• Ageing, functioning patterns and their environmental determinants in the spinal cord injury (SCI) population: A comparative analysis across eleven European countries implementing the International Spinal Cord Injury Community Survey 

  Sabariego, Carla; Ehrmann, Cristina; Bickenbach, Jerome; Barzallo, Diana Pacheco; Leiulfsrud, Annelie; Strøm, Vegard; Osterthun, Rutger; Tederko, Piotr; Seijas, Vanessa; Eriks-Hoogland, Inge; Le Fort, Marc; Viejo, Miguel Angel Gonzalez; Bökel, Andrea; Popa, Daiana; Dionyssiotis, Yannis; Baricich, Alessio; Juocevičius, Alvydas; Amico, Paolo; Stucki, Gerold (Peer reviewed; Journal article, 2023)

  Background As the European population with Spinal Cord Injury (SCI) is expected to become older, a better understanding of ageing with SCI using functioning, the health indicator used to model healthy ageing trajectories, ...

• Motor outcomes in individuals born small for gestational age at term: a systematic review 

  Taiar, Hoda; Benum, Silje Dahl; Aakvik, Kristina Anna Djupvik; Evensen, Kari Anne Indredavik (Journal article; Peer reviewed, 2024)

  Background: Being born small for gestational age (SGA) is a risk factor for motor difficulties. Previous reviews exploring this topic are mostly focused on children born preterm. We aimed to review the literature to determine ...

• Health-related quality of life in children born preterm at school age: the mediating role of social support and maternal stress 

  Martínez-Shaw, Melissa Liher; Evensen, Kari Anne Indredavik; Melero, Sandra; Sánchez-Sandoval, Yolanda (Peer reviewed; Journal article, 2024)

  Research on health-related quality of life (HRQoL) of school-aged children born preterm (< 37 weeks of gestational age) is scarce and there are few studies examining the relationship with medical and family factors. The ...

• RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork 

  Hayran , Abdul Baset ; Liabakk, Nina-Beate; Aas, Per Arne; Kusnierczyk, Anna; Vågbø, Cathrine Broberg; Sarno, Antonio; Iveland, Tobias Solli; Chawla, Konika; Zahn, Astrid; DiNoia, Javier M; Slupphaug, Geir; Kavli, Bodil Merete (Peer reviewed; Journal article, 2023)

  Activation-induced cytidine deaminase (AID) interacts with replication protein A (RPA), the major ssDNA-binding protein, to promote deamination of cytosine to uracil in transcribed immunoglobulin (Ig) genes. Uracil-DNA ...

• A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors 

  Swift, Imogen J.; Rademakers, Rosa; Finch, NiCole; Baker, Matt; Ghidoni, Roberta; Benussi, Luisa; Binetti, Giuliano; Rossi, Giacomina; Synofzik, Matthis; Wilke, Carlo; Mengel, David; Graff, Caroline; Takada, Leonel T.; Sánchez-Valle, Raquel; Antonell, Anna; Galimberti, Daniela; Fenoglio, Chiara; Serpente, Maria; Arcaro, Marina; Schreiber, Stefanie; Vielhaber, Stefan; Arndt, Philipp; Santana, Isabel; Almeida, Maria Rosario; Moreno, Fermín; Barandiaran, Myriam; Gabilondo, Alazne; Stubert, Johannes; Gómez-Tortosa, Estrella; Agüero, Pablo; Sainz, M. José; Gohda, Tomohito; Murakoshi, Maki; Kamei, Nozomu; Kittel-Schneider, Sarah; Reif, Andreas; Weigl, Johannes; Jian, Jinlong; Liu, Chuanju; Serrero, Ginette; Greither, Thomas; Theil, Gerit; Lohmann, Ebba; Gazzina, Stefano; Bagnoli, Silvia; Coppola, Giovanni; Bruni, Amalia; Quante, Mirja; Kiess, Wieland; Hiemisch, Andreas; Jurkutat, Anne; Block, Matthew S.; Carlson, Aaron M.; Bråthen, Geir; Sando, Sigrid Botne; Grøntvedt, Gøril Rolfseng; Lauridsen, Camilla; Heslegrave, Amanda; Heller, Carolin; Abel, Emily; Gómez-Núñez, Alba; Puey, Roger; Arighi, Andrea; Rotondo, Enmanuela; Jiskoot, Lize C.; Meeter, Lieke H. H.; Durães, João; Lima, Marisa; Tábuas-Pereira, Miguel; Lemos, João; Boeve, Bradley; Petersen, Ronald C.; Dickson, Dennis W.; Graff-Radford, Neill R.; LeBer, Isabelle; Sellami, Leila; Lamari, Foudil; Clot, Fabienne; Borroni, Barbara; Cantoni, Valentina; Rivolta, Jasmine; Lleó, Alberto; Fortea, Juan; Alcolea, Daniel; Illán-Gala, Ignacio; Andres-Cerezo, Lucie; Van Damme, Philip; Clarimon, Jordi; Steinacker, Petra; Feneberg, Emily; Otto, Markus; van der Ende, Emma L.; van Swieten, John C.; Seelaar, Harro; Zetterberg, Henrik; Sogorb-Esteve, Aitana; Rohrer, Jonathan D. (Peer reviewed; Journal article, 2024)

  Background Pathogenic heterozygous mutations in the progranulin gene (GRN) are a key cause of frontotemporal dementia (FTD), leading to significantly reduced biofluid concentrations of the progranulin protein (PGRN). This ...

• A qualitative study examining the health system's response to COVID-19 in Sierra Leone 

  Stone, Hana; Bailey, Emma; Wurie, Haja; Leather, Andrew J M; Davies, Justine I.; Bolkan, Håkon Angell; Sevalie, Stephen; Youkee, Daniel; Parmar, Divya (Peer reviewed; Journal article, 2024)

  The paper examines the health system’s response to COVID-19 in Sierra Leone. It aims to explore how the pandemic affected service delivery, health workers, patient access to services, leadership, and governance. It also ...

• Intelligence and executive function are associated with age at insult, time post-insult, and disability following chronic pediatric acquired brain injury 

  Brandt, Anne Elisabeth; Rø, Torstein Baade; Finnanger, Torun Gangaune; Hypher, Ruth Elizabeth; Lien, Espen August; Lund, Bendik; Catroppa, Cathy; Andersson, Stein; Risnes, Kari; Stubberud, Jan Egil (Peer reviewed; Journal article, 2023)

  Background: Pediatric acquired brain injury (pABI) profoundly affects cognitive functions, encompassing IQ and executive functions (EFs). Particularly, young age at insult may lead to persistent and debilitating deficits, ...

• Physical activity and cognitive function in adults born very preterm or with very low birth weight–an individual participant data meta-analysis 

  Aakvik, Kristina Anna Djupvik; Benum, Silje Dahl; Tikanmäki, Marjaana; Hovi, Petteri; Räikkönen, Katri; Harris, Sarah L.; Woodward, Lianne J.; Darlow, Brian A.; Indredavik, Marit Sæbø; Lydersen, Stian; Mork, Paul Jarle; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2024)

  Objective Individuals born very preterm (<32 weeks of gestation) or with very low birthweight (<1500g) have lower cognitive function compared with term-born peers. Furthermore, some studies suggest that they are less ...

• Comparison of Magnetic Resonance Imaging-Based Risk Calculators to Predict Prostate Cancer Risk 

  Patel, Hiten; Remmers, Sebastiaan; Ellis, Jeffrey L.; Li, Eric V.; Roobol, Monique J.; Fang, Andrew M.; Davik, Petter; Rais-Bahrami, Soroush; Murphy, Adam B.; Ross, Ashley E.; Gupta, Gopal N. (Peer reviewed; Journal article, 2024)

  Importance Magnetic resonance imaging (MRI)–based risk calculators can replace or augment traditional prostate cancer (PCa) risk prediction tools. However, few data are available comparing performance of different MRI-based ...

• Covalent PARylation of DNA base excision repair proteins regulates DNA demethylation 

  Schwarz, Simon D.; Xu, Jianming; Gunasekera, Kapila; Schürmann, David; Vågbø, Cathrine Broberg; Ferrari, Elena; Slupphaug, Geir; Hottiger, Michael O.; Schär, Primo; Steinacher, Roland (Peer reviewed; Journal article, 2024)

  The intracellular ATP-ribosyltransferases PARP1 and PARP2, contribute to DNA base excision repair (BER) and DNA demethylation and have been implicated in epigenetic programming in early mammalian development. Recently, ...

• Does the ypTNM-stage adequately predict long-term survival rates in gastric cancer patients receiving neoadjuvant chemotherapy followed by radical resection? 

  Sandø, Alina Desiree; Grønbech, Jon Erik; Bringeland, Erling Audun (Peer reviewed; Journal article, 2023)

  Background Following neoadjuvant chemotherapy (NAC) for resectable gastric cancer, the prognostic adequacy of the UICC staging system needs to be investigated. In particular to explore whether the ypTNM curves for ...

• Esophageal cancers missed at upper endoscopy in Central Norway 2004 to 2021 – A population-based study 

  Straum, Synne; Rekstad, Lars Cato; Fossmark, Reidar; Wollan, Karoline (Journal article; Peer reviewed, 2024)

  Introduction: The incidence of esophageal cancers is increasing in many Western countries and the rate of missed esophageal cancers (MEC) at upper endoscopy is of concern. We aimed to calculate the MEC rate and identify ...

• Serum vitamin D, blood pressure and hypertension risk in the HUNT study using observational and Mendelian randomization approaches 

  Jiang, Lin; Sun, Yi-Qian; Dénos, Marion Nicole Marie; Brumpton, Ben Michael; Chen, Yue; Malmo, Vegard; Sanderson, Eleanor; Mai, Xiao-Mei (Journal article; Peer reviewed, 2024)

  Limited studies have triangulated the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and systolic blood pressure (SBP), diastolic blood pressure (DBP) or hypertension risk utilizing both observational and ...

• Resilience and Adaptability in Paracetamol Supply Chains: A Systems Perspective on COVID-19 Challenges and Responses in Ethiopia 

  Melaku, Tsegaye; Mekonnen, Zeleke; Tucho, Gudina Terefe; Viana, Joe; Årdal, Christine Oline; Jahre, Marianne (Journal article; Peer reviewed, 2025)

  Background: The COVID-19 pandemic exposed vulnerabilities in global supply chains, including those for essential medicines like paracetamol. This study aimed to assess the resilience and adaptability of Ethiopia’s paracetamol ...

• Associations between maternal and offspring glucose metabolism: a 9-year follow-up of a randomised controlled trial 

  Nyen, Sigrid Langfeldt; Stunes, Astrid Kamilla; Evensen, Kari Anne Indredavik; Børsting, Torunn; Syversen, Unni; Salvesen, Kjell Åsmund Blix; Mørkved, Siv; Stafne, Signe Nilssen (Journal article; Peer reviewed, 2024)

  Introduction: There is increasing evidence that the in utero environment affects the health and disease risk of offspring throughout their lives. The long-term effect of maternal hyperglycaemia on offspring glucose metabolism ...

• Development and validation of a prognostic model to predict birth weight: individual participant data meta-analysis 

  Allotey, John; Archer, Lucinda; Snell, Kym I.E.; Coomar, Dyuti; Massé, Jacques; Sletner, Line; Wolf, Hans; Daskalakis, George; Saito, Shigeru; Ganzevoort, Wessel; Ohkuchi, Akihide; Mistry, Hema; Farrar, Diane; Mone, Fionnuala; Zhang, Jun; Seed, Paul T.; Teede, Helena; da Silva Costa, Fabricio; Souka, Athena P.; Smuk, Melanie; Ferrazzani, Sergio; Salvi, Silvia; Prefumo, Federico; Gabbay-Benziv, Rinat; Nagata, Chie; Takeda, Satoru; Sequeira, Evan; Lapaire, Olav; Cecatti, Jose Guilherme; Morris, Rachel Katherine; Baschat, Ahmet A.; Salvesen, Kjell Åsmund Blix; Smits, Luc; Anggraini, Dewi; Rumbold, Alice R.; Gelder, Marleen Van; Coomarasamy, Arri; Kingdom, John; Heinonen, Seppo; Khalil, Asma; Goffinet, François; Haqnawaz, Sadia; Zamora, Javier; Riley, Richard D.; Thangaratinam, Shakila (Peer reviewed; Journal article, 2024)

  Objective To predict birth weight at various potential gestational ages of delivery based on data routinely available at the first antenatal visit. Design Individual participant data meta-analysis. Data sources ...

• Effects of Low-Dose Glucagon on Subcutaneous Insulin Absorption in Pigs 

  Teigen, Ingrid Anna; Åm, Marte Kierulf; Riaz, Misbah; Christiansen, Sverre Christian; Carlsen, Sven Magnus (Peer reviewed; Journal article, 2024)

  Background Slow insulin absorption prevents the development of a fully automated artificial pancreas with subcutaneous insulin delivery. Objective We have hypothesized that glucagon could be used as a vasodilator to ...

• Geriatric impairments are prevalent and predictive of survival in older patients with cancer receiving radiotherapy: a prospective observational study 

  Eriksen, Guro Falk; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Kirkhus, Lene; Kirkevold, Øyvind; Hjelstuen, Anne Kristine; Jordhøy, Marit Slaaen (Peer reviewed; Journal article, 2021)

  Background: A systematic assessment of problems that are frequent in older age (geriatric assessment [GA]) provides prognostic information for patients undergoing cancer surgery and systemic cancer treatment. We aimed to ...

• Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease 

  Domenighetti, Cloé; Sugier, Pierre-Emmanuel; Sreelatha, Ashwin Ashok Kumar; Schulte, Claudia; Grover, Sandeep; Mohamed, Oceáne; Portugal, Berta; May, Patrick; Bobbili, Dheeraj R.; Radivojkov-Blagojevic, Milena; Lichtner, Peter; Singleton, Andrew B.; Hernandez, Dena G.; Edsall, Connor; Mellick, George D.; Zimprich, Alexander; Pirker, Walter; Rogaeva, Ekaterina; Lang, Anthony E.; Koks, Sulev; Taba, Pille; Lesage, Suzanne; Brice, Alexis; Corvol, Jean-Christophe; Chartier-Harlin, Marie-Christine; Mutez, Eugénie; Brockmann, Kathrin; Deutschländer, Angela B.; Hadjigeorgiou, Georges M.; Dardiotis, Efthimos; Stefanis, Leonidas; Simitsi, Athina Maria; Valente, Enza Maria; Petrucci, Simona; Duga, Stefano; Straniero, Letizia; Zecchinelli, Anna; Pezzoli, Gianni; Brighina, Laura; Ferrarese, Carlo; Annesi, Grazia; Quattrone, Andrea; Gagliardi, Monica; Matsuo, Hirotaka; Kawamura, Yusuke; Hattori, Nobutaka; Nishioka, Kenya; Chung, Sun Ju; Kim, Yun Joong; Kolber, Pierre; Van De Warrenburg, Bart Pc; Bloem, Bastiaan R.; Aasly, Jan; Toft, Mathias; Pihlstrøm, Lasse; Guedes, Leonor Correia; Ferreira, Joaquim J.; Bardien, Soraya; Carr, Jonathan; Tolosa, Eduardo; Ezquerra, Mario; Pastor, Pau; Diez-Fairen, Monica; Wirdefeldt, Karin; Pedersen, Nancy L.; Ran, Caroline; Belin, Andrea C.; Puschmann, Andreas; Hellberg, Clara; Clarke, Carl E.; Morrison, Karen E.; Tan, Manuela; Krainc, Dimitri; Burbulla, Lena F.; Farrer, Matt J.; Krüger, Rejko; Gasser, Thomas; Sharma, Manu; Elbaz, Alexis (Peer reviewed; Journal article, 2022)

  Background:Previous studies showed that lifestyle behaviors (cigarette smoking, alcohol, coffee) are inversely associated with Parkinson’s disease (PD). The prodromal phase of PD raises the possibility that these associations ...

• Mediating Factors in the Association of Maternal Educational Level with Pregnancy Outcomes: A Mendelian Randomization Study 

  Rogne, Tormod; Gill, Dipender; Liew, Zeyan; Shi, Xiaoting; Stensrud, Vilde; Nilsen, Tom Ivar Lund; Burgess, Stephen (Peer reviewed; Journal article, 2024)

  IMPORTANCE Lower educational attainment is associated with increased risk of adverse pregnancy outcomes, but it is unclear which pathways mediate this association. OBJECTIVE To investigate the association between educational ...

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