Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 2352-2371 of 3589
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O-GlcNAc Transferase Inhibition Differentially Affects Breast Cancer Subtypes
(Journal article; Peer reviewed, 2019)Post-translational modification of intracellular proteins with a single N-acetylglucosamine sugar (O-GlcNAcylation) regulates signaling, proliferation, metabolism and protein stability. In breast cancer, expression of the ... -
Obesity does not protect from subarachnoid haemorrhage: Pooled analysis of 3 large prospective Nordic cohorts
(Journal article; Peer reviewed, 2021)Background and Purpose: Several population-based cohort studies have related higher body mass index (BMI) to a decreased risk of subarachnoid hemorrhage (SAH). The main objective of our study was to investigate whether ... -
Obesity Knowledge amongst final year medical students in Norway
(Journal article; Peer reviewed, 2017)Objectives: To assess the level of obesity knowledge in final-year medical students in Norway and to compare it to an expert group and first-year medical students. Methods: A 20-item questionnaire was specifically designed ... -
Obesity, adipose tissue dysfunction and metabolic disease: possible roles of GPD1L
(Master thesis, 2014) -
Obesity, diabetes and hypovitaminosis D among women in a rural district of Nepal: Prevalence and risk factors. A population-based study
(Doctoral theses at NTNU;2024:143, Doctoral thesis, 2024)The prevalence of obesity, diabetes, and hypovitaminosis D has increased worldwide over the last decades, and these conditions have reached epidemic proportions. Low- and middleincome countries have experienced the most ... -
Octogenarian patients with colon cancer – postoperative morbidity and mortality are the major challenges
(Peer reviewed; Journal article, 2022)Background Few studies have addressed colon cancer surgery outcomes in an unselected cohort of octogenarian patients. The present study aimed to evaluate the relative survival of octogenarian patients after a major resection ... -
Oestrogen receptor low positive breast cancer: associations with prognosis
(Journal article; Peer reviewed, 2023)Purpose In this study of oestrogen receptor (ER) Low Positive breast cancers (BC) in three large cohorts of BC patients, we assess associations between levels of ER expression and tumour characteristics and prognosis. ... -
‘Ok, stranger fetus-baby: I love you’ The ethics of life and death decisions at the border of viability
(Doctoral theses at NTNU;2023:343, Doctoral thesis, 2023)Advances in neonatal medicine have allowed us to rescue extremely preterm infants. However, both long-term vulnerability and the burden of treatment in the neonatal period increase with decreasing gestational age. Some of ... -
Olaparib monotherapy as primary treatment in unselected triple negative breast cancer
(Peer reviewed; Journal article, 2020)Background The antitumor efficacy of PARP inhibitors (PARPi) for breast cancer patients harboring germline BRCA1/2 (gBRCA1/2) mutations is well established. While PARPi monotherapy was ineffective in patients with metastatic ... -
Older patients with colorectal cancer at Levanger Hospital 1980-2016
(Doctoral theses at NTNU;2023:255, Doctoral thesis, 2023)Kreft i tykk- og endetarm har blitt den vanligste kreftsykdommen i Norge med unntak av brystkreft for kvinner og prostatakreft for menn. Sykdommen rammer i hovedsak eldre mennesker og har en insidens-topp rundt 70 års ... -
Omics and Male Infertility: Highlighting the Application of Transcriptomic Data
(Peer reviewed; Journal article, 2022)Male infertility is a multifaceted disorder affecting approximately 50% of male partners in infertile couples. Over the years, male infertility has been diagnosed mainly through semen analysis, hormone evaluations, medical ... -
Omskjæring hos kvinner bosatt i Norge – konsekvenser og behandling
(Peer reviewed; Journal article, 2021)BAKGRUNN Poliklinikktilbud for kvinner som har gjennomgått omskjæring finnes ved syv norske sykehus. I vår studie presenteres symptomer, funn og behandling hos kvinner som ble undersøkt ved poliklinikkene i perioden ... -
On the Identification of Features of Aggressive Breast Cancer Development
(Doctoral theses at NTNU;2019:68, Doctoral thesis, 2019)Innføring av nasjonale mammografiprogrammer har ført til en økning av antall brystkrefttilfeller; først og fremst ikke-invasive tumorer. Vi vet at få av disse svulstene vil bli mestastatiske og dødelige, men vi mangler i ... -
On the prognostic factors of low-grade gliomas
(Doctoral theses at NTNU;2020:139, Doctoral thesis, 2020)Hjernesvulsters egenskaper i forløpet ved hjernekreft Gliomer er den vanligste typen av primære maligne hjernesvulster og disse rammer ca. 6 personer per 100 000 per år. Gliomer graderes ved mikroskopisk cellebilde og ... -
On the role of phosphatase of regenerating liver (PRL-) 3 in cell signaling and metabolism in multiple myeloma
(Doctoral theses at NTNU;2021:275, Doctoral thesis, 2021) -
On the susceptibility and adaptability of beta cells to stressful conditions: effects of nutrient scarcity, hyperoxia and internalization of amylin
(Doctoral theses at NTNU;2018:26, Doctoral thesis, 2018) -
Onkologisk behandling av stadium I-III ikke-småcellet lungekreft ved St. Olavs hospital i perioden 2010-2014
(Master thesis, 2016)Mål: Å undersøke resultatet av høydosert strålebehandling gitt til inoperable pasienter med stadium I-‐III ikke-‐småcellet lungekreft ved kreftklinikken, St. Olavs Hospital. Hvordan er bivirkningene, responsen, responsvarighet ... -
Online Patient Information about Breast Cancer – A Discourse Analysis
(Journal article; Peer reviewed, 2017)Adequate information is crucial for patient participation in health trajectories. The objective of this study is to analyse how online health information about cancer is organised and presented. Updated information about ... -
Open chest and pericardium facilitate transpulmonary passage of venous air emboli
(Peer reviewed; Journal article, 2021)Background Transpulmonary passage of air emboli can lead to fatal brain- and myocardial infarctions. We studied whether pigs with open chest and pericardium had a greater transpulmonary passage of venous air emboli than ... -
Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness study
(Journal article; Peer reviewed, 2016)Introduction: Since the introduction of lumbar microdiscectomy in the 1970’s, many studies have attempted to compare the effectiveness of this method with that of standard open discectomy with conflicting results. This ...