Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 310-329 av 3426
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Benzoic Acid-Inducible Gene Expression in Mycobacteria
(Journal article; Peer reviewed, 2015)Conditional expression is a powerful tool to investigate the role of bacterial genes. Here, we adapt the Pseudomonas putida-derived positively regulated XylS/Pm expression system to control inducible gene expression in ... -
Bereaved parents’ quality of life: resilience and professional support
(Peer reviewed; Journal article, 2021)Objectives: The study aimed to compare the quality of life (QoL) among cancer-bereaved parents with a control group and explore how resilience and support from healthcare professionals associated with QoL of parents 2–8 ... -
Bestemmelse av fosfolipidnivåer i EGF-behandlede brystkreftceller dyrket in vitro med hjelp av MALDI-MSI
(Master thesis, 2022)Brystkreft er i dag den vanligste kreftrelaterte dødsårsaken blant kvinner i verden. Til tross for gode prognoser for de fleste molekylære undergruppene av brystkreft, er det også noen grupper som har svært dårlig prognose. ... -
Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation
(Peer reviewed; Journal article, 2021)Background Glucocorticoids (GCs) play a pivotal role in fetal programming. Antenatal treatment with synthetic GCs (sGCs) in individuals in danger of preterm labor is common practice. Adverse short- and long-term effects ... -
Better tolerance of preservative-free latanoprost compared to preserved glaucoma eye drops: The 12-month real-life FREE study
(Journal article; Peer reviewed, 2018)Background: Lack of efficacy due to bad compliance caused by intolerance issues is the main reason for a change to a better tolerated ocular treatment, such as using preservative-free (PF) eye drops. Aim: To assess the ... -
Betydningen av depresjon hos kvinner som får fertilitetsbehandling
(Master thesis, 2023)Studiemål: Vi hadde som mål å undersøke om kvinner i behandling for depresjon før eller under behandling med assistert befruktning har like stor sannsynlighet til å oppnå biokjemisk graviditet, klinisk graviditet og å føde ... -
Biases in second-trimester ultrasound dating related to prediction models and fetal measurements
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:4, Doctoral thesis, 2012)FEILKILDER VED ULTRALYD-BASERT TERMINFASTSETTELSE I 2. TRIMESTER, RELATERT TIL PREDIKSJONSMETODER OG MÅLINGER Rutineundersøkelsen med ultralyd rundt svangerskapsuke 17–19 har vært en viktig del av norsk svangerskapsomsorg ... -
The bidirectional association between depressive symptoms, assessed by the HADS, and albuminuria-A longitudinal population-based cohort study with repeated measures from the HUNT2 and HUNT3 Study
(Peer reviewed; Journal article, 2022)Background Both albuminuria and depression are associated with cardiovascular disease, reflecting low-grade systemic inflammation and endothelial dysfunction. They share risk factors including weight, blood pressure, ... -
The Bihormonal Artificial Pancreas: New Perspectives on the Pharmacokinetics and Pharmacodynamics of Glucagon
(Doctoral theses at NTNU;2023:106, Doctoral thesis, 2023)Diabetes mellitus type 1 is an autoimmune disease that causes selective destruction of the insulin-producing β-cells in the pancreatic islet of Langerhans. Insulin induces glucose storage and reduces blood glucose ... -
Bilirubin estimates from smartphone images of newborn infants’ skin correlated highly to serum bilirubin levels
(Peer reviewed; Journal article, 2020)Aim Neonatal jaundice is an important cause of morbidity and mortality, and identifying the condition remains a challenge. This study evaluated a novel method of estimating bilirubin levels from colour‐calibrated ... -
Bioaktive lipofile stoffer og deres effekt på inflammasjon i SH-SY5Y celler.
(Master thesis, 2019)Bakgrunn: Nevrodegenerative sykdommer (ND) defineres som forstyrrelser i sentrale- og perifere nervesystemet. Kronisk inflammasjon og svikt i mitokondrier er faktorer som er involvert i nevrologiske lidelser. Tetradecylt ... -
Biochemical profiling of diabetes disease progression by multivariate vibrational microspectroscopy of the pancreas
(Journal article; Peer reviewed, 2017)Despite the dramatic increase in the prevalence of diabetes, techniques for in situ studies of the underlying pancreatic biochemistry are lacking. Such methods would facilitate obtaining mechanistic understanding of diabetes ... -
Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism
(Peer reviewed; Journal article, 2016)Cytosine methylation in CpG dinucleotides is an epigenetic DNA modification dynamically established and maintained by DNA methyltransferases and demethylases. Molecular mechanisms of active DNA demethylation began to surface ... -
Biocompatibility and Biotolerability Assessment of Microspheres Using a Whole Blood Model
(Journal article, 2013)The whole blood model is a powerful method to determine the immediate inflammatory reactions towards foreign objects in general. This review focuses on the use of a lepirudin based whole blood model for evaluating microspheres ... -
Biodegradation of Dispersed Oil in natural Seawaters from Western Greenland and a Norwegian fjord
(Journal article; Peer reviewed, 2018)With increasing oil exploration, production and transportation in the Arctic, predictions of the fate of spilled oil become important, including oil compound biodegradation. The use of chemical dispersants may result in ... -
Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft
(Peer reviewed; Journal article, 2021)We have investigated the biodistribution and tumor macrophage infiltration after intravenous injection of the poly(alkyl cyanoacrylate) nanoparticles (NPs): PEBCA (poly(2-ethyl-butyl cyanoacrylate), PBCA (poly(n-butyl ... -
Biomarker discovery in multiple myeloma progression by quantitative proteomics
(Doctoral theses at NTNU;2018:305, Doctoral thesis, 2018)SAMMENDRAG Myelomatose (multipel myelom, benmargskreft) er en krefttype som skyldes ukontrollert vekst av plasmaceller i benmarg. Det er den nest vanligste hematologiske kreftformen og rammer ca. 300 personer i Norge hvert ... -
Biomarker discovery using NMR based metabolomics of tissue
(Journal article; Peer reviewed, 2019)NMR-based metabolomics has shown promise in the diagnosis of diseases as it enables identification and quantification of metabolic biomarkers. Using high-resolution magic-angle-spinning (HR-MAS) NMR spectroscopy, metabolic ... -
Biomarkers of Subclinical Atherosclerosis
(Master thesis, 2021)Bakgrunn: Tradisjonelle risikomarkørar nytta for å estimere risiko for hjarteinfarkt forklarar berre ein del av dei faktiske tilfella. Med ein auka førekomst av tilfelle er det behov for nye risikomarkørar som kan forbetre ...