Browsing Institutt for klinisk og molekylær medisin by Title

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    • Fear of hypoglycaemia and its relation to hypoglycaemia awareness and symptom intensity in Type 1 diabetes 

      Hatle, Håvard; Bjørgaas, Marit Ragnhild Rokne; Rø, Torstein Baade; Olsen, Sandra Elise; Åsvold, Bjørn Olav (Journal article; Peer reviewed, 2018)
      Aims To investigate fear of hypoglycaemia (FoH) in relation to hypoglycaemia awareness, history of severe hypoglycaemia (SH) and hypoglycaemia symptoms in adults with Type 1 diabetes. Methods Questionnaire-based ...

    • Feasibility and accuracy of point-of-care pocket-size ultrasonography performed by medical students 

      Andersen, Garrett Newton; Viset, Annja Torlaug; Mjølstad, Ole Christian; Salvesen, Øyvind; Dalen, Håvard; Haugen, Bjørn Olav (Journal article; Peer reviewed, 2014)
      Background Point-of-care ultrasound performed by clinicians is a useful supplement in the treatment and assessment of patients. We aimed to investigate whether medical students with minimal training were able to successfully ...

    • Feasibility of contrast-enhanced MRI derived textural features to predict overall survival in locally advanced breast cancer. 

      Chronaiou, Ioanna; Giskeødegård, Guro F.; Goa, Pål Erik; Teruel, Jose; Hedayati, Roja; Lundgren, Steinar; Huuse, Else Marie; Pickles, Martin D.; Gibbs, Peter; Sitter, Beathe; Bathen, Tone Frost (Journal article; Peer reviewed, 2019)
      Background The prognosis for women with locally advanced breast cancer (LABC) is poor and there is a need for better treatment stratification. Gray-level co-occurrence matrix (GLCM) texture analysis of magnetic resonance ...

    • Feasibility of early meal detection based on abdominal sound. 

      Kölle, Konstanze; Fougner, Anders Lyngvi; Ellingsen, Reinold; Carlsen, Sven Magnus; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Background In classical approaches for an artificial pancreas, continuous glucose monitoring (CGM) is the only measured variable used for insulin dosing and additional control functions. The CGM values are subject to time ...

    • Feature-based classification of human transcription factors into hypothetical sub-classes related to regulatory function. 

      Ehsani, Rezvan; Bahrami, Shahram; Drabløs, Finn Sverre (Peer reviewed; Journal article, 2016)
      Background Transcription factors are key proteins in the regulation of gene transcription. An important step in this process is the opening of chromatin in order to make genomic regions available for transcription. Data ...

    • Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease 

      Thorsvik, Silje; Damås, Jan Kristian; Granlund, Atle van Beelen; Flo, Trude Helen; Bergh, Kåre; Østvik, Ann Elisabet; Sandvik, Arne Kristian (Journal article; Peer reviewed, 2017)
      Background and Aim Accurate, noninvasive biomarkers are needed to diagnose and monitor inflammatory bowel disease (IBD). Neutrophil gelatinase-associated lipocalin (NGAL), also known as lipocalin 2, is expressed in inflamed ...

    • Feeding Behavior and Body Weight Development:: Lessons from Rats 

      Furnes, Marianne W. (Doktoravhandlinger ved NTNU, 1503-8181; 2008:251, Doctoral thesis, 2008)
      Background and aim Strains of rats in use today are derived almost exclusively from the Norway rat. Common outbred stocks are Wistar, Long-Evans and Sprague-Dawley, which are believed to better mimic the diverse genetics ...

    • Felles referanseområder for antiepileptika 

      Reimers, Arne; Berg, Jon Andsnes; Burns, Margrete Larsen; Landmark, Cecilie Johannessen (Journal article; Peer reviewed, 2017)
      Antiepileptika er grunnsteinen i behandlingen av epilepsi og brukes også ved en rekke andre indikasjoner. Serumkonsentrasjonsmåling av antiepileptika har hatt lang tradisjon som hjelpemiddel i behandling av epilepsi i ...

    • Fetal and perinatal implications of anomalies in the gastrointestinal tract and the abdominal wall 

      Brantberg, Anne (Doktoravhandlinger ved NTNU, 1503-8181; 2007:113, Doctoral thesis, 2007)
      Studien tar for seg tilstandene gastroschise og omfalocele, som er forskjellige former for bukveggsdefekter samt utviklingsavvik som gir forsnevringer på ulike nivå i fordøyelseskanalen: spiserør (øsofagusobstruksjon), ...

    • Fetal growth and birth anthropometrics in metformin exposed offspring born to mothers with PCOS 

      Hjorth-Hansen, Anna; Salvesen, Øyvind; Hanem, Liv Guro Engen; Eggebø, Torbjørn Moe; Salvesen, Kjell Å; Vanky, Eszter; Ødegård, Rønnaug (Journal article; Peer reviewed, 2017)
      Context Metformin is used in an attempt to reduce pregnancy complications associated with polycystic ovary syndrome (PCOS). Little is known about the effect of metformin on fetal development and growth. Objectives To ...

    • Fetal head descent assessed by transabdominal ultrasound: a prospective observational study 

      Kamel, Rasha; Negm, Sherif; Badr, Islam; Kahrs, Birgitte Heiberg; Eggebø, Torbjørn M.; Iversen, Johanne Kolvik von Ely (Peer reviewed; Journal article, 2021)
      Background Detection of copy number variation (CNV) in genes associated with disease is important in genetic diagnostics, and next generation sequencing (NGS) technology provides data that can be used for CNV detection. ...

    • Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia 

      Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M.; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero Olavi; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel; Kere, Juha (Peer reviewed; Journal article, 2020)
      Background Fetal immune tolerance is crucial for pregnancy success. We studied the link between preeclampsia, a severe pregnancy disorder with uncertain pathogenesis, and fetal human leukocyte antigen G (HLA-G) and other ...

    • Fetal molding examined with transperineal ultrasound and associations with position and delivery mode 

      Iversen, Johanne Kolvik; Kahrs, Birgitte Heiberg; Torkildsen, Erik A.; Eggebø, Torbjørn Moe (Journal article; Peer reviewed, 2020)
      Background To accommodate passage through the birth canal, the fetal skull is compressed and reshaped, a phenomenon known as molding. The fetal skull bones are separated by membranous sutures that facilitate compression ...

    • FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis 

      Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2017)
      Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ...

    • Ficolins do not alter host immune responses to lipopolysaccharide-induced inflammation in vivo 

      Genster, Ninette; Østrup, Olga; Schjalm, Camilla; Mollnes, Tom Eirik; Cowland, Jack B.; Garred, Peter (Journal article; Peer reviewed, 2017)
      Ficolins are a family of pattern recognition molecules that are capable of activating the lectin pathway of complement. A limited number of reports have demonstrated a protective role of ficolins in animal models of ...

    • Finding gene regulatory network candidates using the gene expression knowledge base 

      Venkatesan, Aravind; Tripathi, Sushil; Sanz de Galdeano, Alejandro; Blondé, Ward; Lægreid, Astrid; Mironov, Vladimir; Kuiper, Martin (Journal article; Peer reviewed, 2014)
      Background: Network-based approaches for the analysis of large-scale genomics data have become well established. Biological networks provide a knowledge scaffold against which the patterns and dynamics of ?omics? data can ...

    • Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys 

      Eikrem, Øystein Solberg; Walther, Tedd Christian; Flatberg, Arnar; Beisvag, Vidar; Strauss, Philipp; Farstad, Magnus; Beisland, Christian; Koch, Even; Mueller, Thomas F.; Marti, Hans-Peter (Journal article; Peer reviewed, 2018)
      Background Transcriptome analysis is emerging as emerging as a promising tool to enhance precision of diagnosis and monitoring in solid organ transplantation. Clinical progress has however been hampered by the current ...

    • Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases 

      Hinks, A; Bowes, J; Cobb, J; Ainsworth, HC; Marion, MC; Comeau, ME; Sudman, M; Han, B; Becker, ML; Bohnsack, JF; de Bakker, PIW; Haas, JP; Hazen, M; Lovell, DJ; Nigrovic, PA; Nordal, Ellen Berit; Punnaro, M; Rosenberg, AM; Rygg, Marite; Smith, S.L.; Wise, CA; Videm, Vibeke; Wedderburn, LR; Yarwood, A; Yeung, RSM; Prahalad, S; Langefeld, CD; Raychaudhuri, S; Thompson, SD; Thomson, W (Journal article; Peer reviewed, 2017)
      Objectives Juvenile idiopathic arthritis (JIA) is a heterogeneous group of diseases, comprising seven categories. Genetic data could potentially be used to help redefine JIA categories and improve the current classification ...

    • Finnes det medikamenter som kan forbedre den kognitive funksjonen hos friske individer?: En litteraturstudie av potensielt kognisjonsfremmende medikamenter 

      Hiorth, Jonas; Saso, Anders (Master thesis, 2010)
      Bakgrunn. Det er stor faglig og kommersiell interesse rundt medikamenter som kan virke kognisjonsfremmende hos friske individer. Det finnes flere medikamenter som i dag brukes i behandling av ulike sykdomstilstander, og ...

    • The first mitochondrial 5-methylcytosine map in a non-model teleost (Oreochromis niloticus) reveals extensive strand-specific and non-CpG methylation 

      Nedoluzhko, Artem; Mjelle, Robin; Renström, Maria; Skjærven, Kaja Helvik; Piferrer, Francesc; Fernandes, Jorge Manuel de Oliveira (Peer reviewed; Journal article, 2021)
      DNA methylation is one of the main epigenetic mechanisms that regulate gene expression in a manner that depends on the genomic context and varies considerably across taxa. This DNA modification was first found in nuclear ...