Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1644-1663 of 3443
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Induction of labor in twin pregnancies – A retrospective cohort study
(Journal article; Peer reviewed, 2022) -
Infant Motor Assessment, Long-Term Clinical Outcome, Quantitative Cerebral MRI and Cognitive Training in Children Born Preterm with Very Low Birth Weight
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:257, Doctoral thesis, 2014)The preterm birth incidence and survival rates have been increasing over the last few decades due to advances in obstetric care and neonatal treatment. Despite this, the number of preterm children that develop severe ... -
Inferring causative variants in microRNA target sites
(Journal article; Peer reviewed, 2011)MicroRNAs (miRNAs) regulate genes post transcription by pairing with messenger RNA (mRNA). Variants such as single nucleotide polymorphisms (SNPs) in miRNA regulatory regions might result in altered protein levels and ... -
Inferring regulatory networks and dynamical activities of transcription factors and miRNAs
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:182, Doctoral thesis, 2014)Transcription factors (TFs) and miRNAs are fundamental regulators of gene expression. Transcription factors are proteins that regulate the process of transcribing genes in the DNA into mRNA, whereas miRNAs mainly regulate ... -
Inflammasome Activator Nigericin Induces Apoptosis in Myeloma cells
(Master thesis, 2015)Multiple myeloma (MM) is a neoplastic disorder of plasma cells. Research has shown that cytokines act as a double edged sword in tumour microenvironment to facilitate MM cell homing, survival, proliferation and pathogenesis. ... -
The inflammasome components NLRP3 and ASC act in concert with IRGM to rearrange the golgi apparatus during hepatitis C virus infection
(Peer reviewed; Journal article, 2021)Hepatitis C virus (HCV) infection triggers Golgi fragmentation through the Golgi-resident protein immunity-related GTPase M (IRGM). Here, we report the roles of NLRP3 (NOD-, LRR- and pyrin domain-containing protein 3) and ... -
Inflammation and atherosclerosis: Risk associations in the HUNT surveys
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:155, Doctoral thesis, 2012) -
Inflammation and Digestive Cancer
(Journal article; Peer reviewed, 2023)Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, i.e., the stomach, colon, and liver. The mechanism of this effect has, however, only partly been focused on. In this review, we focus ... -
Inflammation and Digestive Cancer
(Peer reviewed; Journal article, 2023)Chronic inflammation is linked to carcinogenesis, particularly in the digestive organs, i.e., the stomach, colon, and liver. The mechanism of this effect has, however, only partly been focused on. In this review, we focus ... -
Inflammation and Risk Prediction of Major Complications Following Cardiac Surgery
(Doctoral thesis at NTNU;2015:224, Doctoral thesis, 2015)Background In cardiac surgery improvements in quality of care have been a major focus for several decades. Statistical models for predicting the risk of operative mortality and other adverse outcomes have been an important ... -
Inflammation by pattern recognition receptors in the uterine wall decidua and the placenta of normal and preeclamptic pregnancies
(Doctoral theses at NTNU;2020:207, Doctoral thesis, 2020)Preeclampsia is a serious inflammatory disorder characterized by hypertension and proteinuria in the second half of pregnancy. It is often associated with severe maternal and fetal complications, such as fetal growth ... -
Inflammation in Pregnancy – A Study of Pattern Recognition Receptors in Trophoblasts
(Master thesis, 2011)Normal pregnancy is characterized by a mildly elevated state of inflammation, as a consequence of the woman’s body adapting to the presence of the growing fetus. The placenta is established in early pregnancy, and constitutes ... -
Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality
(Peer reviewed; Journal article, 2022)In the general population low-grade inflammation has been established as a risk factor for all-cause mortality. We hypothesized that an inflammatory milieu beyond the time of recovery from the surgical trauma could be ... -
Inflammation Is Strongly Associated With Cardiorespiratory Fitness, Sex, BMI, and the Metabolic Syndrome in a Self-reported Healthy Population: HUNT3 Fitness Study
(Journal article; Peer reviewed, 2019)Objective To investigate whether C-reactive protein (CRP, a general marker of inflammation), neopterin (activated macrophages), lactoferrin (activated neutrophils), and endothelial function (flow-mediated vasodilation ... -
Inflammation markers in multiple sclerosis: CXCL16 reflects and may also predict disease activity
(Journal article; Peer reviewed, 2013)Background: Serum markers of inflammation are candidate biomarkers in multiple sclerosis (MS). ω-3 fatty acids are suggested to have anti-inflammatory properties that might be beneficial in MS. We aimed to explore ... -
Inflammation mediates approximately one quarter of excess relative all-cause mortality in persons with rheumatoid arthritis: the Trøndelag Health Study
(Peer reviewed; Journal article, 2022)Inflammation may contribute to excess mortality in rheumatoid arthritis (RA) patients. We investigated associations to all-cause mortality of the inflammation markers high-sensitivity C-reactive protein (CRP), lactoferrin ... -
Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: Results of a 5-year follow-up cohort study
(Journal article; Peer reviewed, 2019)Background Biomarkers may facilitate clinical decisions in order to guide antimicrobial treatment and prediction of prognosis in community-acquired pneumonia (CAP). We measured serum C-reactive protein, procalcitonin (PCT) ... -
Inflammatory Biomarkers Can Differentiate Acute Lymphoblastic Leukemia with Arthropathy from Juvenile Idiopathic Arthritis Better Than Standard Blood Tests
(Peer reviewed; Journal article, 2023)Objective To evaluate the predictive value of biomarkers of inflammation like phagocyte-related S100 proteins and a panel of inflammatory cytokines in order to differentiate the child with acute lymphoblastic leukemia ... -
Inflammatory bowel disease
(Journal article; Peer reviewed, 2015)Scandinavian researchers have contributed to the present understanding of inflammatory bowel disease (IBD). Important epidemiological data and family risk factors have been reported from all the Nordic countries, original ... -
Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19
(Peer reviewed; Journal article, 2022)Introduction: Both public and scientific attention have shifted from the acute COVID-19 illness to the chronic disability experienced by a proportion of COVID-19 convalescents. Post COVID-19 condition, a term used for ...