Blar i Institutt for klinisk og molekylær medisin på tittel
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The Cyclooxygenase 2 inhibitor etoricoxib as adjunctive therapy in tuberculosis impairs macrophage control of mycobacterial growth
(Peer reviewed; Journal article, 2023)Background Current tuberculosis treatment regimens could be improved by adjunct host-directed therapies (HDT) targeting host responses. We investigated the antimycobacterial capacity of macrophages from patients with ... -
Cytochrome P-450 (CYP) inhibition by commercial Rhodiola rosea products in vitro and in humans
(Doctoral theses at NTNU;2017:244, Doctoral thesis, 2017)Cytokrom P-450 (CYP) inhibering av kommersielle Rhodiola rosea produkter in vitro og i mennesker. Rosenrot (Rhodiola rosea) er et populært naturprodukt med en global utbredelse. Tidligere studier har vist at naturprodukter ... -
Cytokine Network in Scrub Typhus: High Levels of Interleukin-8 Are Associated with Disease Severity and Mortality
(Journal article; Peer reviewed, 2014)Background: Scrub typhus, caused by Orientia tsutsugamushi, is endemic in the Asia-Pacific region. Mortality is high if untreated, and even with treatment as high as 10–20%, further knowledge of the immune response during ... -
Cytokine pattern in patients with ST-elevation myocardial infarction treated with the interleukin-6 receptor antagonist tocilizumab
(Peer reviewed; Journal article, 2023)Background Tocilizumab improves myocardial salvage index (MSI) in patients with ST-elevation myocardial infarction (STEMI), but its mechanisms of action are unclear. Here, we explored how cytokines were affected by tocilizumab ... -
Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond
(Peer reviewed; Journal article, 2021)Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ... -
Cytokine profiles and diagnoses in elderly, hospitalised psychiatric patients
(Journal article; Peer reviewed, 2018)Background There is a paucity of studies on inflammatory markers in elderly psychiatric patients. Hence, our study was undertaken to investigate cytokines as biomarkers in diagnostically unselected elderly patients admitted ... -
Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis
(Journal article; Peer reviewed, 2016)Human metapneumovirus (hMPV) causes severe airway infection in children that may be caused by an unfavorable immune response. The nature of the innate immune response to hMPV in naturally occurring infections in children ... -
Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases
(Journal article; Peer reviewed, 2018) -
Cytokine profiling as a measure of immunological development and deviation throughout pregnancy in healthy women and women with PCOS
(Doctoral theses at NTNU;2022:183, Doctoral thesis, 2022)Norsk sammendrag Cytokinprofilering som mål på immunologiske forandringer gjennom svangerskapet hos friske kvinner og kvinner med PCOS Mors immunsystem tilpasser seg gjennom de ulike fasene av svangerskapet for å sikre ... -
Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia
(Journal article; Peer reviewed, 2017)Background The inflammatory response to community-acquired pneumonia (CAP) is orchestrated through activation of cytokine networks and the complement system. We examined the association of multiple cytokines and the ... -
Cytokines in Relation to Motor Activity in an Acute Psychiatric Population
(Peer reviewed; Journal article, 2019)Background: Deviations in motor activity are important clinical features of several psychiatric disorders in an acute state. Immune activity is associated with several psychiatric disorders and may affect motor activity. ... -
Cytomegalovirus antibody status at 17 - 18 weeks of gestation and preeclampsia: a case-control study of pregnant women in Norway
(Journal article; Peer reviewed, 2012)Objective To assess the association between maternal cytomegalovirus (CMV) antibodies in mid-pregnancy and preeclampsia. Design Nested case–control study. Setting Pregnancies registered in the Norwegian Mother and ... -
Cytosolic Phospholipase A2 Alpha Regulates TLR Signaling and Migration in Metastatic 4T1 Cells
(Journal article; Peer reviewed, 2019)Metastatic disease is the leading cause of death in breast cancer patients. Disrupting the cancer cell’s ability to migrate may be a strategy for hindering metastasis. Cytosolic phospholipase A2 α (cPLA2α), along with ... -
Cytosolic scaffold functions of PCNA
(Doctoral theses at NTNU;2017:203, Doctoral thesis, 2017)PCNA som et plattform-protein i cytosol Kroppen vår består av millioner av celler som alle stammer fra en enkelt celle. For hver celledeling må arvestoffet, DNA-et, kopieres feilfritt i et samarbeid mellom mange ulike ... -
Cytotoxic Effect on Human Myeloma Cells and Leukemic Cells by the Agaricus blazei Murill Based Mushroom Extract, Andosan™
(Journal article; Peer reviewed, 2017)Agaricus blazei Murill is an edible mushroom of the Basidiomycetes family, which has been found to contain a number of compounds with antitumor properties, such as proteoglycans and ergosterol. In the present investigation, ... -
Cytotoxicity and effect on wound re-epithelialization after topical administration of tranexamic acid
(Journal article; Peer reviewed, 2019)Background Topical administration of tranexamic acid (TXA) reduces bleeding from surgical wounds similarly to intravenous use, but with negligible risk of adverse systemic events. Topical use is expanding, but is ... -
Cytotoxicity and repair of uracil and 5-fluorouracil in DNA
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:95, Doctoral thesis, 2011)Cytotoksisitet og reparasjon av uracil og 5-fluorouracil i DNA Vårt arvemateriale (gener) er organisert i 23 kromosompar, som det finnes fullstendige kopier av i storparten av våre celler. Hvert kromosom består av en lang ... -
Cytotoxicity of poly(Alkyl cyanoacrylate) nanoparticles
(Journal article; Peer reviewed, 2017)Although nanotoxicology has become a large research field, assessment of cytotoxicity is often reduced to analysis of one cell line only. Cytotoxicity of nanoparticles is complex and should, preferentially, be evaluated ... -
Dansk embryologikompendium
(Peer reviewed; Journal article, 2021)Kompendiet er først og fremst rettet mot medisinstudenter, men kan leses av alle med interesse for feltet eller ønske om en kort repetisjon av embryologien. Det er kortfattet og nærmest stikkordspreget, i A4-størrelse og ... -
Dasatinib induces fast and deep responses in newly diagnosed chronic myeloid leukaemia patients in chronic phase: Clinical results from a randomised phase-2 study (NordCML006)
(Journal article, 2015)We randomised 46 newly diagnosed patients with chronic myeloid leukaemia (median age 56) to receive dasatinib 100 mg QD or imatinib 400 mg QD and report outcome as an intention-to-treat analysis with 36 months follow-up. ...