Blar i Institutt for klinisk og molekylær medisin på tittel
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Exploring responses of type I and type III interferons in human macrophages
(Master thesis, 2021)Interferons are antiviral cytokines induced during viral infection. Type I and III IFNs are thought to share some of the same transcriptional outputs, yet some biological responses are distinct. IFN-λ receptor (IFNLR1) ... -
Exploring the Crosstalk Between RIG-I-mediated Signalling and β-catenin
(Master thesis, 2011)Hepatocellular carcinoma (HCC) is the most common type of liver cancer and among the leading causes of cancer related death worldwide. Hepatocarcinogenesis has been attributed to chronic viral infection and alterations in ... -
Exploring the diagnostic potential of adding T2 dependence in diffusion-weighted MR imaging of the prostate
(Peer reviewed; Journal article, 2021)Background: Magnetic resonance imaging (MRI) is essential in the detection and staging of prostate cancer. However, improved tools to distinguish between low-risk and high-risk cancer are needed in order to select the ... -
Exploring the fungal microbiome in breast cancer patients
(Master thesis, 2021)The role of the Fungal Microbiome in the human body has been gradually revealed. Its presence in the gut, although scarce in comparison to bacteria, is now associated with several physiologic functions such as immune ... -
Exploring the hepatitis C virus encoded protease NS3/4A in relation to Autophagy
(Master thesis, 2011)Autophagy is an evolutionarily conserved intracellular bulk degradation system essential for the cell homeostasis. In addition, autophagy is emerging as a central component in viral host defense. Many pathogens have evolved ... -
Exploring the relationship between bone density and severity of distal radius fragility fracture in women
(Journal article; Peer reviewed, 2014)Background Bone mineral density (BMD) has been shown to be a consistent and independent risk factor for distal radius fracture. Inconsistent data have been reported on the association between BMD and severity of distal ... -
Exploring the role of IKKε during hepatitis C virus infection with focus on lipid accumulation
(Master thesis, 2020)Hepatitis C virus (HCV) targets the hepatocytes in the liver. HCV develops a chronic infection in 85% of infected patients which develops over decades and have different outcomes, for example hepatic steatosis (accumulation ... -
Exploring the role of the immunoglobulin-like receptor SLAMF1 in infection with human metapneumovirus
(Master thesis, 2021)Humant metapneumovirus (HMPV) er en ledende årsak til nedre luftveisinfeksjon. Generelt finnes det lite informasjon om hvordan HMPV entrer (infiserer), etablerer replikasjon og induserer immunresponser. Nylige funn fra en ... -
Exploring the role of TLR8 as a sensor in bacterial infections
(Doctoral theses at NTNU;2019:382, Doctoral thesis, 2019) -
Exploring the viability of measuring zinc and prostate-specific antigen in urine as a diagnostic tool for prostate cancer
(Master thesis, 2021)Bakgrunn: Nåværende metoder for å diagnostisere prostatakreft benytter seg av inngripende biopsier, som kan føre til komplikasjoner som infeksjon og død. Ikke-inngripende metoder benytter seg av PSA målinger, som ofte er ... -
Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice
(Journal article; Peer reviewed, 2015)Type 1 diabetes mellitus (T1DM) is an autoimmune destruction of insulin producing pancreatic beta-cells due to a genetic predisposition and can be triggered by environmental factors. We have previously shown that bisphenol ... -
Express Team-Based Learning (eTBL): A Time-Efficient TBL Approach in Neuroradiology
(Peer reviewed; Journal article, 2019)Rationale and Objectives Team-based learning (TBL) is a student-centred, teacher-directed instructional method that promotes active learning. The application phase of TBL stimulates group discussion and critical thinking, ... -
Expression and clinical significance of the proliferation marker minichromosome maintenance protein 2 (Mcm2) in diffuse astrocytomas WHO grade II
(Journal article; Peer reviewed, 2013)Background The WHO classification system for astrocytomas is not considered optimal, mainly because of the subjective assessment of the histopathological features. Few prognostic variables have been found that stratify ... -
Expression and clinical value of EGFR in human meningiomas
(Journal article; Peer reviewed, 2017)Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal ... -
Expression and function of FSTL5 in multiple myeloma cells
(Master thesis, 2021)Multiple myeloma (MM) is an incurable cancer arising in the antibody-producing plasma cells that are located in the bone marrow. The malignant cells disturb the balance between bone forming and bone degrading cells, leading ... -
Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
(Journal article; Peer reviewed, 2015)Background: The chemokine CCL20 and its receptor CCR6 are putative drug targets in inflammatory bowel disease, and CCL20 is a novel IBD predilection gene. Previous findings on the CCL20 response in these diseases are ... -
Expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma
(Journal article; Peer reviewed, 2017)The aim of the study was to investigate the expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma (CCRCC). We retrospectively reviewed the medical records and re-evaluated histopathological ... -
Expression of estrogen receptor-α and survival in advanced-stage non-small cell lung cancer
(Journal article; Peer reviewed, 2018)Background/Aim: The favorable prognosis of women with non-small-cell lung cancer (NSCLC) compared to men might be explained by sex hormone-related mechanisms. We investigated whether this observation could be explained by ... -
Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients
(Journal article; Peer reviewed, 2017)Background: Several studies have identified L1 cell adhesion molecule (L1CAM) as a strong prognostic marker in endometrial cancer. To further underline the clinical usefulness of this biomarker, we investigated L1CAM as ... -
Expression of Multidrug Reisistance Protein ABCB1 and Drug Sensitivity in Carfilzomib Resistant Myeloma Cell Lines
(Master thesis, 2021)Myelomatose/beinmargskreft er den andre mest vanlige hematologiske sykdommen i verden, og er en krefttype som kommer av ukontrollert vekst av plasmaceller i beinmargen. Det finnes foreløpig ingen kurerende behandling, ...