (SG+DS) has been applied to the treatment of super obesity. The aim of the present study was to test whether duodenal switch alone (DS) leads to ... -
Effects of exercise intensity and nutrition advice on myocardial function in obese children and adolescents: a multicentre randomised controlled trial study protocol.
(Journal article; Peer reviewed, 2016)Introduction The prevalence of paediatric obesity is increasing, and with it, lifestyle-related diseases in children and adolescents. High-intensity interval training (HIIT) has recently been explored as an alternate to ... -
Effects of FKBP12-degrading PROTACs on receptor-specific TGF-β signaling in multiple myeloma
(Master thesis, 2021)Abstract Background and aims: Multiple myeloma (MM) is a form of cancer caused by the proliferation of aberrant plasma cells. Myeloma cells are addicted to the MYC oncogene, and this research group has previously shown ... -
Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
(Journal article; Peer reviewed, 2019)To address the shortcomings associated with corneal transplants, substantial efforts have been focused on developing new modalities such as xenotransplantion. Xenogeneic corneas are anatomically and biomechanically similar ... -
Effects of hexyl aminolevulinate and Amphinex based photodynamic therapy and photochemical internalization - in vitro studies using rat bladder cancer cells
(Master thesis, 2011)Photodynamic therapy (PDT) is a treatment modality which involves application of photosensitizers and their ability to accumulate selectively and damage cancer cells in presence of light. Light induced damage to cancer ... -
Effects of High Intensity Interval Training and Strenght Training on Metabolic, Cardiovascular and Hormonal Outcomes in Women with Polycystic Ovary Syndrome: A Pilot Study
(Journal article; Peer reviewed, 2015)Background: Polycystic ovary syndrome is a common endocrinopathy in reproductive-age women, and associates with insulin resistance. Exercise is advocated in this disorder, but little knowledge exists on the optimal ... -
Effects of hypoxia/reoxygenation and miR-24-3p in human cardiomyocyte models
(Master thesis, 2020)Background: Effective cardioprotective therapies targeting the reperfusion phase of ischemia/reperfusion (I/R) injury are lacking, which remain one of the top unmet clinical needs in cardiology. MicroRNAs (miRNAs) are a ... -
Effects of lost microRNA regulation at the global and single gene level in mammalian cells
(Doctoral thesis at NTNU;2014:307, Doctoral thesis, 2014) -
Effects of overexpressing NOR-1 on cell death and cell viability in human cardiomyocytes during doxorubicin-induced stress
(Master thesis, 2021)Koronar hjertesykdom er den ledende dødsårsaken i verden, karakterisert av redusert blodforsyning til hjertet. Ubehandlet kan dette føre til en fullstendig blokkering av koronararteriene, kjent som et hjerteinfarkt. ... -
Effects of photodynamic therapy by TPCS2a on glioma cell lines - in vitro and in vivo studies
(Master thesis, 2021)Ondartet glioma er en alvorlig sykdom som ofte er forbundet med en dårlig prognose. Fotodynamisk terapi (PDT) og fotokjemisk internalisering (PCI) er lovende terapeutiske prinsipper for økende eekt av gliomabehandling, ... -
Effects of Photodynamic Therapy on Protein Expressionin Rat Bladder Cancer Cells
(Master thesis, 2010)Photodynamic therapy (PDT) is an effective treatment involving light and a photosensitizer used in conjunction with molecular oxygen to elicit cell death. The purpose of this study is search for changes in protein expression ... -
Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants
(Journal article; Peer reviewed, 2018)Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; Infloran®) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely ...