Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 373-392 of 3426
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Broad-Spectrum Antiviral monotherapies: in silico drug repositioning against emergent viruses
(Master thesis, 2022)Utbruddet av SARS-CoV-2 har demonstrert realiteten av globale virale trusler. SARS-CoV-2 krysset arts barrierer og forårsaket en pandemi som verden ikke var forberedt på. Antiviraler er medikamenter som hemmer formeringen ... -
Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in nonhuman primates
(Peer reviewed; Journal article, 2023)The COVID-19 pandemic represents a global challenge that has impacted and is expected to continue to impact the lives and health of people across the world for the foreseeable future. The rollout of vaccines has provided ... -
Bronchial microdialysis monitoring of inflammatory response in open abdominal aortic aneurysm repair; an observational study.
(Journal article; Peer reviewed, 2017)Aortic surgery results in ischemia–reperfusion injury that induces an inflammatory response and frequent complications. The magnitude of the inflammatory response in blood and bronchi may be associated with the risk of ... -
Bronchoalveolar lavage fluid IFN- γ + Th17 cells and regulatory T cells in pulmonary sarcoidosis
(Journal article; Peer reviewed, 2014)In sarcoidosis, increased Th17 cell fractions have been reported in bronchoalveolar lavage fluid, and elevated numbers of Th17 cells producing IFN-𝛾 have been observed in peripheral blood. The balance between Th1, Th17, ... -
Bruk av botulinumtoksin A til barn med cerebral parese
(Peer reviewed; Journal article, 2019)BAKGRUNN Intramuskulære injeksjoner med botulinumtoksin A har i over 20 år vært en etablert behandling av spastisitet hos barn med cerebral parese. Vi undersøkte hvor mange barn med cerebral parese i Norge som får slik ... -
Bruk av piperacillin/tazobaktam ved behandling av infeksjoner i abdomen - Kan intervensjoner bidra til å optimalisere forskrivningen?
(Master thesis, 2022)Introduksjon: Antibiotikaresistens er en trussel mot folkehelsen. Effektive tiltak for å bremse utviklingen er viktig for å kunne ha effektiv antibiotikabehandling også i fremtiden. De nasjonale retningslinjene for ... -
Bruk av psykofarmaka der farmakogenetiske analyser er aktuelt
(Master thesis, 2022)Bakgrunn: En betydelig andel av den norske befolkningen vil rammes av psykiske lidelser i løpet av ett år, og mange vil ha behov for medikamentell behandling med psykofarmaka. Det er imidlertid flere utfordringer knyttet ... -
Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study
(Journal article; Peer reviewed, 2017)Background Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods We studied the burden of disease and death related to BSI in ... -
The burden of hospital-attended influenza in Norwegian children
(Journal article; Peer reviewed, 2022) -
The Burden of Human Bocavirus 1 in Hospitalized Children with Respiratory Tract Infections
(Peer reviewed; Journal article, 2023)Background Human bocavirus 1 (HBoV1) is frequently codetected with other viruses, and detected in asymptomatic children. Thus, the burden of HBoV1 respiratory tract infections (RTI) has been unknown. Using HBoV1-mRNA ... -
The Burden of Human Coronavirus in Norwegian Children hospitalized with Respiratory Tract Infections
(Doctoral theses at NTNU;2022:359, Doctoral thesis, 2022) -
The burden of respiratory syncytial virus in children under 5 years of age in Norway
(Peer reviewed; Journal article, 2021)Abstract Objectives To estimate age-specific incidence of medically attended respiratory syncytial virus (RSV) infections in hospitalised Norwegian children and describe disease epidemiology. Methods Active prospective ... -
The burden of rheumatoid arthritis - physical fitness, function, and mortality
(Doctoral theses at NTNU;2023:243, Doctoral thesis, 2023)Patients with rheumatoid arthritis (RA) have higher mortality rates than the general population as well as lower cardiorespiratory fitness. They also have an increased risk of myocardial infarction of similar magnitudes ... -
Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
(Journal article, 2017)Intravenously injected nanopharmaceuticals, including PEGylated nanoparticles, induce adverse cardiopulmonary reactions in sensitive human subjects, and these reactions are highly reproducible in pigs. Although the underlying ... -
Bystander memory T cells and IMiD/checkpoint therapy in multiple myeloma: A dangerous tango?
(Peer reviewed; Journal article, 2021)In this review article we discuss the role of the memory T cells in multiple myeloma (MM) and how they may influence immune responses in patients that received immunomodulating drugs and check point therapy -
Bør vi spise mer fisk – eller mindre?
(Journal article; Peer reviewed, 2023) -
C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
(Journal article; Peer reviewed, 2018)The chemokine C-C motif ligand 20 (CCL20) is increased in the colonic mucosa during active inflammatory bowel disease (IBD) and can be found both in the epithelium and immune cells in the lamina propria. The present study ... -
c-Myb Binding Sites in Haematopoietic Chromatin Landscapes
(Journal article, 2015)Strict control of tissue-specific gene expression plays a pivotal role during lineage commit- ment. The transcription factor c-Myb has an essential role in adult haematopoiesis and func- tions as an oncogene when rearranged ... -
Caesarean birth experiences. A qualitative study from Sierra Leone.
(Journal article; Peer reviewed, 2019)Background Positive birth experiences lead to better postnatal functioning, and influence mode of delivery choice for subsequent pregnancies. Healthcare workers can influence the birth experience through relevant support ... -
Caesarean section in women with axial spondyloarthritis and psoriatic arthritis: a population-based study
(Peer reviewed; Journal article, 2023)Background There is sparse documentation on pregnancy outcomes in women with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). Data on disease activity are often lacking, preventing the direct investigation ...