Browsing Institutt for klinisk og molekylær medisin by Title

Now showing items 391-410 of 3434

    • c-Myb Binding Sites in Haematopoietic Chromatin Landscapes 

      Bengtsen, Mads; Klepper, Kjetil; Gundersen, Sveinung; Cuervo, Ignacio; Drabløs, Finn; Hovig, Johannes Eivind; Sandve, Geir Kjetil F.; Gabrielsen, Odd Stokke; Eskeland, Ragnhild (Journal article, 2015)
      Strict control of tissue-specific gene expression plays a pivotal role during lineage commit- ment. The transcription factor c-Myb has an essential role in adult haematopoiesis and func- tions as an oncogene when rearranged ...

    • Caesarean birth experiences. A qualitative study from Sierra Leone. 

      Husby, Anne; van Duinen, Aalke Johan; Aune, Ingvild (Journal article; Peer reviewed, 2019)
      Background Positive birth experiences lead to better postnatal functioning, and influence mode of delivery choice for subsequent pregnancies. Healthcare workers can influence the birth experience through relevant support ...

    • Caesarean section in women with axial spondyloarthritis and psoriatic arthritis: a population-based study 

      Skorpen, Anna Carina G.; Lydersen, Stian; Salvesen, Kjell Åsmund Blix; Koksvik, Hege; Jakobsen, Bente; Wallenius, Marianne (Peer reviewed; Journal article, 2023)
      Background There is sparse documentation on pregnancy outcomes in women with axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). Data on disease activity are often lacking, preventing the direct investigation ...

    • Caesarean section performed by medical doctors and associate clinicians in Sierra Leone 

      van Duinen, Aalke Johan; Kamara, Michael M.; Hagander, Lars; Ashley, Thomas; Koroma, Alimamy Philip; Leather, Andy J.M.; Elhassein, Mohammed; Darj, Elisabeth; Salvesen, Øyvind; Wibe, Arne; Bolkan, Håkon Angell (Journal article; Peer reviewed, 2019)
      Background Many countries lack sufficient medical doctors to provide safe and affordable surgical and emergency obstetric care. Task‐sharing with associate clinicians (ACs) has been suggested to fill this gap. The aim ...

    • Caesarean Sections in Sierra Leone An Evaluation in the Light of the Lancet Global Surgery Indicators 

      Duinen, Aalke Johan van (Doctoral theses at NTNU;2021:402, Doctoral thesis, 2021)
      Background: Two third of the world’s population does not have adequate access to timely safe and affordable surgical services. The Lancet Commission on Global Surgery has defined a framework with six indicators and targets ...

    • Calprotectin and CRP as biomarkers of cardiovascular disease risk in patients with chronic kidney disease: a follow-up study at 5 and 10 years 

      Løfblad, Lena; Hov, Gunhild Garmo; Åsberg, Arne; Videm, Vibeke (Peer reviewed; Journal article, 2023)
      Chronic kidney disease (CKD) and low-grade inflammation are associated with increased risk of cardiovascular disease (CVD). Calprotectin, a protein mainly secreted by activated neutrophils during inflammatory conditions, ...

    • Camp-based family treatment of childhood obesity: randomised controlled trial 

      Benestad, Beate; Lekhal, Samira; Småstuen, Milada C; Hertel, Jens Kristoffer; Halsteinli, Vidar; Ødegård, Rønnaug Astri; Hjelmesæth, Jøran (Peer reviewed; Journal article, 2017)
      Objective To compare the effectiveness of a 2-year camp-based family treatment programme and an outpatient programme on obesity in two generations. Design Pragmatic randomised controlled trial. Setting Rehabilitation ...

    • Can a Dinosaur Think? Implementation of Artificial Intelligence in Extracorporeal Shock Wave Lithotripsy 

      Muller, Sebastien; Abildsnes, Håkon; Østvik, Andreas; Kragset, Oda; Gangås, Inger Sofie Hovd; Birke, Harriet; Langø, Thomas; Arum, Carl-Jørgen (Peer reviewed; Journal article, 2021)
      Background: Extracorporeal shock wave lithotripsy (ESWL) of kidney stones is losing ground to more expensive and invasive endoscopic treatments. Objective: This proof-of-concept project was initiated to develop artificial ...

    • Can a Peritoneal Conduit Become an Artery? 

      Davik, Petter; Chabadova, Zuzana; Altreuther, Martin; Leinan, Ingeborg Megård; Bandaru, Sashidar; Akyürek, Levent M; Mattsson, Erney (Peer reviewed; Journal article, 2020)
      Objective Current vascular grafts all have limitations. This study examined peritoneum as a potential graft material and the in vivo transfer of peritoneum into a functional artery like conduit after end to end anastomosis ...

    • Can clothing systems and human activities in operating rooms with mixing ventilation systems help achieve 10 CFU/m3 level during orthopaedic surgeries? 

      Cao, Guangyu; Pedersen, Christoffer; Zhang, Yixian; Drangsholt, Finn; Radtke, Andreas; Langvatn, Håkon; Stenstad, Liv-Inger; Mathisen, Hans Martin; Skogås, Jan Gunnar (Journal article, 2021)
      The level of airborne microbial contamination in operating rooms (ORs) is an important indicator of indoor air quality and ensures a clean surgical environment. It is necessary to research how different factors affect the ...

    • Can oxytocin augmentation modify the risk of epidural analgesia by maternal age in cesarean sections? 

      Rossen, Janne; Klungsøyr, Kari; Albrechtsen, Susanne; Løkkegård, Ellen; Rasmussen, Steen; Bergholt, Thomas; Skjeldestad, Finn Egil (Journal article; Peer reviewed, 2018)
      Introduction Maternal age is an established risk factor for cesarean section; epidural analgesia and oxytocin augmentation may modify this association. We investigated the effects and interactions of oxytocin augmentation, ...

    • Can spectral-spatial image segmentation be used to discriminate experimental burn wounds? 

      Paluchowski, Lukasz A.; Nordgaard, Håvard B.; Bjorgan, Asgeir; Hov, Håkon; Berget, Sissel Marie; Randeberg, Lise Lyngsnes (Journal article; Peer reviewed, 2016)
      Hyperspectral imaging (HSI) is a noncontact and noninvasive optical modality emerging the field of medical research. The goal of this study was to determine the ability of HSI and image segmentation to discriminate burn ...

    • Can ultrasound predict labor outcome in operative vaginal deliveries? 

      Kahrs, Birgitte Heiberg (Doctoral theses at NTNU;2020:183, Doctoral thesis, 2020)

    • Can variability in the effect of opioids on refractory breathlessness be explained by genetic factors? 

      Currow, David C.; Quinn, Stephen; Ekström, Magnus; Kaasa, Stein; Johnson, Miriam J.; Somogyi, Andrew A.; Klepstad, Pål (Journal article; Peer reviewed, 2015)
      Objectives: Opioids modulate the perception of breathlessness with a considerable variation in response, with poor correlation between the required opioid dose and symptom severity. The objective of this hypothesis-generating, ...

    • Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling 

      Pettersen, Kristine; Andersen, Sonja Benedikte; Degen, simone; Tadini, Valentina; Grosjean, Joel; Hatakeyama, Shinji; Tesfahun, Almaz Nigatu; Moestue, Siver Andreas; Kim, Jana; Nonstad, Unni; Romundstad, Pål Richard; Skorpen, Frank; Sørhaug, Sveinung; Amundsen, Tore; Grønberg, Bjørn Henning; Strasser, Florian; Stephens, Nathan; Hoem, Dag; Molven, Anders; Kaasa, Stein; Fearon, Kenneth; Jacobi, Carsten; Bjørkøy, Geir (Journal article; Peer reviewed, 2017)
      The majority of cancer patients with advanced disease experience weight loss, including loss of lean body mass. Severe weight loss is characteristic for cancer cachexia, a condition that significantly impairs functional ...

    • Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines☆ 

      Arends, Jann; Strasser, Florian; Gonella, Silvia; Solheim, Tora S; Madeddu, Christina; Ravasco, Paula; Buonaccorso, Loredana; de van der Schueren, Marion; Baldwin, Christine; Chasen, Martin; Ripamonti, Carla (Peer reviewed; Journal article, 2021)

    • Cancer Cachexia: Classification, Pathophysiology and Treatment 

      Solheim, Tora Skeidsvoll (Doktoravhandlinger ved NTNU, 1503-8181; 2014:49, Doctoral thesis, 2014)
      Cachexia is a very common condition in patients with cancer and it has detrimental effects on both mortality and morbidity. Cachexia is characterized by progressive unintentional loss of muscle mass, with or without loss ...

    • Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial 

      Solheim, Tora Skeidsvoll; Laird, Barry J. A.; Balstad, Trude Rakel; Bye, Asta; Stene, Guro Birgitte; Baracos, Vickie; Strasser, Florian; Griffiths, Gareth; Maddocks, Matthew; Fallon, Marie; Kaasa, Stein; Fearon, Kenneth (Journal article; Peer reviewed, 2018)
      Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a ...

    • Cancer incidence and risk of multiple cancers after environmental asbestos exposure in childhood—a long-term register-based cohort study 

      Dalsgaard, Sofie Bünemann; Würtz, Else Toft; Hansen, Johnni; Røe, Oluf Dimitri; Omland, Øyvind (Peer reviewed; Journal article, 2022)
      Objectives: To examine the asbestos-associated cancer incidence and the risk of multiple cancers in former school children exposed to environmental asbestos in childhood. Methods: A cohort of 12,111 former school children, ...

    • Cancer induced bone pain 

      Habberstad, Ragnhild (Doctoral theses at NTNU;2024:38, Doctoral thesis, 2024)
      Bone metastases causing cancer induced bone pain (CIBP) is one of the most frequent reasons for pain in patients with cancer. Although pain is a common consequence of bone metastases, not all patients with bone metastases ...