Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 913-932 of 3438
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Early Parent-Administered Physical Therapy for Preterm Infants: A Randomized Controlled Trial
(Peer reviewed; Journal article, 2016)OBJECTIVE: To investigate the short-term effect of parent-administered physical therapy in the preterm period on motor performance in medically stable infants. METHODS: This study was a pragmatic, multicenter, randomized ... -
Early postnatal nutrition after preterm birth and cardiometabolic risk factors in young adulthood
(Journal article; Peer reviewed, 2018)Objectives Adults born preterm at very low birthweight (VLBW; <1500 g) have a non-optimal cardiometabolic risk factor profile. Since higher protein intake during the first weeks of life predicted a healthier body ... -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
(Journal article; Peer reviewed, 2022) -
Early self-reported pain in juvenile idiopathic arthritis (JIA) is related to long-term outcomes. Results from the Nordic JIA cohort study.
(Journal article; Peer reviewed, 2018)Objective To study self‐reported pain early in the disease course of juvenile idiopathic arthritis (JIA) as predictor of long‐term disease outcomes. Methods Consecutive cases of JIA with disease onset 1997‐2000 from ... -
Early skin-to-skin contact or incubatorfor very preterm infants: study protocol for a randomized controlled trial
(Journal article; Peer reviewed, 2016)Background Skin-to-skin care immediately following delivery is a common practice for term infants and has been shown to improve cardiorespiratory stability, facilitate early bonding, and promote breastfeeding. Since ... -
Early, accurate diagnosis and early intervention in cerebral palsy: Advances in diagnosis and treatment
(Journal article; Peer reviewed, 2017)Importance Cerebral palsy describes the most common physical disability in childhood and occurs in 1 in 500 live births. Historically, the diagnosis has been made between age 12 and 24 months but now can be made before 6 ... -
Early-Life Factors as Predictors of Age-Associated Deficit Accumulation Across 17 Years From Midlife Into Old Age
(Journal article; Peer reviewed, 2022) -
Ectonucleotidase CD39 and Checkpoint Signalling Receptor Programmed Death 1 are Highly Elevated in Intratumoral Immune Cells in Non–small-cell Lung Cancer
(Journal article; Peer reviewed, 2019)Lung cancer is the leading cause of cancer death in both sexes worldwide and has a predicted 5-year survival rate of <20%. Immunotherapy targeting immune checkpoints such as the programmed death 1 (PD-1) signaling pathway ... -
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn
(Journal article; Peer reviewed, 2015)Eculizumab is a humanized IgG2/4 chimeric anti-complement C5 antibody used to treat patients with paroxysmal nocturnal hemoglobinuria (PNH) or atypical hemolytic uremic syndrome. The aim of this study was to evaluate whether ... -
Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses
(Journal article; Peer reviewed, 2017)The complement system has obtained renewed clinical focus due to increasing number of patients treated with eculizumab, a monoclonal antibody inhibiting cleavage of C5 into C5a and C5b. The FDA approved indications are ... -
Editorial: Protection and healing in the digestive system and other tissues: Novel factors, mechanisms, and pharmaceutical targets
(Peer reviewed; Journal article, 2022) -
Edmonton Frail Scale predicts mortality in older patients with cancer undergoing radiotherapy-A prospective observational study
(Peer reviewed; Journal article, 2023)Background: Several screening tools are developed to identify frailty in the increasing number of older patients with cancer. Edmonton Frail Scale (EFS) performs well in geriatric settings but is less studied in oncology. ... -
Effect of a cod protein hydrolysate on postprandial glucose metabolism in healthy subjects: A double-blind cross-over trial
(Journal article; Peer reviewed, 2018)The increased prevalence of lifestyle diseases, such as the metabolic syndrome and type 2 diabetes mellitus (T2DM), calls for more knowledge on dietary treatments targeting the specific metabolic pathways involved in these ... -
Effect of a ketogenic diet on pain and quality of life in patients with lipedema: The LIPODIET pilot study
(Peer reviewed; Journal article, 2021)Background Lipedema is an underdiagnosed condition in women, characterized by a symmetrical increase in subcutaneous adipose tissue (SAT) in the lower extremities, sparing the trunk. The lipedema SAT has been found to be ... -
Effect of a multifaceted educational program for care staff concerning fecal incontinence in nursing home patients: Study protocol of a cluster randomized controlled trial
(Journal article; Peer reviewed, 2015)Background Fecal incontinence has a high prevalence in the older population, which cannot be explained by comorbidity or the anatomical or psychological changes of aging alone. Fecal incontinence leads to a high economic ... -
Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial
(Journal article; Peer reviewed, 2016)Aims Interleukin-6 (IL-6) contributes to atherosclerotic plaque destabilization and is involved in myocardial injury during ischaemia–reperfusion. Interleukin-6 is therefore a potential therapeutic target in myocardial ... -
Effect of acoustic cluster therapy (ACT®) combined with chemotherapy in a patient-derived xenograft mouse model of pancreatic cancer
(Peer reviewed; Journal article, 2022)Pancreatic ductal adenocarcinomas respond poorly to chemotherapy, in part due to the dense tumor stroma that hinders drug delivery. Ultrasound (US) in combination with microbubbles has previously shown promise as a means ... -
Effect of Acoustic Radiation Force on the Distribution of Nanoparticles in Solid Tumors.
(Peer reviewed; Journal article, 2020)Acoustic radiation force (ARF) might improve the distribution of nanoparticles (NPs) in tumors. To study this, tumors growing subcutaneously in mice were exposed to focused ultrasound (FUS) either 15 min or 4 h after the ... -
Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity-A Randomized Controlled Trial
(Peer reviewed; Journal article, 2021)Objective This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure. Methods This was a single‐center randomized controlled trial of patients with severe obesity ...