Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 2649-2668 of 3434
-
Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification
(Journal article; Peer reviewed, 2019)The wobble hypothesis was proposed to explain the presence of fewer tRNAs than possible codons. The wobble nucleoside position in the anticodon stem-loop undergoes a number of modifications that help maintain the efficiency ... -
Recommendations for the FAIRification of genomic track metadata
(Journal article; Peer reviewed, 2021) -
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation
(Journal article; Peer reviewed, 2015)Chronic inflammation of the arterial wall is a key element in the development of atherosclerosis, and cholesterol crystals (CC) that accumulate in plaques are associated with initiation and progression of the disease. We ... -
Record linkage as a vital key player for the COVID-19 syndemic – The call for legal harmonization to overcome research challenges
(Peer reviewed; Journal article, 2023)The initial public health response to the COVID-19 pandemic aimed to prevent exponential dissemination and circumvent drastic collapses of healthcare systems [1]. Containment measures and required isolation promoted sedentary ... -
Recovery trajectories in common musculoskeletal complaints by diagnosis contra prognostic phenotypes
(Peer reviewed; Journal article, 2021)Background There are large variations in symptoms and prognostic factors among patients sharing the same musculoskeletal (MSK) diagnosis, making traditional diagnostic labelling not very helpful in informing treatment ... -
Rectal cancer surgery: Prognostic Factors Related to Treatment
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:284, Doctoral thesis, 2012)Background Towards the end of the 80-ties, 28 % of the rectal cancer patients treated for cure developed local recurrence, and only 55 % survived five years. Since 1993, intensified focus on the rectal cancer patients has ... -
Rectal cancer treatment: Considerations on early stages, risk prediction and influence of age
(Doctoral thesis at NTNU;2016:86, Doctoral thesis, 2016)Målsetningen med studiene i denne avhandlingen var å bidra til å bedre prognose ved behandling av rektumcancer, med spesielt fokus på pasienter over 75 år. Prognosen ved kolorektal cancer (CRC) i Norge har de siste 20-30 ... -
Recurrent malignant ventricular arrhythmias and paresthesia—a mystery revealed as aconitine poisoning: a case report
(Peer reviewed; Journal article, 2023)Background: We report a case of a clinical challenge lasting for 12 months, with severe and unresolved clinical features involving several medical disciplines. Case presentation: A 53-year-old Caucasian male, who had been ... -
Red versus blue light illumination in hexyl 5-aminolevulinate photodynamic therapy: the influence of light color and irradiance on the treatment outcome in vitro
(Journal article; Peer reviewed, 2014)Abstract. Hexyl 5-aminolevulinate (HAL) is a lipophilic derivative of 5-aminolevulinate, a key intermediate in biosynthesis of the photosensitizer protoporphyrin IX (PpIX). The photodynamic efficacy and cell death mode ... -
Reduced cardiorespiratory fitness is a mediator of excess all-cause mortality in rheumatoid arthritis: The Trøndelag Health Study
(Peer reviewed; Journal article, 2021)Objectives Investigate if low cardiorespiratory fitness (CRF) was associated with and acted as a mediator of excess all-cause mortality rate in persons suffering from rheumatoid arthritis (RA) compared with the general ... -
Reduced hippocampal subfield volumes and memory function in school-aged children born preterm with very low birthweight (VLBW)
(Journal article; Peer reviewed, 2019)Background The hippocampus, an essential structure for learning and memory, has a reduced volume in preterm born (gestational age < 37 weeks) individuals with very low birth weight (VLBW: birth weight < 1500 g), which ... -
Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
(Journal article, 2017)Objectives. The inflammatory response to on-pump cardiac surgery is well known. Systemic inflammatory response syndrome after transcatheter valve implantation (TAVI) has been reported. The objective of this study was to ... -
Reduced LDL-Cholesterol and Reduced Total Cholesterol as Potential Indicators of Early Cancer in Male Treatment-Naïve Cancer Patients With Pre-cachexia and Cachexia
(Peer reviewed; Journal article, 2020)Cancer cachexia is characterized by the impairment of glucose and lipid homeostasis, the acceleration of processes promoting the mobilization of energy-rich compounds (e.g., insulin resistance, gluconeogenesis, and lipolysis) ... -
Reduced Long-Term Relative Survival in Females and Younger Adults Undergoing Cardiac Surgery: A Prospective Cohort Study
(Journal article; Peer reviewed, 2016)Objectives To assess long-term survival and mortality in adult cardiac surgery patients. Methods 8,564 consecutive patients undergoing cardiac surgery in Trondheim, Norway from 2000 until censoring 31.12.2014 were ... -
Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation
(Journal article; Peer reviewed, 2017)Background In the randomized, controlled study Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT), maternal probiotic supplementation reduced the incidence of atopic dermatitis (AD) in the ... -
Reduced white matter fractional anisotropy mediates cortical thickening in adults born preterm with very low birthweight.
(Journal article; Peer reviewed, 2018)Development of the cerebral cortex may be affected by aberrant white matter development. Preterm birth with very low birth weight (VLBW) has been associated with reduced fractional anisotropy of white matter and changes ... -
‘Reduced’ HUNT model outperforms NLST and NELSON study criteria in predicting lung cancer in the Danish screening trial
(Journal article; Peer reviewed, 2019)Hypothesis We hypothesise that the validated HUNT Lung Cancer Risk Model would perform better than the NLST (USA) and the NELSON (Dutch‐Belgian) criteria in the Danish Lung Cancer Screening Trial (DLCST). Methods The ... -
Reducing prostate biopsies and magnetic resonance imaging with prostate cancer risk stratification
(Journal article; Peer reviewed, 2022) -
Reference limits for chromogranin A, CYFRA 21-1, CA 125, CA 19-9 and carcinoembryonic antigen in patients with chronic kidney disease
(Journal article; Peer reviewed, 2017)Background Patients with chronic kidney disease (CKD) may have increased plasma concentrations of some tumor markers even when no cancer is present. Previous studies have indicated that plasma concentrations of chromogranin ... -
Reference material for Hammersmith Infant Neurological Examination scores based on healthy, term infants aged 3 to 7 months
(Journal article; Peer reviewed, 2022)Objective To provide a valid, continuous reference interval, including a 10 th percentile cut-off, for Hammersmith Infant Neurological Examination (HINE) scores based on 3-7 months old term infants with weight appropriate ...