Blar i Institutt for klinisk og molekylær medisin på tittel
Viser treff 3351-3370 av 3514
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Tumour size reduction after the first chemotherapy-course and outcomes of chemoradiotherapy in limited disease small-cell lung cancer
(Journal article; Peer reviewed, 2016)Objectives Concurrent chemotherapy and thoracic radiotherapy (TRT) is recommended for limited disease small-cell lung cancer (LD SCLC). TRT should start as early as possible, often meaning with the second course due to ... -
Tumour texture features from preoperative CT predict high-risk disease in endometrial cancer
(Peer reviewed; Journal article, 2020)BACKGROUND To enable more individualised treatment of endometrial cancer, improved methods for preoperative tumour characterization are warranted. Texture analysis is a method for quantification of heterogeneity in images, ... -
Tumour Vasculature in Subtypes of Breast Cancer
(Doctoral theses at NTNU;2019:35, Doctoral thesis, 2019)Breast cancer is a group of heterogeneous diseases. Using immunohistochemistry (IHC) and in situ hybridisation (ISH), they can be separated into molecular subtypes with distinct biology and prognosis. The Luminal A subtype ... -
Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications
(Peer reviewed; Journal article, 2021)Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility, easy processability, transparency, non-toxicity, and reasonable mechanical properties ... -
Turkish midwives’ experiences and opinions in promoting normal births: A grounded theory study
(Peer reviewed; Journal article, 2021)Introduction Worldwide, the biomedical model of maternity care has been dominant, with the overuse of interventions. Aim This study aimed to gain a deeper understanding of the experiences and opinions of Turkish ... -
Tverrfaglige legemiddelgjennomganger for kvalitetssikring av legemiddelbruk hos hjemmeboende eldre og sykehjemspasienter i Nord – Trøndelag: Effekter av læringsnettverk fra pasientsikkerhetskampanjen «I trygge hender»
(Master thesis, 2016)Bakgrunn: Riktig legemiddelbruk i sykehjem og hjemmetjenesten er to av innsatsområdene i nasjonal pasientsikkerhetskampanje «I trygge hender» (2011 – 2013). Fra desember 2013 til juni 2014 deltok kommuner i Nord – Trøndelag ... -
Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview.
(Journal article; Peer reviewed, 2019)Background: Enterovirus-D68 (EV-D68) is a respiratory virus within the genus Enterovirus and the family of Picornaviridae. Genetically, it is closely related to rhinovirus that replicates in the respiratory tract and causes ... -
Twice-daily thoracic radiotherapy in limited stage small-cell lung cancer
(Doctoral theses at NTNU;2023:156, Doctoral thesis, 2023)Norsk sammendrag Lungekreft er den kreftformen som forårsaker flest dødsfall. Lungekreft deles inn i to hovedtyper, ikke-småcellet (NSCLC) og småcellet lungekreft (SCLC). SCLC utgjør 13-15% av tilfellene og kjennestenges ... -
Twin Births: A Descriptive Study from Bwaila Hospital, Malawi
(Master thesis, 2009) -
"Two hits - one stone" increased efficacy of cisplatin-based therapies by targeting PCNA's role in both DNA repair and cellular signaling
(Journal article; Peer reviewed, 2018)Low response rate and rapid development of resistance against commonly used chemotherapeutic regimes demand new multi-targeting anti-cancer strategies. In this study, we target the stress-related roles of the scaffold ... -
Two-year motor outcomes associated with the dose of NICU based physical therapy: The Noppi RCT
(Peer reviewed; Journal article, 2022)Background Interventions involving both the parent and the preterm infant have demonstrated lasting effects on cognitive outcomes, but motor effects are less salient. It remains unclear when to commence early intervention ... -
TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer
(Journal article; Peer reviewed, 2014)Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, ... -
Type 2 cytokine genes as allergic asthma risk factors after viral bronchiolitis in early childhood
(Journal article; Peer reviewed, 2023) -
Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4
(Journal article; Peer reviewed, 2016)The innate immune system is the first line of defense against Neisseria gonorrhoeae (GC). Exposure of cells to GC lipooligosaccharides induces a strong immune response, leading to type I interferon (IFN) production via ... -
Types of Gastric Carcinomas
(Journal article; Peer reviewed, 2018)Gastric cancer has reduced prevalence, but poor prognoses. To improve treatment, better knowledge of carcinogenesis and cells of origin should be sought. Stomach cancers are typically localized to one of the three mucosae; ... -
Typical and Atypical Presentations of Gastroesophageal Reflux Disease Diagnostic and Therapeutic Challenges
(Doctoral thesis at NTNU;2015:79, Doctoral thesis, 2015) -
Tyrosine Kinase Inhibitors Target B Lymphocytes
(Peer reviewed; Journal article, 2023)Autoimmune disorders and some types of blood cancer originate when B lymphocytes malfunction. In particular, when B cells produce antibodies recognizing the body’s proteins, it leads to various autoimmune disorders. ... -
UDP-glucose dehydrogenase expression is upregulated following EMT and differentially affects intracellular glycerophosphocholine and acetylaspartate levels in breast mesenchymal cell lines
(Journal article; Peer reviewed, 2021)Metabolic rewiring is one of the indispensable drivers of epithelial-mesenchymal transition (EMT) involved in breast cancer metastasis. In this study, we explored the metabolic changes during spontaneous EMT in three ... -
Ulcer-associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase-associated lipocalin (NGAL) levels
(Peer reviewed; Journal article, 2019)Neutrophil gelatinase‐associated lipocalin (NGAL), also known as Lipocalin 2, is an antimicrobial protein, encoded by the gene LCN2, strongly upregulated in inflammatory bowel disease (IBD) and a promising biomarker for ... -
Ultrapure Wood Nanocellulose - Assessments of Coagulation and Initial Inflammation Potential
(Journal article; Peer reviewed, 2019)Using a lepirudin-based human whole blood model, we evaluated the initial inflammatory and coagulation responses of dense and porous ultrapure (<50 endotoxin units/grams) cellulose nanofibrils (CNF), of carboxylated grade. ...