Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1549-1568 of 3554
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Hypertensive nephrosclerosis: wider kidney biopsy indications may be needed to improve diagnostics
(Peer reviewed; Journal article, 2020)Background. Hypertensive nephrosclerosis is the presumed underlying cause in many end-stage kidney disease (ESKD) patients, but the diagnosis is disputed and based on clinical criteria with low diagnostic accuracy. Objective. ... -
Hypertensive pregnancy disorders increase the risk of maternal cardiovascular disease after adjustment for cardiovascular risk factors
(Peer reviewed; Journal article, 2019)Background and aim Hypertensive pregnancy disorders are associated with subsequent cardiovascular disease (CVD), but the extent to which this association is explained by shared risk factors is unknown. We aimed to evaluate ... -
Hypoglycemia in adults with Type 1 Diabetes Mellitus: Investigating symptoms and awareness of hypoglycemia and the association between impaired awareness of hypoglycemia, autonomic neuropathy and cognition
(Doctoral theses at NTNU;2016:317, Doctoral thesis, 2016)Hypoglycemia is still the main limitation for the management of Type 1 diabetes mellitus (T1DM). If it were not for hypoglycemia, treatment of T1DM would be easy. Subjects with T1DM have impaired defense mechanisms against ... -
Hypoxia promotes IL-32 expression in myeloma cells, and high expression is associated with poor survival and bone loss
(Journal article; Peer reviewed, 2017)Multiple myeloma (MM) is a hematologic cancer characterized by expansion of malignant plasma cells in the bone marrow. Most patients develop an osteolytic bone disease, largely caused by increased osteoclastogenesis. The ... -
Hysterektomi i Norge 2008–18
(Peer reviewed; Journal article, 2020)Background: Hysterectomy is a common gynaecological procedure. No Norwegian guidelines for the choice of hysterectomy surgical method exist, but international guidelines recommend minimally invasive surgery. The objective ... -
Hysterektomi ved St. Olavs hospital 1989-2014
(Journal article; Peer reviewed, 2017)BAKGRUNN Hysterektomi er en av de vanligste gynekologiske operasjonene. Operasjonsmetodene har endret seg de siste decenniene. Nye utredningsmuligheter og alternative behandlingsmetoder har kommet til. Hensikten med denne ... -
Hysterotomy level at cesarean section and occurrence of large scar defects: a randomized single-blind trial
(Peer reviewed; Journal article, 2019)Objective To study the association between the level of Cesarean hysterotomy and the presence of large uterine scar defects 6–9 months after delivery. Methods This was a two-center, randomized, single-blind trial of ... -
Høy forekomst av Mycoplasma genitalium hos kvinner under 25 år: Prevalensundersøkelse av M. genitalium i pasientprøver som testes for C. trachomatis
(Master thesis, 2012)Formål med studien: Å kartlegge forekomsten av M. genitalium infeksjoner blant en uselektert gruppe pasienter som skal testes for C. trachomatis. Forekomsten av mørketall for M. genitalium ved diagnostikk av C. trachomatis ... -
Høyt nivå av tungmetaller i krabbe
(Journal article; Peer reviewed, 2022) -
I jordmors hender - En kvalitativ studie om kvinners opplevelse av å føde på en jordmorstyrt enhet
(Master thesis, 2022)Bakgrunnen for studien er at det sees en økende medikalisering innen den moderne fødselsomsorgen. Dette utgjør en risiko for økt forekomst av intervensjoner i fødselsforløpet, noe som kan ha påvirkning på hvilken opplevelse ... -
I jordmors hender- En kvalitativ studie om kvinners opplevelse av å føde på en jordmorstyrt enhet
(Master thesis, 2022)Bakgrunnen for studien er at det sees en økende medikalisering innen den moderne fødselsomsorgen. Dette utgjør en risiko for økt forekomst av intervensjoner i fødselsforløpet, noe som kan ha påvirkning på hvilken opplevelse ... -
Icotinib is an active treatment of non-small-cell lung cancer: A retrospective study
(Journal article; Peer reviewed, 2014)Background Icotinib hydrochloride is a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with preclinical and clinical activity in non-small cell lung cancer (NSCLC). This retrospective ... -
Identification and Tracking of Antiviral Drug Combinations
(Peer reviewed; Journal article, 2020)Combination therapies have become a standard for the treatment for HIV and hepatitis C virus (HCV) infections. They are advantageous over monotherapies due to better efficacy, reduced toxicity, as well as the ability to ... -
Identification of a regulatory pathway governing TRAF1 via an arthritis-associated non-coding variant
(Peer reviewed; Journal article, 2023)TRAF1/C5 was among the first loci shown to confer risk for inflammatory arthritis in the absence of an associated coding variant, but its genetic mechanism remains undefined. Using Immunochip data from 3,939 patients with ... -
Identification of genes affecting alginate biosynthesis in Pseudomonas fluorescens by screening a transposon insertion library.
(Journal article; Peer reviewed, 2017)BACKGROUND: Polysaccharides often are necessary components of bacterial biofilms and capsules. Production of these biopolymers constitutes a drain on key components in the central carbon metabolism, but so far little is ... -
Identification of genetic polymorphisms modulating nausea and vomiting in two series of opioid-treated cancer patients
(Peer reviewed; Journal article, 2020)Nausea and vomiting are often associated with opioid analgesia in cancer patients; however, only a subset of patients develop such side effects. Here, we tested the hypothesis that the occurrence of nausea and vomiting is ... -
Identification of Metabolites from 2D 1H-13C HSQC NMR using Peak Correlation Plots
(Journal article; Peer reviewed, 2014)Background Identification of individual components in complex mixtures is an important and sometimes daunting task in several research areas like metabolomics and natural product studies. NMR spectroscopy is an excellent ... -
Identification of metastasis-associated microRNAs in serum from rectal cancer patients
(Peer reviewed; Journal article, 2017)MicroRNAs (miRNAs) are promising prognostic and diagnostic biomarkers due to their high stability in blood. Here we investigate the expression of miRNAs and other noncoding (nc) RNAs in serum of rectal cancer patients. ... -
Identification of MicroRNA Expression in Gastrin Stimulated Adenocarcinoma Cells
(Master thesis, 2011)The Gastrin System Biology group studies the molecular responses to gastrin using cell line model systems. Recently microRNAs (miRNAs) have been acknowledged as essential participants in the regulation of gene expression, ...