Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 404-423 of 3438
-
Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors?
(Journal article; Peer reviewed, 2015)Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this hypothesis-generating, ... -
Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling
(Journal article; Peer reviewed, 2017)The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ... -
Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆
(Peer reviewed; Journal article, 2021) -
Cancer Cachexia: Classification, Pathophysiology and Treatment
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:49, Doctoral thesis, 2014)Cachexia is a very common condition in patients with cancer and it has detrimental effects on both mortality and morbidity. Cachexia is characterized by progressive unintentional loss of muscle mass, with or without loss ... -
Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial
(Journal article; Peer reviewed, 2018)Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a ... -
Cancer incidence and risk of multiple cancers after environmental asbestos exposure in childhood—a long-term register-based cohort study
(Peer reviewed; Journal article, 2022)Objectives: To examine the asbestos-associated cancer incidence and the risk of multiple cancers in former school children exposed to environmental asbestos in childhood. Methods: A cohort of 12,111 former school children, ... -
Cancer induced bone pain
(Doctoral theses at NTNU;2024:38, Doctoral thesis, 2024)Bone metastases causing cancer induced bone pain (CIBP) is one of the most frequent reasons for pain in patients with cancer. Although pain is a common consequence of bone metastases, not all patients with bone metastases ... -
Cancer pain assessment, classification and patient reported outcomes in the evaluation of treatment effect
(Doctoral theses at NTNU;2016:328, Doctoral thesis, 2016)Pain is common in patients with cancer and it has a strong impact on quality of life. Despite the development of guidelines, cancer pain treatment is suboptimal. This is often due to lack of efficient, standardized and ... -
Cancer pain classification
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:112, Doctoral thesis, 2012)Klassifikasjon av kreftsmerte Kreftsmerte – hva skal et fremtidig klassifikasjonssystem inneholde? Smerte er et subjektivt, sammensatt og plagsomt symptom som forekommer hyppig hos kreftpasienter. Til tross for eksisterende ... -
Cancer pain – clinical studies on prevalence and treatment with nasal fentanyl
(Doctoral thesis at NTNU;2016:81, Doctoral thesis, 2016)Summary in English: Pain is one of the most feared symptoms among cancer patients. Studies show that about 50% of all cancer patients experience pain and these numbers are increasing for patients with advanced disease. ... -
Cancer patients spend more time at home and more often die at home with advance care planning conversations in primary health care: a retrospective observational cohort study
(Peer reviewed; Journal article, 2022)Background Spending time at home and dying at home is advocated to be a desirable outcome in palliative care (PC). In Norway, home deaths among cancer patients are rare compared to other European countries. Advance care ... -
Cancer patients' knowledge about their disease and treatment before, during and after treatment: a prospective, longitudinal study
(Journal article; Peer reviewed, 2018)Background Knowledge about disease and treatment is necessary before patients can consent to treatment. One of the few established instruments for evaluating whether sufficient information has been provided, is the EORTC ... -
Cancer Patients’ Perceived Value of a Smartphone App to Enhance the Safety of Home-Based Chemotherapy: Feasibility Study
(Journal article; Peer reviewed, 2020)Background: Oral anticancer therapies can be self-administered by patients outside the hospital setting, which poses challenges of adherence to a drug plan and monitoring of side effects. Modern information technology ... -
Cancer Stem Cells and Their Possible Implications in Cervical Cancer: A Short Review
(Peer reviewed; Journal article, 2022)Cervical cancer (CC) is the fourth most common type of gynecological malignancy affecting females worldwide. Most CC cases are linked to infection with high-risk human papillomaviruses (HPV). There has been a significant ... -
Cancer therapy and risk of congenital malformations in children fathered by men treated for testicular germ-cell cancer: A nationwide register study
(Journal article; Peer reviewed, 2019)Background Because of the potential mutagenic effects of chemo- and radiotherapy, there is concern regarding increased risk of congenital malformations (CMs) among children of fathers with cancer. Previous register studies ... -
Carbon nanofibers have IgE adjuvant capacity but are less potent than nanotubes in promoting allergic airway responses
(Journal article; Peer reviewed, 2013)There is a growing concern for the possible health impact of nanoparticles. The main objective of this study was to investigate the allergy-promoting capacity of four different carbon nanofiber (CNF) samples in an injection ... -
Cardiac Dysfunction and Arrhythmias 3 Months After Hospitalization for COVID-19
(Peer reviewed; Journal article, 2022)Background - The extent of cardiac dysfunction post‐COVID‐19 varies, and there is a lack of data on arrhythmic burden. Methods and Results - This was a combined multicenter prospective cohort study and cross‐sectional ... -
Cardiopulmonary and muscular effects of different doses of high-intensity physical training in substance use disorder patients: study protocol for a block allocated controlled endurance and strength training trial in an inpatient setting
(Peer reviewed; Journal article, 2022)Introduction Patients with substance use disorder (SUD) have high prevalence of lifestyle-related comorbidities. Physical exercise is known to yield substantial prophylactic impact on disease and premature mortality, and ... -
Cardiorenal syndrome and the association with fitness: Data from a telerehabilitation randomized clinical trial
(Peer reviewed; Journal article, 2022)Aims To investigate the associations of cardiorespiratory fitness with cardiac, vascular, renal and cardiorenal characteristics in chronic heart failure in a telerehabilitation randomized clinical trial. Secondly, to ... -
Cardiorespiratory fitness and mortality in rheumatoid arthritis
(Doctoral theses at NTNU;2022:128, Doctoral thesis, 2022)Background Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that affects synovial joints and internal organs. It affects around 1% of the population, and the disease is associated with increased all-cause ...