Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1983-2002 av 3426
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Met and unmet needs for surgery in Sierra Leone: A comprehensive, retrospective, countrywide survey from all health care facilities performing operations in 2012
(Journal article; Peer reviewed, 2015) -
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation
(Journal article; Peer reviewed, 2008)Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good prognosis, and identify patients likely ... -
Meta-analysis of the human leukocyte antigen-G (HLA-G) 14bp insertion/deletion polymorphism as a risk factor for preeclampsia
(Journal article; Peer reviewed, 2015)The non-classical major histocompatibility complex, human leukocyte antigen (HLA)-G, plays an important role in pregnancy. HLA-G mediates proper interaction between maternal immune cells and fetal trophoblasts invading the ... -
Metabolic adaptation is an illusion, only present when participants are in negative energy balance
(Peer reviewed; Journal article, 2020)Background The existence of metabolic adaptation, following weight loss, remains a controversial issue. To our knowledge, no study has evaluated the role of energy balance (EB) in modulating metabolic adaptation. Obj ... -
Metabolic adaptation is associated with less weight and fat mass loss in response to low-energy diets
(Peer reviewed; Journal article, 2021)Background: The practical relevance of metabolic adaptation remains a controversial issue. To the best of our knowledge, no study has properly evaluated the role of metabolic adaptation in modulating weight loss outcomes. ... -
Metabolic and transcriptional profiling of Arabidopsis thaliana fou2 mutant
(Master thesis, 2010)Glucosinolates (GSL) are important secondary metabolites found mainly in the Brassicaceae plant family. Jasmonic acid (JA) and its derivatives (JAs) are biologically active molecules playing important role in cell signaling. ... -
Metabolic changes in psoriatic skin under topical corticosteroid treatment
(Journal article; Peer reviewed, 2013)Background: MR spectroscopy of intact biopsies can provide a metabolic snapshot of the investigated tissue. The aim of the present study was to explore the metabolic pattern of uninvolved skin, psoriatic skin and ... -
Metabolic characterization of locally advanced breast cancer in response to NAC treatment based on HR MAS MRS
(Master thesis, 2013)Breast cancer is the most frequent cancer disease among women globally. Locally advanced breast cancer (LABC) consists of different groups of breast cancer patients with variable prognosis. Today’s treatment decision is ... -
Metabolic characterization of triple negative breast cancer
(Journal article; Peer reviewed, 2014)Background The aims of this study were to characterize the metabolite profiles of triple negative breast cancer (TNBC) and to investigate the metabolite profiles associated with human epidermal growth factor receptor-2/neu ... -
Metabolic profiles of brain metastases
(Journal article; Peer reviewed, 2013)Metastasis to the brain is a feared complication of systemic cancer, associated with significant morbidity and poor prognosis. A better understanding of the tumor metabolism might help us meet the challenges in controlling ... -
Metabolic profiles of placenta in preeclampsia using HR-MAS MRS metabolomics
(Journal article; Peer reviewed, 2015)Introduction Preeclampsia is a heterogeneous gestational disease characterized by maternal hypertension and proteinuria, affecting 2–7% of pregnancies. The disorder is initiated by insufficient placental development, ... -
Metabolic profiling of colorectal cancer organoids: A comparison between high-resolution magic angle spinning magnetic resonance spectroscopy and solution nuclear magnetic resonance spectroscopy of polar extracts
(Peer reviewed; Journal article, 2022)Patient-derived cancer cells cultured in vitro are a cornerstone of cancer metabolism research. More recently, the introduction of organoids has provided the research community with a more versatile model system. Physiological ... -
Metabolic response to everolimus in patient-derived triple negative breast cancer xenografts
(Journal article; Peer reviewed, 2017)Patients with triple-negative breast cancer (TNBC) are unresponsive to endocrine and anti-HER2 pharmacotherapy, limiting their therapeutic options to chemotherapy. TNBC is frequently associated with abnormalities in the ... -
Metabolic syndrome and esophageal and gastric cancer
(Journal article; Peer reviewed, 2015)Background The role of the metabolic syndrome in the etiology of esophageal and gastric cancer is unclear. Methods This was a large nationwide cohort study based on data from 11 prospective population-based cohorts ... -
Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA
(Journal article, 2017)The mitochondrial DNA (mtDNA) resides in the vicinity of energy-rich reactions. Thus, chemical modifications of mtDNA might mirror mitochondrial processes and could serve as biomarkers of metabolic processes in the ... -
Metabolite and lipoprotein responses and prediction of weight gain during breast cancer treatment
(Journal article; Peer reviewed, 2018)Background Breast cancer treatment has metabolic side effects, potentially affecting risk of cardiovascular disease (CVD) and recurrence. We aimed to compare alterations in serum metabolites and lipoproteins during treatment ... -
Metabolite profiling of ortho-, meta- and para-fluorofentanyl by hepatocytes and high-resolution mass spectrometry
(Peer reviewed; Journal article, 2019)New psychoactive substances are emerging on the illegal drug market. Synthetic opioids including fentanyl analogues are of special concern due to their high potency. This indicates the possibility of low drug concentrations ... -
Metabolomic biomarkers in serum and urine in women with preeclampsia
(Journal article, 2014)Objective To explore the potential of magnetic resonance (MR) metabolomics for study of preeclampsia, for improved phenotyping and elucidating potential clues to etiology and pathogenesis. Methods Urine and serum ... -
Metabolomic Biomarkers of Preeclampsia: An NMR Protocol Development and Pilot Study
(Master thesis, 2012)Preeclampsia is a serious complication of pregnancy, which presents risk to both the expectant mother and to the fetus. It affects 3-8% of pregnancies, resolves only upon delivery, and is a major cause of preterm birth. ... -
Metabolomic profiling reveals distinct and mutual effects of diet and inflammation in shaping systemic metabolism in LDLR<sup>−/−</sup> mice
(Journal article; Peer reviewed, 2020)