Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 2033-2052 av 3585
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Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions
(Peer reviewed; Journal article, 2022)Environmental stressors such as repeated social defeat may initiate powerful activation of subconscious parts of the brain. Here, we examine the consequences of such stress (induced by resident-intruder paradigm) on the ... -
Mapping population access to essential surgical care in Liberia using equipment, personnel, and bellwether capability standards
(Journal article; Peer reviewed, 2022)Background: Accurate surveillance of population access to essential surgery is key for strategic healthcare planning. This study aimed to estimate population access to surgical facilities meeting standards for safe surgery ... -
Mapping post - translational histone modifications and the TH2B variant in spermatogenesis
(Master thesis, 2012)Epigenetics has been defined by Goldberg et al. [1] as the study of heritable changes in gene expression or cellular phenotype which arises without changes in the DNA sequence. Post-translational histone modification and ... -
Mapping the human genetic architecture of COVID-19
(Journal article; Peer reviewed, 2021)The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity ... -
Markers of autoimmunity in Latent Autoimmune Diabetes in Adults (LADA) and non-diabetic adults: Impact in phenotype and genetic predisposition: Results from the Nord-Trøndelag health study
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:113, Doctoral thesis, 2013)Diabetes is mainly classified: type 1 and type 2 diabetes. Type 1 diabetes is an autoimmune disease in which the body's immune system attacks and destroys the beta cells that produce insulin. Patients with type 2 diabetes ... -
Markers of endothelial glycocalyx dysfunction in Clarkson disease
(Peer reviewed; Journal article, 2022)Background Clarkson disease (monoclonal gammopathy-associated idiopathic systemic capillary leak syndrome, ISCLS) is a rare idiopathic condition marked by transient, relapsing-remitting episodes of systemic microvascular ... -
Markers of Kidney Tubular Secretion and Risk of Adverse Events in SPRINT Participants with CKD
(Peer reviewed; Journal article, 2022)Significance Statement SPRINT demonstrated in individuals with hypertension and high cardiovascular disease (CVD) risk that intensive BP lowering was associated with decreased risk of CVD events and all-cause mortality. ... -
Markers of placental insufficiency: etiology and the risk of cerebral palsy:Population based studies of preeclampsia, low birth weight, and abnormal placental weight
(Doctoral thesis at NTNU;2015:172, Doctoral thesis, 2015)Placental insufficiency may be defined as a placenta not able to perform its central tasks; namely, delivery of sufficient oxygen and nutrients to the developing fetus. In this thesis, preeclampsia, fetal growth restriction ... -
Mass spectrometry for the evaluation of monoclonal proteins in multiple myeloma and related disorders: an International Myeloma Working Group Mass Spectrometry Committee Report
(Peer reviewed; Journal article, 2021)Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ... -
Massive parallel amplicon sequencing of the mismatch repair genes MSH2, MSH6, MLH1 and PMS2. Implementation of hereditary and non-hereditary subtypes of colorectal cancer
(Master thesis, 2013) Colorectal cancer is the one of the most frequent malignancies and accounts for approximately 3500 new cases each year in Norway. Colorectal cancer is a heterogeneous disorder and can be divided into three main groups: ... -
Maternal alcohol and drug use during pregnancy affects the motor behaviour and general movements of infants aged 3–4 months
(Peer reviewed; Journal article, 2020)Background Exposure of alcohol and/or other addictive drugs in pregnancy is a documented risk factor for later neurological impairment. Aims The aim of the study was to determine whether infants suffering from prenatal ... -
Maternal exposure to childhood maltreatment and mental and behavioral disorders in children
(Peer reviewed; Journal article, 2022)Exposure to maltreatment in childhood is associated with lifelong risk of mental and behavioral disorders. Whether the effects extend to the next generation remains unclear. We examined whether maternal exposure to childhood ... -
Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the pregnancy and childhood epigenetics consortium
(Peer reviewed; Journal article, 2021)Altered maternal haemoglobin levels during pregnancy are associated with pre-clinical and clinical conditions affecting the fetus. Evidence from animal models suggests that these associations may be partially explained by ... -
Maternal mental health and adverse birth outcomes
(Peer reviewed; Journal article, 2022)Recent research in economics emphasizes the role of in utero conditions for the health endowment at birth and in early childhood and for social as well as economic outcomes in later life. This paper analyzes the relation ... -
Maternal PCOS status and metformin in pregnancy: Steroid hormones in 5–10 years old children from the PregMet randomized controlled study
(Peer reviewed; Journal article, 2021)Objective Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with potential effects on offspring both genetically and through altered intrauterine environment. Metformin, which ameliorate hormonal disturbances ... -
Maternal pre-pregnancy overweight and gestational diabetes and dietary intakes among young adult offspring
(Peer reviewed; Journal article, 2020)Background/Objectives Maternal pre-pregnancy overweight/obesity and gestational diabetes (GDM) are associated with increased fat deposition in adult offspring. The purpose of this study was to identify if maternal ... -
Maternal serum levels of prokineticin-1 related to pregnancy complications and metformin use in women with polycystic ovary syndrome: a post hoc analysis of two prospective, randomised, placebo-controlled trials
(Peer reviewed; Journal article, 2023)Objective Serum prokineticin-1 (s-PROK1) in the second and third trimester of pregnancy is positively correlated to preeclampsia, intrauterine growth restriction (IUGR) and preterm delivery. Women with polycystic ovary ... -
Maternal serum retinol, 25(OH)D and 1,25(OH)2D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up
(Journal article; Peer reviewed, 2019)Background Vitamin A and D deficiency is prevalent in pregnant women worldwide. Both vitamins are involved in fetal skeletal development. A positive association between maternal vitamin D levels and offspring bone mineral ... -
Maternal vitamin D status in pregnancy and molar incisor hypomineralisation and hypomineralised second primary molars in the offspring at 7–9 years of age: a longitudinal study
(Peer reviewed; Journal article, 2022)Purpose The study aimed to investigate associations between maternal vitamin D status during pregnancy and molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPM) among children. Methods The ...