Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 171-190 of 3438
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APIM-PCNA Interactions in the Regulation of Cellular Stress Responses
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:365, Doctoral thesis, 2013) -
APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer
(Journal article; Peer reviewed, 2018)Docetaxel is the chemotherapeutic choice for metastatic hormone-refractory prostate cancer, however, it only marginally improves the survival rate. The purpose of the present study was to examine if a peptide ... -
APOE Polymorphism and Endocrine Functions in Subjects with Morbid Obesity Undergoing Bariatric Surgery
(Peer reviewed; Journal article, 2022)Background: Obesity is an interplay between genes and the environment, including lifestyle. The genetics of obesity is insufficiently understood. Apolipoprotein E (APOE) genetic polymorphism has been associated with a wide ... -
APOE Polymorphism Is Associated with Changes in the Kynurenine Pathway
(Peer reviewed; Journal article, 2023)Abstract: Background: APOE polymorphism and the Kynurenine pathway (KP) are associated with many disorders, but little is known about associations between APOE polymorphism and the KP. This study explored the associations ... -
APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; a case control study from central Norway
(Journal article; Peer reviewed, 2008)Background: The objective of this study was to analyze factors influencing the risk and timing of Alzheimer's disease (AD) in central Norway. The APOE ε4 allele is the only consistently identified risk factor for late ... -
APOE – a genetic marker of comorbidity in subjects with morbid obesity
(Peer reviewed; Journal article, 2020)Background In population-based studies, the genetic variability of the APOE E alleles have been associated with health outcomes. Health problems are common in subjects with obesity. This study explored associations ... -
Apolipoprotein E and Cerebral Palsy: A Cross-sectional Study of the Influence of Genetic Variation on Clinical Manifestations of CP
(Doctoral thesis at NTNU;2015:246, Doctoral thesis, 2015)Cerebral palsy (CP) is the most common neurodevelopmental disorder in children, showing varying degrees of motor impairments, activity limitations and accompanying disturbances of function. A long-held belief has been ... -
Apotekansatte farmasøyters rolle som livsstilsveiledere
(Master thesis, 2020)SAMMENDRAG Bakgrunn: I nyere tid har det blitt et stort fokus på ernæring, kosthold og trening og det er stadig flere mennesker som bryr seg om livsstilen sin. Det har for eksempel blitt rettet mye fokus på livsstilstiltak ... -
Appetite in obesity and subsequent effects of weight loss induced by dietary restriction alone or combined with bariatric surgery
(Doctoral theses at NTNU;2023:71, Doctoral thesis, 2023) -
Application of photodynamic therapy with 5-aminolevulinic acid to extracorporeal photopheresis in the treatment of patients with chronic graft-versus-host disease: A first-in-human study
(Peer reviewed; Journal article, 2021)Extracorporeal photopheresis (ECP), an immunomodulatory therapy for the treatment of chronic graft-versus-host disease (cGvHD), exposes isolated white blood cells to photoactivatable 8-methoxypsoralen (8-MOP) and UVA light ... -
Applying genetic engineering tools in zebrafish to study the neuromodulatory role of the choroid plexus
(Master thesis, 2022)Choroid plexus er et organ som produserer mesteparten av cerebrospinalvæsken (CSV) i kroppen. Denne væsken omslutter hjernen og demper mekaniske slag samtidig som den bidrar til naturlig sirkulering av næring og avfallstoffer. ... -
Applying Unsterile Microporous Tape onto Surgical Wounds: Tape Contamination and Clinical Rationale
(Peer reviewed; Journal article, 2021)Background: Fomites are surfaces that carry contaminants and may cause infection. We wanted to assess the bacterial load on rolls of nonsterile microporous tape in a hospital setting and explore the scientific rationale ... -
Approved claims for compensation from gynecological patients in Norway?What characterizes the cases? A 14-year nationwide study
(Journal article; Peer reviewed, 2019)Introduction: The Norwegian System of Patient Injury Compensation (NPE) evalu-ates all patient‐reported claims in Norway. Our aim was to study the cases from gy-necological patients approved by NPE in order to identify the ... -
Arabidopsis myrosinases link the glucosinolate-myrosinase system and the cuticle.
(Journal article; Peer reviewed, 2016)Both physical barriers and reactive phytochemicals represent two important components of a plant’s defence system against environmental stress. However, these two defence systems have generally been studied independently. ... -
Are emergency admissions in palliative cancer care always necessary? Results from a descriptive study
(Journal article; Peer reviewed, 2013)Objectives: Patients with advanced cancer are often admitted to hospital as emergency cases. This may not always be medically indicated. Study objectives were to register the reasons for the emergency admissions, to examine ... -
Are faecal microbiota analyses on species-level suitable clinical biomarkers? A pilot study in subjects with morbid obesity
(Journal article; Peer reviewed, 2021)Background: An abnormal faecal microbiota could be a causal factor for disease. This study evaluated a new method for faecal microbiota analysis in subjects with obesity and irritable bowel syndrome. Methods: The study had ... -
Are levator hiatal dimensions in mid-pregnancy associated with mode of delivery?
(Peer reviewed; Journal article, 2022)Introduction and hypothesis Slow progress of labour is a risk for operative delivery. Smaller levator hiatal dimensions are possible risk factors for slow progress and operative delivery. Our aim was to explore associations ... -
Are levator hiatal dimensions in mid-pregnancy associated with mode of delivery?
(Peer reviewed; Journal article, 2022)Introduction and hypothesis - Slow progress of labour is a risk for operative delivery. Smaller levator hiatal dimensions are possible risk factors for slow progress and operative delivery. Our aim was to explore associations ... -
Are mirror movements associated with bimanual hand function among children with unilateral spastic cerebral palsy?
(Master thesis, 2016)Children and adolescents with unilateral spastic cerebral palsy (USCP) may experience mirror movements (MM). The amount of MM may indicate differences in the organization of the cortico-spinal motor tracts, which may ... -
Are Nonnutritive Sweeteners Obesogenic? Associations between Diet, Faecal Microbiota, and Short-Chain Fatty Acids in Morbidly Obese Subjects
(Journal article; Peer reviewed, 2019)Obesity has been associated with changes in the gut microbiota and its metabolites. The study explored changes in the faecal microbiota and short-chain fatty acids (SCFA) associated with the diet (including nonnutritive ...