Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 2990-3009 av 3426
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Symphysis-fundus height measurement to predict small-for-gestational-age status at birth: A systematic review
(Journal article; Peer reviewed, 2015)Background: Fetal growth restriction is among the most common and complex problems in modern obstetrics. Symphysis-fundus (SF) height measurement is a non-invasive test that may help determine which women are at risk. ... -
Symptom management in patients with advanced cancer and the role of computer assistance
(Doctoral thesis at NTNU;2015:307, Doctoral thesis, 2015)Norwegian Summary: Pasienter med langtkommet kreft opplever en rekke symptomer. Disse symptomene er ofte underrapportert og underbehandlet. For å håndtere disse symptomene anbefales systematisk kartlegging og klassifisering, ... -
Symptomatic primary (Al) amyloidosis of the stomach and duodenum.
(Journal article; Peer reviewed, 2013)Primary (AL) amyloidosis of the gastrointestinal tract is relatively rare, and symptomatic amyloidosis of the stomach is even more seldom. We present the case of a patient who was referred to upper endoscopy because of ... -
Symptoms in patients receiving opioids for cancer pain: clinical and pharmacogenetic aspects
(Doktoravhandlinger ved NTNU, 1503-8181; 2011:189, Doctoral thesis, 2011)Forekomsten av kreft er økende i industrialiserte deler av verden. Symptomer som smerte, fatigue, obstipasjon, kvalme, oppkast, depresjon og søvnvansker er hyppige og kan oppstå i ulike stadier av kreftsykdom. Det er store ... -
Symptoms in the general Norwegian adult population - prevalence and associated factors
(Peer reviewed; Journal article, 2020)Background Patients´ own perceptions and evaluations of symptoms, functioning and other health-related factors, i.e. Patient Reported Outcomes (PROs), are important elements for providing good patient care. Symptoms are ... -
Symptoms of depression and risk of abdominal aortic aneurysm: A HUNT study
(Journal article; Peer reviewed, 2019)Background Depression is associated with cardiovascular diseases, but the evidence is scarce regarding depression and risk of abdominal aortic aneurysms (AAA). The aim was to determine whether individuals with depressive ... -
Symptoms – prevalence and electronic assessment
(Doctoral theses at NTNU;2020:352, Doctoral thesis, 2020)Symptomer er definert som en subjektiv opplevelse av sykdomstegn som bare kan oppleves og iakttas av den syke selv. En rekke forskjellige symptomer er vanlige i en generell befolkning, utgjør en hyppig årsak for kontakt ... -
Synaptic input as a directional cue for migrating interneuron precursors
(Journal article; Peer reviewed, 2017)During CNS development, interneuron precursors have to migrate extensively before they integrate in specific microcircuits. Known regulators of neuronal motility include classical neurotransmitters, yet the mechanisms that ... -
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
(Journal article; Peer reviewed, 2015)Ogg1 and Mutyh DNA glycosylases cooperate to prevent mutations caused by 8-oxoG, a major premutagenic DNA lesion associated with cognitive decline. We have examined behavior and cognitive function in mice deficient of these ... -
Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections
(Journal article; Peer reviewed, 2021)Background: There is an urgent need for new antivirals with powerful therapeutic potential and tolerable side effects. Methods: Here, we tested the antiviral properties of interferons (IFNs), alone and with other drugs in ... -
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer
(Journal article; Peer reviewed, 2012)Expression of p53 appears to be correlated to prognosis in patients with malignancy, but its role in gastric carcinoma has remained controversial. Recently we reported that JWA, an ADP-ribosylation-like factor 6 interacting ... -
Syntese av fenylpropanoider ved bruk av trekomponentsyntese med Bestmann-ylid
(Master thesis, 2022)Fenylpropanoider er plante sekundærmetabolitter og har i de siste årene fått oppmerksomhet da de har vist forskjellige biologiske effekter. Målet for dette master prosjektet var å danne et kjemisk bibliotek av fenylpropanoid ... -
Syntetiske studier av chrysogeamide A og B
(Master thesis, 2020)En av de største utfordringene i dagens samfunn er utviklingen av antibiotikaresistens hos bakterier. For å forhindre at bakterielle infeksjoner blir like dødelig som før oppdagelsen av antibiotika er det helt avgjørende ... -
Synthesis of Scopularide A and B
(Master thesis, 2020)Scopularid A og B er en del av en familie av sykloheksadepsipeptider som har vist å ha betydelig effekt mot tumorvekst hos visse typer kreftceller. For å studere denne effekten i større detalj, så har det blitt utprøvd en ... -
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
(Peer reviewed; Journal article, 2019)The global spread of antimicrobial resistance and the increasing number of immune‐compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host ... -
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
(Peer reviewed; Journal article, 2019)The global spread of antimicrobial resistance and the increasing number of immune‐compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host ... -
Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53
(Journal article; Peer reviewed, 2019)Non-homologous end joining (NHEJ) is a DNA repair pathway that senses, processes and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. During NHEJ, core Ku70 and Ku80 subunits bind DSBs as a heterodimer ... -
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70
(Journal article; Peer reviewed, 2017)DNA double-strand breaks (DSBs) are recognized and repaired by the Classical Non-Homologous End-Joining (C-NHEJ) and Homologous Recombination pathways. C-NHEJ includes the core Ku70 and Ku80 (or Ku86) heterodimer that binds ... -
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
(Peer reviewed; Journal article, 2022)Bacterial and mitochondrial DNA, sharing an evolutionary origin, act as danger-associated molecular patterns in infectious and sterile inflammation. They both contain immunomodulatory CpG motifs. Interactions between CpG ... -
Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents
(Peer reviewed; Journal article, 2021)Imidazopyridinones and 7-azaoxindoles are two classes of heterocyclic compounds with only limited previous use in organic and medicinal chemistry. Various synthetic methods and routes have been evaluated to identify safe ...