Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1126-1145 av 3426
-
Exploring the role of the immunoglobulin-like receptor SLAMF1 in infection with human metapneumovirus
(Master thesis, 2021)Humant metapneumovirus (HMPV) er en ledende årsak til nedre luftveisinfeksjon. Generelt finnes det lite informasjon om hvordan HMPV entrer (infiserer), etablerer replikasjon og induserer immunresponser. Nylige funn fra en ... -
Exploring the role of TLR8 as a sensor in bacterial infections
(Doctoral theses at NTNU;2019:382, Doctoral thesis, 2019) -
Exploring the viability of measuring zinc and prostate-specific antigen in urine as a diagnostic tool for prostate cancer
(Master thesis, 2021)Bakgrunn: Nåværende metoder for å diagnostisere prostatakreft benytter seg av inngripende biopsier, som kan føre til komplikasjoner som infeksjon og død. Ikke-inngripende metoder benytter seg av PSA målinger, som ofte er ... -
Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice
(Journal article; Peer reviewed, 2015)Type 1 diabetes mellitus (T1DM) is an autoimmune destruction of insulin producing pancreatic beta-cells due to a genetic predisposition and can be triggered by environmental factors. We have previously shown that bisphenol ... -
Express Team-Based Learning (eTBL): A Time-Efficient TBL Approach in Neuroradiology
(Peer reviewed; Journal article, 2019)Rationale and Objectives Team-based learning (TBL) is a student-centred, teacher-directed instructional method that promotes active learning. The application phase of TBL stimulates group discussion and critical thinking, ... -
Expression and clinical significance of the proliferation marker minichromosome maintenance protein 2 (Mcm2) in diffuse astrocytomas WHO grade II
(Journal article; Peer reviewed, 2013)Background The WHO classification system for astrocytomas is not considered optimal, mainly because of the subjective assessment of the histopathological features. Few prognostic variables have been found that stratify ... -
Expression and clinical value of EGFR in human meningiomas
(Journal article; Peer reviewed, 2017)Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal ... -
Expression and function of FSTL5 in multiple myeloma cells
(Master thesis, 2021)Multiple myeloma (MM) is an incurable cancer arising in the antibody-producing plasma cells that are located in the bone marrow. The malignant cells disturb the balance between bone forming and bone degrading cells, leading ... -
Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
(Journal article; Peer reviewed, 2015)Background: The chemokine CCL20 and its receptor CCR6 are putative drug targets in inflammatory bowel disease, and CCL20 is a novel IBD predilection gene. Previous findings on the CCL20 response in these diseases are ... -
Expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma
(Journal article; Peer reviewed, 2017)The aim of the study was to investigate the expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma (CCRCC). We retrospectively reviewed the medical records and re-evaluated histopathological ... -
Expression of estrogen receptor-α and survival in advanced-stage non-small cell lung cancer
(Journal article; Peer reviewed, 2018)Background/Aim: The favorable prognosis of women with non-small-cell lung cancer (NSCLC) compared to men might be explained by sex hormone-related mechanisms. We investigated whether this observation could be explained by ... -
Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients
(Journal article; Peer reviewed, 2017)Background: Several studies have identified L1 cell adhesion molecule (L1CAM) as a strong prognostic marker in endometrial cancer. To further underline the clinical usefulness of this biomarker, we investigated L1CAM as ... -
Expression of Multidrug Reisistance Protein ABCB1 and Drug Sensitivity in Carfilzomib Resistant Myeloma Cell Lines
(Master thesis, 2021)Myelomatose/beinmargskreft er den andre mest vanlige hematologiske sykdommen i verden, og er en krefttype som kommer av ukontrollert vekst av plasmaceller i beinmargen. Det finnes foreløpig ingen kurerende behandling, ... -
Expression of PPARγ in inflammatory bowel disease: a role in regulating colonic inflammation
(Master thesis, 2017)Background: Inflammatory bowel disease (IBD) is a collective term for the two entities, ulcerative colitis (UC) and Crohn’s disease (CD). They are both characterized by a relapsing inflammation causing destruction of the ... -
Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells
(Journal article, 2017)Gastric cancer is an important disease due to its high mortality. Despite the decline in frequency, most cases are discovered late in its course, and most of the cancer patients die within a few years of diagnosis. In ... -
The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
(Peer reviewed; Journal article, 2020)The long non-coding RNA NEAT1 locus is transcribed into two overlapping isoforms, NEAT1_1 and NEAT1_2, of which the latter is essential for the assembly of nuclear paraspeckles. NEAT1 is abnormally expressed in a wide ... -
Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2
(Journal article; Peer reviewed, 2013)Anti-microbial peptides might influence the pathogenesis and course of inflammatory bowel disease (IBD). We sought to clarify the role of the anti-microbial glycoprotein lipocalin 2 (LCN2) in the colon by determining its ... -
Expression of Transforming growth factor beta in Breast Cancer Subtypes
(Master thesis, 2017)Background: Normally, transforming growth factor beta (TGF-b) functions as a tumorsuppressor. But, during carcinogenesis, malignant cells become insensitive to TGF-b´s growth inhibitory abilities, and the traits of TGF-b ... -
Expression of β-Catenin, E-Cadherin, and α-Smooth Muscle Actin in Basal Cell Carcinoma Before Photodynamic Therapy in Non-recurrent and Recurrent Tumors: Exploring the Ability of Predicting Photodynamic Therapy outcome
(Peer reviewed; Journal article, 2023)Photodynamic therapy (PDT) is an effective and cosmetically beneficial treatment of low-risk basal cell carcinomas (BCCs). To optimize PDT response, it is important to correctly select tumors. We sought to find markers ... -
External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis
(Peer reviewed; Journal article, 2020)Background Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk during pregnancy is required to plan management. Although there are many published ...