Blar i Institutt for klinisk og molekylær medisin på tittel

Viser treff 1165-1184 av 3426

    • FastPathology: An open-source platform for deep learning-based research and decision support in digital pathology 

      Pedersen, André; Valla, Marit; Bofin, Anna Mary; Perez de Frutos, Javier; Reinertsen, Ingerid; Smistad, Erik (Peer reviewed; Journal article, 2021)
      Deep convolutional neural networks (CNNs) are the current state-of-the-art for digital analysis of histopathological images. The large size of whole-slide microscopy images (WSIs) requires advanced memory handling to read, ...

    • The fat mass and obesity-associated (FTO) gene allele rs9939609 and glucose tolerance, hepatic and total insulin sensitivity, in adults with obesity 

      De Soysa, Ann Kristin Hjelle; Langaas, Mette; Jakic, Anida; Shojaee-Moradie, Fariba; Umpleby, A. Margot; Grill, Valdemar Erik Robert; Mostad, Ingrid Løvold (Peer reviewed; Journal article, 2021)
      The objective of the study was to assess associations of the rs9939609 FTO allele to glucose tolerance, hepatic and total insulin sensitivity (IS) in individuals with obesity. From a low-dose hyperinsulinemic euglycemic ...

    • Fatigue Following Pediatric Acquired Brain Injury: Interplay With Associated Factors in a Clinical Trial Population Compared to Healthy Controls 

      Hypher, Ruth Elizabeth; Andersson, Stein; Finnanger, Torun Gangaune; Brandt, Anne Elisabeth; Hoorelbeke, Kristof; Lie, Hanne Cathrine; Barder, Helene; Larsen, Selma Mujezinovic; Risnes, Kari; Rø, Torstein Baade; Stubberud, Jan (Peer reviewed; Journal article, 2021)
      Objective: The aims of the present study were to compare fatigue levels in children with pediatric acquired brain injury (pABI) with healthy controls (HCs), and examine the interplay of fatigue with associated factors. ...

    • Fatigue in cancer treatment - assessment, course and etiology 

      Knobel, Heidi (Doktoravhandlinger ved NTNU, 1503-8181; 2007:138, Doctoral thesis, 2007)
      Aims. The major aims of the present work were to increase the understanding of cancer related fatigue with respect to assessment methodology, frequency and possible etiology. The validity of two fatigue instruments was ...

    • Fatigue in young adults with juvenile idiopathic arthritis 18 years after disease onset: data from the prospective Nordic JIA cohort 

      Arnstad, Ellen Dalen; Glerup, Mia; Rypdal, Veronika Gjertsen; Peltoniemi, Suvi; Fasth, Anders; Nielsen, Susan; Zak, Marek; Aalto, Kristiina; Berntson, Lillemor; Nordal, Ellen Berit; Herlin, Troels; Romundstad, Pål Richard; Rygg, Marite (Journal article; Peer reviewed, 2021)
      Background: To study fatigue in young adults with juvenile idiopathic arthritis (JIA) 18 years after disease onset, and to compare with controls. Methods: Consecutive children with onset of JIA between 1997 and 2000, from ...

    • Fatty Acids Composition and HIV Infection: Altered Levels of n-6 Polyunsaturated Fatty Acids Are Associated with Disease Progression 

      Ueland, Thor; Waagsbø, Bjørn; Berge, Rolf Kristian; Trøseid, Marius; Aukrust, Pål; Damås, Jan Kristian (Peer reviewed; Journal article, 2023)
      Fatty acids (FAs) are important regulators of immune responses and innate defense mechanisms. We hypothesized that disturbed FA metabolism could contribute to the progression of HIV infection. Plasma levels of 45 FAs were ...

    • Fear of hypoglycaemia and its relation to hypoglycaemia awareness and symptom intensity in Type 1 diabetes 

      Hatle, Håvard; Bjørgaas, Marit Ragnhild Rokne; Rø, Torstein Baade; Olsen, Sandra Elise; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)
      Aims To investigate fear of hypoglycaemia (FoH) in relation to hypoglycaemia awareness, history of severe hypoglycaemia (SH) and hypoglycaemia symptoms in adults with Type 1 diabetes. Methods Questionnaire-based ...

    • Feasibility and accuracy of point-of-care pocket-size ultrasonography performed by medical students 

      Andersen, Garrett Newton; Viset, Annja Torlaug; Mjølstad, Ole Christian; Salvesen, Øyvind; Dalen, Håvard; Haugen, Bjørn Olav (Journal article; Peer reviewed, 2014)
      Background Point-of-care ultrasound performed by clinicians is a useful supplement in the treatment and assessment of patients. We aimed to investigate whether medical students with minimal training were able to successfully ...

    • Feasibility of contrast-enhanced MRI derived textural features to predict overall survival in locally advanced breast cancer. 

      Chronaiou, Ioanna; Giskeødegård, Guro F.; Goa, Pål Erik; Teruel, Jose; Hedayati, Roja; Lundgren, Steinar; Huuse, Else Marie; Pickles, Martin D.; Gibbs, Peter; Sitter, Beathe; Bathen, Tone Frost (Journal article; Peer reviewed, 2019)
      Background The prognosis for women with locally advanced breast cancer (LABC) is poor and there is a need for better treatment stratification. Gray-level co-occurrence matrix (GLCM) texture analysis of magnetic resonance ...

    • Feasibility of early meal detection based on abdominal sound. 

      Kölle, Konstanze; Fougner, Anders Lyngvi; Ellingsen, Reinold; Carlsen, Sven Magnus; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Background In classical approaches for an artificial pancreas, continuous glucose monitoring (CGM) is the only measured variable used for insulin dosing and additional control functions. The CGM values are subject to time ...

    • Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function. 

      Ehsani, Rezvan; Bahrami, Shahram; Drabløs, Finn Sverre (Peer reviewed; Journal article, 2016)
      Background Transcription factors are key proteins in the regulation of gene transcription. An important step in this process is the opening of chromatin in order to make genomic regions available for transcription. Data ...

    • Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease 

      Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bergh, Kåre; Østvik, Ann Elisabet; Sandvik, Arne Kristian (Journal article; Peer reviewed, 2017)
      Background and Aim Accurate, noninvasive biomarkers are needed to diagnose and monitor inflammatory bowel disease (IBD). Neutrophil gelatinase-associated lipocalin (NGAL), also known as lipocalin 2, is expressed in inflamed ...

    • Feeding Behavior and Body Weight Development:: Lessons from Rats 

      Furnes, Marianne W. (Doktoravhandlinger ved NTNU, 1503-8181; 2008:251, Doctoral thesis, 2008)
      Background and aim Strains of rats in use today are derived almost exclusively from the Norway rat. Common outbred stocks are Wistar, Long-Evans and Sprague-Dawley, which are believed to better mimic the diverse genetics ...

    • Felles referanseområder for antiepileptika 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2017)
      Antiepileptika er grunnsteinen i behandlingen av epilepsi og brukes også ved en rekke andre indikasjoner. Serumkonsentrasjonsmåling av antiepileptika har hatt lang tradisjon som hjelpemiddel i behandling av epilepsi i ...

    • Fetal and perinatal implications of anomalies in the gastrointestinal tract and the abdominal wall 

      Brantberg, Anne (Doktoravhandlinger ved NTNU, 1503-8181; 2007:113, Doctoral thesis, 2007)
      Studien tar for seg tilstandene gastroschise og omfalocele, som er forskjellige former for bukveggsdefekter samt utviklingsavvik som gir forsnevringer på ulike nivå i fordøyelseskanalen: spiserør (øsofagusobstruksjon), ...

    • Fetal growth and birth anthropometrics in metformin exposed offspring born to mothers with PCOS 

      Hjorth-Hansen, Anna; Salvesen, Øyvind; Hanem, Liv Guro Engen; Eggebø, Torbjørn Moe; Salvesen, Kjell Å; Vanky, Eszter; Ødegård, Rønnaug (Journal article; Peer reviewed, 2017)
      Context Metformin is used in an attempt to reduce pregnancy complications associated with polycystic ovary syndrome (PCOS). Little is known about the effect of metformin on fetal development and growth. Objectives To ...

    • Fetal head descent assessed by transabdominal ultrasound: a prospective observational study 

      Kamel, Rasha; Negm, Sherif; Badr, Islam; Kahrs, Birgitte Heiberg; Eggebø, Torbjørn M.; Iversen, Johanne Kolvik von Ely (Peer reviewed; Journal article, 2021)
      Background Detection of copy number variation (CNV) in genes associated with disease is important in genetic diagnostics, and next generation sequencing (NGS) technology provides data that can be used for CNV detection. ...

    • Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia 

      Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M.; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero Olavi; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel; Kere, Juha (Peer reviewed; Journal article, 2020)
      Background Fetal immune tolerance is crucial for pregnancy success. We studied the link between preeclampsia, a severe pregnancy disorder with uncertain pathogenesis, and fetal human leukocyte antigen G (HLA-G) and other ...

    • Fetal molding examined with transperineal ultrasound and associations with position and delivery mode 

      Iversen, Johanne Kolvik; Kahrs, Birgitte Heiberg; Torkildsen, Erik A.; Eggebø, Torbjørn Moe (Journal article; Peer reviewed, 2020)
      Background To accommodate passage through the birth canal, the fetal skull is compressed and reshaped, a phenomenon known as molding. The fetal skull bones are separated by membranous sutures that facilitate compression ...

    • FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis 

      Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2017)
      Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...