Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 1049-1068 av 3590
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Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
(Journal article; Peer reviewed, 2006)Immune responses are initiated when molecules of microbial origin are sensed by the Toll‐like receptors (TLRs). We now report the identification of essential molecular components for the trafficking of the lipopolysaccharide ... -
Endogenous ligands secreted by multiple myeloma cell lines activate TLRs 7, 8, and 9
(Master thesis, 2020) -
Endometrial cancer: diagnostic accuracy of preoperative imaging and oncologic outcome and treatment complications after implementation of a sentinel lymph node algorithm
(Doctoral theses at NTNU;2023:345, Doctoral thesis, 2023)SAMMENDRAG PÅ NORSK Livmorkreft er den vanligste gynekologiske kreftformen i den vestlige verden, og i Norge rammes drøyt 800 kvinner hvert år. Omtrent 80 % av pasientene diagnostiseres på et tidlig stadium med god prognose. ... -
Endonuclease v regulates atherosclerosis through c-c motif chemokine ligand 2-mediated monocyte infiltration
(Journal article; Peer reviewed, 2021)Background In cardiovascular diseases, atherosclerotic disorder are the most frequent and important with respect to morbidity and mortality. Inflammation mediated by immune cells is central in all parts of the atherosclerotic ... -
Endotoxin removal in septic shock with the Alteco LPS Adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial - the Asset Study
(Peer reviewed; Journal article, 2020)Purpose: Lipopolysaccharides (LPS) are presumed to contribute to the inflammatory response in sepsis. We investigated if extracorporeal Alteco LPS Adsorber for LPS removal in early gram-negative septic shock was feasible ... -
Endpoints in clinical trials in cancer cachexia: where to start?
(Journal article; Peer reviewed, 2018)Purpose of review The lack of agreement and knowledge of optimal endpoints in cachexia trials have impeded progress in finding interventions counteracting the devastating effects cancer cachexia has on morbidity and ... -
Endringer i bruk av antiepileptika i Skandinavia og Norge (2006-2017/18) med fokus på barn og unge
(Master thesis, 2020)Bakgrunn: I dag finnes det om lag 27 ulike antiepileptika under ATC-koden N03A på markedet i Skandinavia. Bruk av disse hos barn og unge er lite undersøkt. Skandinaviske reseptregistre kan brukes til å kartlegge legemiddelbruk ... -
Energimetabolisme i skjelettmuskelceller fra smertepasienter : myokiner, smerteopplevelse og effekt av trimetylamin N-oksid
(Master thesis, 2016)Background: Dysfunctional energy metabolism in skeletal muscle is associated with obesity, metabolic syndrome, type 2 diabetes (T2DM) and cardiovascular diseases (CVD). Detrimental changes in energy metabolism are result ... -
Enhanced efficacy of bleomycin in bladder cancer cells by photochemical internalization
(Journal article; Peer reviewed, 2014)Bleomycin is a cytotoxic chemotherapeutic agent widely used in cancer treatment. However, its efficacy in different cancers is low, possibly due to limited cellular internalization. In this study, a novel approach known ... -
Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation
(Journal article, 2013)We explored the gene expression in colonic biopsies of active and inactive inflammatory bowel disease (IBD), in an extensive material of ulcerative colitis (UC) and Crohn`s disease (CD). The chemokine CXCL10 and its receptor ... -
Enhanced identification of significant regulators of gene expression
(Peer reviewed; Journal article, 2020)Background Diseases like cancer will lead to changes in gene expression, and it is relevant to identify key regulatory genes that can be linked directly to these changes. This can be done by computing a Regulatory Impact ... -
Enhancement of Insulin Absorption by Local Manipulation of the Site of Injection
(Master thesis, 2019)Bakgrunn: Trege og uforutsigbare absorpsjonsprofiler av subkutant injiserte måltidsinsuliner er ansett som en stor utfordring i behandlingen av diabetes type 1, og resulterer ofte i en forsinket topp og en langvarig ... -
Enhancing knowledge and coordination in obesity treatment: a case study of an innovative educational program
(Journal article; Peer reviewed, 2019)Currently, there is a lack of knowledge, organisation and structure in modern health care systems to counter the global trend of obesity, which has become a major risk factor for noncommunicable diseases. Obesity increases ... -
Enhancing Palliative Care in Primary Healthcare for Patients with Cancer: Integrating Advance Care Planning to Support Home-Based Care at the End-of-Life
(Doctoral theses at NTNU;2024:295, Doctoral thesis, 2024)According to the World Health Organization (WHO), cancer is a significant global health issue and one of the leading causes of death worldwide. An increasing number of cancer patients, live longer with modern oncology ... -
An ensemble framework for identifying essential proteins
(Peer reviewed; Journal article, 2016)Many centrality measures have been proposed to mine and characterize the correlations between network topological properties and protein essentiality. However, most of them show limited prediction accuracy,and the number ... -
Entorhinal fast-spiking speed cells project to the hippocampus
(Journal article; Peer reviewed, 2018)The mammalian positioning system contains a variety of functionally specialized cells in the medial entorhinal cortex (MEC) and the hippocampus. In order for cells in these systems to dynamically update representations in ... -
Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway
(Journal article; Peer reviewed, 2021) -
Epidemiological and Clinical Insights into the Enterovirus D68 Upsurge in Europe 2021–2022 and Emergence of Novel B3-Derived Lineages, ENPEN Multicentre Study
(Peer reviewed; Journal article, 2024)Enterovirus D68 (EV-D68) infections are associated with severe respiratory disease and acute flaccid myelitis (AFM). The European Non-Polio Enterovirus Network (ENPEN) aimed to investigate the epidemiological and genetic ... -
Epidemiology and outcome of Staphylococcus aureusbloodstream infection and sepsis in a Norwegian county 1996–2011: an observational study
(Journal article; Peer reviewed, 2015)Background: Staphylococcus aureus is one of the most common and lethal causes of bloodstream infection and the incidence is increasing. We carried out a prospective observational study of patients with Staphylococcus ... -
Epidurals during normal labour and birth — Midwives’ attitudes and experiences
(Peer reviewed; Journal article, 2020)Background Midwives have their own beliefs and values regarding pain during childbirth. Their preferences concerning labour pain management may influence women’s choices. Aim To gain a deeper understanding of midwives’ ...