Blar i Publikasjoner fra Cristin - St. Olavs hospital på tittel
Viser treff 1096-1115 av 1459
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Prevalence of adverse childhood experiences and their co-occurrence in a large population of adolescents: a Young HUNT 3 study
(Peer reviewed; Journal article, 2022)Abstract Purpose Studies of adverse childhood experiences (ACEs) undertaken at the time of adolescence in the general population are not common. The aim of this study was to determine the prevalence and co-occurrence of ... -
Prevalence of temporomandibular disorder in children and adolescents with juvenile idiopathic arthritis – a Norwegian cross- sectional multicentre study
(Peer reviewed; Journal article, 2020)Background Children and adolescents with juvenile idiopathic arthritis (JIA) may suffer pain from temporomandibular disorder (TMD). Still, routines for the assessment of temporomandibular joint (TMJ) pain in health and ... -
Prevalence, risk factors, and type of sleep apnea in patients with paroxysmal atrial fibrillation
(Peer reviewed; Journal article, 2019)Background Recent studies have suggested an association between sleep apnea (SA) and atrial fibrillation (AF). We aimed to study the prevalence, characteristics, risk factors and type of sleep apnea (SA) in ablation ... -
Preventing type 2 diabetes, overweight and obesity in the Norwegian primary healthcare: a longitudinal design with 60 months follow-up results and a cross-sectional design with comparison of dropouts versus completers
(Peer reviewed; Journal article, 2022)Objectives Studies have demonstrated that it is possible to prevent type 2 diabetes for individuals at high risk, but long-term results in the primary healthcare are limited and high dropout rates have been reported. Design ... -
Primary versus recurrent surgery for glioblastoma-a prospective cohort study
(Peer reviewed; Journal article, 2020)Background: There is currently limited evidence for surgery in recurrent glioblastoma (GBM). Our aim was to compare primary and recurrent surgeries, regarding changes in perioperative, generic health-related quality of ... -
PRL-3 induces a positive signaling circuit between glycolysis and activation of STAT1/2
(Peer reviewed; Journal article, 2021)Multiple myeloma (MM) is an incurable hematologic malignancy resulting from the clonal expansion of plasma cells. MM cells are interacting with components of the bone marrow microenvironment such as cytokines to survive ... -
The pro-tumorigenic cytokine IL-32 has a high turnover in multiple myeloma cells due to proteolysis regulated by oxygen-sensing cysteine dioxygenase and deubiquitinating enzymes
(Peer reviewed; Journal article, 2023)IL-32 is a pro-inflammatory cytokine expressed by several types of cancer cells and immune cells. Currently, no treatment targeting IL-32 is available, and its intracellular and exosomal localization make IL-32 less ... -
The prognostic impact of depressive symptoms on all-cause mortality in individuals with abdominal aortic aneurysm and in the general population. A population-based prospective HUNT study in Norway
(Peer reviewed; Journal article, 2022)Background Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease but the high mortality rate is linked to high age and comorbidity pattern. Depression is associated with increased mortality in the general ... -
Prognostic markers for survival in patients with oligodendroglial tumors; a single-institution review of 214 cases
(Peer reviewed; Journal article, 2017)Background: In the 2016 WHO classification, the diagnosis of oligodendroglioma has been restricted to IDH mutated, 1p19q codeleted tumors (IDHmut-codel). IDHmut oligoastrocytoma is now classified either as oligodendroglioma ... -
Prognostic Validation of the NINDS Common Data Elements for the Radiologic Reporting of Acute Traumatic Brain Injuries: A CENTER-TBI Study
(Peer reviewed; Journal article, 2020)The aim of this study is to investigate the prognostic value of using the National Institute of Neurological Disorders and Stroke (NINDS) standardized imaging-based pathoanatomic descriptors for the evaluation and reporting ... -
Prognostic value of baseline functional status measures and geriatric screening in vulnerable older patients with metastatic colorectal cancer receiving palliative chemotherapy – The randomized NORDIC9-study
(Peer reviewed; Journal article, 2022)Introduction - Appropriate patient selection based on functional status is crucial when considering older adults for palliative chemotherapy. This pre-planned analysis of the randomized NORDIC9-study explored the prognostic ... -
Prolonged migraine aura: New insights from a prospective diary-aided study
(Journal article; Peer reviewed, 2018)Background: There is limited literature on prolonged aura (PA - defined as an aura including at least one symptom for > 1 h and < 7d), and there are no prospective studies. The aim of this study is to characterize prospectively ... -
Prospects of returning to work after lumbar spine surgery for patients considering disability pension: A nationwide study based on data from the Norwegian Registry for Spine Surgery
(Peer reviewed; Journal article, 2023)Objectives To assess the odds for not returning to work (non-RTW) 1 year after treatment among patients who had applied for or were planning to apply for disability pension (DP-applicant) prior to an operation for degenerative ... -
Protect us from ourselves: Balancing the parental instinct of saving
(Peer reviewed; Journal article, 2019)Background: Neonatologists, legal experts and ethicists extensively discuss the ethical challenges of decision-making when a child is born at the limit of viability. The voices of parents are less heard in this discussion. ... -
Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia
(Peer reviewed; Journal article, 2017)Plasma cell leukemia is a rare and aggressive plasma cell neoplasm that may either originate de novo (primary PCL) or by leukemic transformation of multiple myeloma (MM) to secondary PCL (sPCL). The prognosis of sPCL is ... -
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases
(Peer reviewed; Journal article, 2022)Proteome-wide Mendelian randomization (MR) shows value in prioritizing drug targets in Europeans but with limited evidence in other ancestries. Here, we present a multi-ancestry proteome-wide MR analysis based on ... -
Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
(Peer reviewed; Journal article, 2021)Background Studies have reported that the combination of some prothrombotic genotypes and overt cancer yields a synergistic effect on VTE risk. Whether individual prothrombotic genotypes or number of risk alleles in a ... -
A protocol for the development and validation of a virtual reality-based clinical test of social cognition
(Peer reviewed; Journal article, 2023)Background Impairments in social cognition are common after traumatic brain injury (TBI) and may have severe negative consequences for patients and their families. Most tests of social cognition have limited ecological ... -
Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P)
(Peer reviewed; Journal article, 2024)Background Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs ...