Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1067-1086 of 3426
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European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia
(Peer reviewed; Journal article, 2020)The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy. Another goal is achieving a stable deep ... -
Evaluating complex interventions in End of Life Care: the MORECare Statement on good practice generated by a synthesis of transparent expert consultations and systematic reviews
(Journal article; Peer reviewed, 2013)Background Despite being a core business of medicine, end of life care (EoLC) is neglected. It is hampered by research that is difficult to conduct with no common standards. We aimed to develop evidence-based guidance on ... -
Evaluation of a surgical task sharing training programme's logbook system in Sierra Leone
(Journal article; Peer reviewed, 2019)Background Personal logbooks are universally applied for monitoring and evaluation of surgical trainees; however, the quality and accuracy of such logbooks in low income countries (LICs) are poorly examined. Logbooks ... -
Evaluation of a surgical trainee logbook system in Sierra Leone
(Master thesis, 2017)Background Task-sharing is an increasingly used tool to improve surgical capacity in low-income countries. Within task-sharing training programs surgical logbooks are commonly applied for monitoring and evaluation of the ... -
Evaluation of hypoglycaemia with non-invasive sensors in people with type 1 diabetes and impaired awareness of hypoglycaemia
(Journal article; Peer reviewed, 2018)People with type 1 diabetes and impaired awareness of hypoglycaemia (IAH) are prone to severe hypoglycaemia. Previous attempts to develop non-invasive hypoglycaemia alarm systems have shown promising results, but it is not ... -
Evaluation of metabolomic changes during neoadjuvant chemotherapy combined with bevacizumab in breast cancer using MR spectroscopy
(Journal article; Peer reviewed, 2017)Introduction Metabolomics investigates biochemical processes directly, potentially complementing transcriptomics and proteomics in providing insight into treatment outcome. Objectives This study aimed to use ... -
Evaluation of Neoadjuvant Chemotherapy in Patients with Resectable Gastric Adenocarcinoma in Central Norway 2007 – 2016
(Doctoral theses at NTNU;2024:12, Doctoral thesis, 2024)This thesis presents three retrospective, population-based, observational studies on patients diagnosed with upfront resectable gastric adenocarcinoma and receiving neoadjuvant chemotherapy (NAC) in Central Norway during ... -
Evaluation of photochemical internalization of Caelyx in cholangiocarcinoma cell lines
(Master thesis, 2019)Gallegangskreft er en type kreft med svært dårlig prognose på grunn av dens aggressivitet og motstand mot forskjellige behandlinger. I dag er kirurgi den eneste kuren, men majoriteten av pasienter diagnostiseres for sent ... -
Evaluation of Real-Time PCR for rapid phenotypic susceptibility testing of Escherichia coli to gentamicin
(Master thesis, 2021)Slappe strategier for infeksjonskontroll og høyt forbruk av antimikrobielle stoffer i noen land gir god grobunn for resistente bakterier, og med en svært sammenkoblet verden kan mikrober spre seg fort. Blodstrømsinfeksjoner ... -
Evaluation of the medical student research programme inNorwegian medical schools: A survey of students and supervisors
(Journal article; Peer reviewed, 2009) -
Evaluation of the proliferation markers Ki-67/MIB-1, mitosin, survivin, pHH3, and DNA topoisomerase II alpha in human anaplastic astrocytomas - an immunohistochemical study
(Journal article; Peer reviewed, 2011)Background Histological malignancy grading of astrocytomas can be challenging despite criteria given by the World Health Organisation (WHO). Grading is fundamental for optimal prognostication and treatment, and additional ... -
Evaluation of the role of physical activity levels on the release of appetite-related hormones after preloads with a different energy content
(Master thesis, 2014)Background:Previous research has shown that regular exercisers are able to adjust their energy intake after preloads of different energy content, while inactive individuals are not. However, the mechanisms responsible ... -
Evaluation of treatment with two weeks of doxycycline on macrolide-resistant strains of Mycoplasma genitalium: a retrospective observational study
(Peer reviewed; Journal article, 2021)Background Increasing macrolide resistance makes treatment of Mycoplasma genitalium infections challenging. The second-line treatment is moxifloxacin, an antibiotic drug best avoided due to the potential of severe side ... -
Evaluation of Variants of Uncertain Significance in MLH1 and MSH6 genes of the Mismatch Repair System
(Master thesis, 2021)Tykktarmskreft (CRC) er en av de vanligste kreftformene både over hele verden og i Norge. Mutasjoner med høy penetrasjon fører til predisponering for kolorektal kreft, som omfatter opptil 5% av alle tilfeller av kolorektal ... -
Evalueringsrapport kompetansehevingsprosjektet 'STYRK-DIA - Bedre diabetesbehandling ved helse- og velferdssentrene i Helse Midt-Norge'
(Research report, 2017)Bakgrunn: Samhandlingsreformen forventer mer aktiv samhandling om pasientbehandling mellom spesialist- og kommunehelsetjenesten. Spesialisthelsetjenesten har veilederansvar og kommunene har ansvar for å sette i verk tiltak ... -
Evidence of impaired bone quality in men with type 1 diabetes: A cross-sectional study
(Peer reviewed; Journal article, 2021)Objective Type 1 diabetes (T1D) is associated with substantial fracture risk. Bone mineral density (BMD) is, however, only modestly reduced, suggesting impaired bone microarchitecture and/or bone material properties. Yet, ... -
Evolution and risk factors of anal incontinence during the first 6 years after first delivery: a prospective cohort study
(Journal article; Peer reviewed, 2020) -
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy
(Journal article; Peer reviewed, 2017)Background: Robust biomarkers that identify prostate cancer patients with high risk of recurrence will improve personalised cancer care. In this study, we investigated whether tissue metabolites detectable by high-resolution ... -
Examination of different APIM-variants and APIM's role in TRF2 protection of the telomere ends
(Master thesis, 2013)Most chemotherapeutic drugs induce DNA damage to the cells. However, the toxicity of DNA damaging drugs can be reduced by DNA repair mechanisms, and the cancer cells can survive despite the damage. Therefore, by targeting ... -
Examinations of the functionality of APIM in TRF2 and the importance for telomere stability
(Master thesis, 2014)Maintaining genome integrity is crucial for life, and therefore, complex control and repair mechanisms have evolved. Because cells are especially susceptible to damage during replication, many DNA repair pathways are coupled ...