Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1047-1066 of 3430
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Establishing a real-time PCR method for analysis of stx2 expression
(Master thesis, 2013)STEC (Shiga toxin-producing E.coli) are important human pathogens, which can potentially cause hemolytic uremic syndrome (HUS). An important predictor of serious disease is the production of the variant Shiga toxin 2 (Stx2). ... -
Establishing Methodology and Best Practices for Metagenomic and Metatranscriptomic Study of the Human Gut Microbiome
(Master thesis, 2022)Due to its fundamental impact on overall health, the gut microbiome has emerged as one of the most popular research subjects over the last decade. It is believed that there are associations between gut microbial perturbation ... -
Establishing Serum Reference Ranges for Antihypertensive Drugs
(Peer reviewed; Journal article, 2020)Background: Therapeutic drug monitoring (TDM) involves the measurement of serum drug concentrations to optimize pharmacotherapy. Traditionally, blood pressure measurements alone, and not TDM, have been used to evaluate ... -
Establishing the representativeness of available surface water scenarios for plant protection products in environmental risk assessment Opinion of the Panel on Plant protection Products of the Norwegian Scientific Committee for Food and Environment (VKM)in Norway -
(Peer reviewed; Journal article, 2021) -
Establishing tools to study the involvement of Keap1 in inflammatory signaling upon infection with M. avium
(Master thesis, 2015)Mycobacterium avium is a non-tuberculous mycobacteria that causes opportunistic infections in immunocompromised individuals such as AIDS patients. The pathogen is receiving more attention due to increasing resistance ... -
Establishment of a patient-derived xenograft model of colorectal cancer in CIEA NOG mice and exploring smartfish liquid diet as a source of omega-3 fatty acids
(Peer reviewed; Journal article, 2021)Cancer patient-derived xenografts (PDXs) better preserve tumor characteristics and microenvironment than traditional cancer cell line derived xenografts and are becoming a valuable model in translational cancer research ... -
Establishment of an image analysis and acquisition platform used to test host-directed therapy in Mycobacterium avium infection
(Master thesis, 2021)Bakgrunn: Mycobacterium avium er en non-tuberkuløs mykobakterie (NTM), som er nært beslektet med Mycobacterium tuberculosis, som gir NTM lungesykdom. NTM infeksjon er vanskelig å behandle og krever en behandling med flere ... -
Establishment of an in vivo rat model for chronic musculoskeletal implant infection
(Peer reviewed; Journal article, 2020)Background The aim of the study was to establish an experimental chronic musculoskeletal infection model in vivo characterized by (a) a small bacterial inoculum, (b) no general or local signs of infection, (c) several ... -
Establishment of methods for high throughput screening of nanoparticle toxicity in mammalian cells
(Master thesis, 2015)The use of nanomaterials is getting more extensive, both within the industrial and the medical field. The production and implementation of nanomaterials into consumer market is rapid and at such a rate that they are preceding ... -
Establishment of Multiple Myeloma Cell lines with Hepatocyte growth factor (HGF) overexpression and knockdown
(Master thesis, 2013)Multiple myeloma is the malignancy of plasma cells which causes 0.9 % of all cancer related deaths. These malignant plasma cells acquire chromosomal abnormalities and complex genetic instability. Hepatocyte growth factor ... -
Establishment of Tissue Microarray for Molecular – Genetic Subclassification of Colorectal Cancer
(Master thesis, 2011)In 30-70% of colorectal cancers colonization of the liver leads to high mortality. Most liver metastases are unresectable and recurrence level after surgery is high (50%). Identification of patients at high risk to develop ... -
Estimated cardiorespiratory fitness in relation to overall, breast and prostate cancer incidence: The Norwegian HUNT Study
(Peer reviewed; Journal article, 2022)Purpose To investigate the relationships between the estimated cardiorespiratory fitness (eCRF) and the incidence of overall, breast, and prostate cancer in a large prospective cohort study. Methods We included ... -
Estimated Kidney Tubular Secretion and Kidney, Cardiovascular, and Mortality Outcomes in CKD: The Systolic Blood Pressure Intervention Trial
(Peer reviewed; Journal article, 2022)Rational & Objective Many drugs, metabolites, and toxins are cleared by the kidneys via tubular secretion. Whether novel endogenous measures of tubular secretion provide information about kidney, cardiovascular, and ... -
An Estimation Model for Cardiorespiratory Fitness in Adults with Rheumatoid Arthritis
(Peer reviewed; Journal article, 2020)Purpose Cardiopulmonary exercise testing of peak oxygen uptake (V˙O2peak) is the gold standard to measure cardiorespiratory fitness (CRF). For resource-intensive evaluation, equations estimating CRF (eCRF) may be used. ... -
Estimation of fetal weight in pregnancies past term
(Journal article; Peer reviewed, 2016)Introduction The aim of the study was to investigate the accuracy of estimating fetal weight with ultrasound in pregnancies past term, using the eSnurra algorithm. Material and methods In all, 419 women with pregnancy ... -
Et apatisk barn med hallusinasjoner
(Peer reviewed; Journal article, 2021) -
EtG and EtS in autopsy blood samples with and without putrefaction using UPLC-MS-MS
(Journal article; Peer reviewed, 2017)Analytical challenges related to postmortem specimens are well known. The degree of putrefaction of the corpse will influence the quality of the blood samples, and both the efficiency of sample preparation and the subsequent ... -
EtG/EtS in Serum by UHPLC-MS-MS in Suspected Sexual Assault Cases
(Journal article; Peer reviewed, 2017)A method including semi-automated extraction of ethyl glucuronide (EtG) and ethyl sulfate (EtS) from serum followed by ultra-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS-MS) has been developed and ... -
Ethical challenges and reflection. Norwegian bachelor students’ experiences during clinical placement in Sub-Saharan Africa
(Peer reviewed; Journal article, 2023)Background Clinical placements in nursing abroad are important for awareness and ethical reflections for Norwegian bachelor students in nursing. The purpose of this study was to gain a deeper understanding of Norwegian ... -
Ethical questions related to the development of telemedicine
(Journal article, 2003)