• Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis 

      Allotey, John; Snell, Kym I.E.; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; von Dadelszen, Peter; Dodds, Julie; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid S.; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony O.; Ramírez, Javier A.; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, AA; Seed, PT; Prefumo, F; da Silva Costa, F; Groen, H; Audibert, F; Masse, J; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, C; Rumbold, Alice R.; Heinonen, Seppo; Askie, LM; Smits, LJ; Vinter, CA; Magnus, Per; Kajantie, Eero Olavi; Villa, PM; Jenum, Anne Karen; Andersen, LB; Norman, JE; Ohkuchi, A; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala M.; Galindo, Alberto; Herraiz, Ignacio; Carbillon, , Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Teede, Helena J.; Browne, Joyce L; Moons, Karel G.M.; Riley, Richard D; Thangaratinam, Shakila (Peer reviewed; Journal article, 2020)
      Background: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. Objectives: To assess the performance of existing pre-eclampsia ...
    • Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1-results of the Canadian model in the Nordic cohort. 

      Rypdal, Veronika Gjertsen; Guzman, Jaime; Henrey, A; Loughin, T; Glerup, Mia; Arnstad, Ellen Dalen; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan M.; Herlin, Troels; Fasth, Anders; Berntson, Lillemor; Rypdal, Martin wibe; Nordal, Ellen Berit (Journal article; Peer reviewed, 2019)
      Background Models to predict disease course and long-term outcome based on clinical characteristics at disease onset may guide early treatment strategies in juvenile idiopathic arthritis (JIA). Before a prediction model ...
    • A validity study of the rapid emergency Triage and treatment system for children 

      Ødegård, Siv Steinsmo; Tran, Thuy; Næss-Pleym, Lars E.; Risnes, Kari; Døllner, Henrik (Peer reviewed; Journal article, 2021)
      Background: The Scandinavian Rapid Emergency Triage and Treatment System-pediatric (RETTS-p) is a reliable triage system that includes both assessment of vital parameters and a systematic approach to history and symptoms. ...
    • Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition 

      Brumpton, Ben Michael; Fritsche, Lars; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria Nastase; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E.; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; van't Hooft, Ferdinand M.; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2019)
      PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, ...
    • Variations in the Circle of Willis in a large population sample using 3D TOF angiography: The Tromsø Study 

      Hindenes, Lars Bakke; Håberg, Asta; Johnsen, Liv-Hege; Mathiesen, Ellisiv B.; David, Robben; Vangberg, Torgil Riise (Peer reviewed; Journal article, 2020)
      The main arteries that supply blood to the brain originate from the Circle of Willis (CoW). The CoW exhibits considerable anatomical variations which may have clinical importance, but the variability is insufficiently ...
    • Vascular risk factor control and adherence to secondary preventive medication after ischemic stroke 

      Gynnild, Mari Nordbø; Aakerøy, Rachel; Spigset, Olav; Askim, Torunn; Beyer, Mona Kristiansen; Ihle-Hansen, Hege; Munthe-Kaas, Ragnhild; Knapskog, Anne Brita; Lydersen, Stian; Næss, Halvor; Røsstad, Tove Garåsen; Seljeseth, Yngve Müller; Thingstad, Pernille; Saltvedt, Ingvild; Ellekjær, Hanne (Peer reviewed; Journal article, 2020)
      Background Studies regarding adequacy of secondary stroke prevention are limited. We report medication adherence, risk factor control and factors influencing vascular risk profile following ischaemic stroke. Methods A ...
    • Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents - A DTI study 

      Lindqvist, Susanne; Skranes, Jon; Eikenes, Live; Haraldseth, Olav; Vik, Torstein; Brubakk, Ann-Mari; Vangberg, Torgil (Peer reviewed; Journal article, 2011)
      Premature birth is associated with visual impairments, due to both cerebral and ocular pathology. This study examined the relationship between cerebral white matter microstructure, evaluated by diffusion tensor imaging ...
    • Vitamin D status and risk of type 2 diabetes in the Norwegian HUNT cohort study: Does family history or genetic predisposition modify the association? 

      Denos, Marion; Mai, Xiao-Mei; Åsvold, Bjørn Olav; Sørgjerd, Elin Pettersen; Chen, Yue; Sun, Yi-Qian (Peer reviewed; Journal article, 2021)
      Introduction We sought to investigate the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and the risk of type 2 diabetes mellitus (T2DM) in adults who participated in the Trøndelag Health Study (HUNT), and ...
    • White matter hyperintensities and headache: A population-based imaging study (HUNT MRI) 

      Honningsvåg, Lasse-Marius; Håberg, Asta; Hagen, Knut; Kvistad, Kjell Arne; Stovner, Lars Jacob; Linde, Mattias (Journal article; Peer reviewed, 2018)
      Objective To examine the relationship between white matter hyperintensities and headache. Methods White matter hyperintensities burden was assessed semi-quantitatively using Fazekas and Scheltens scales, and by manual ...
    • Why do myeloma patients have bone disease? A historical perspective. 

      Børset, Magne; Sundan, Anders; Waage, Anders; Standal, Therese (Peer reviewed; Journal article, 2019)
      The question of how myeloma cells cause destruction of skeletal tissue has interested scientists for many years, and knowledge in this field has developed in parallel with the understanding of physiological bone remodeling. ...
    • Will (or can) people pay for headache care in a poor country? 

      Lampl, Christian; Steiner, Timothy J.; Mueller, T; Mirvelashvili, E; Djibuti, M; Kukava, M; Dzagnidze, A; Jensen, Rigmor; Stovner, Lars Jacob; Katzarava, Zaza (Journal article; Peer reviewed, 2012)
      We asked whether attempts to introduce headache services in poor countries would be futile on grounds of cost and unsustainability. Using data from a population-based survey in the Republic of Georgia, an exemplary poor ...
    • Within family Mendelian randomization studies 

      Davies, Neil M.; Howe, Laurence; Brumpton, Ben Michael; Havdahl, Alexandra; Evans, David M.; Smith, George Davey (Peer reviewed; Journal article, 2019)
      Mendelian randomization (MR) is increasingly used to make causal inferences in a wide range of fields, from drug development to etiologic studies. Causal inference in MR is possible because of the process of genetic ...
    • Work environment factors and respiratory complaints in Norwegian cooks 

      Svedahl, Sindre Rabben; Hilt, Bjørn; Svendsen, Kristin V Hirsch (Peer reviewed; Journal article, 2019)
      Purpose Norwegian cooks exhibit relatively high mortality, particularly from respiratory diseases. Both occupational hazards and lifestyle factors have been suggested as possible explanations. Negative health effects from ...
    • Work-Related Mental Fatigue, Physical Activity and Risk of Insomnia Symptoms: Longitudinal Data from the Norwegian HUNT Study 

      Skarpsno, Eivind S.; Nilsen, Tom Ivar Lund; Sand, Trond; Hagen, Knut; Mork, Paul Jarle (Journal article; Peer reviewed, 2019)
      Objective/Background: To examine the prospective association between work-related mental fatigue and risk of insomnia symptoms, and if leisure time physical activity modifies this association. Participants: A total of ...