Now showing items 1-20 of 501

    • 1-year follow-up of 920 hip and knee arthroplasty patients after implementing fast-track: Good outcomes in a Norwegian university hospital 

      Winther, Siri Bjørgen; Foss, Olav A.; Wik, Tina Strømdal; Davis, Shawn Patric; Engdal, Monika; Jessen, Vigleik; Husby, Otto Schnell (Journal article; Peer reviewed, 2015)
      Background — Fast–track has become a well–known concept resulting in improved patient satisfaction and postoperative results. Concerns have been raised about whether increased efficiency could compromise safety, and whether ...
    • 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...
    • 2-hydroxyglutarate as a magnetic resonance biomarker for glioma subtyping 

      Esmaeili, Morteza; Vettukattil, Riyas M; Bathen, Tone Frost (Journal article; Peer reviewed, 2013)
      Mutations in the isocitrate dehydrogenase (IDH) genes are frequently found in gliomas and in a fraction of acute myeloid leukemia patients. This results in the production of an oncometabolite, 2-hydroxyglutarate (2-HG). ...
    • A 36-month follow-up of decline in activities of daily living in individuals receiving domiciliary care 

      Helvik, Anne-Sofie; Høgset, Lisbeth Dyrendal; Bergh, Sverre; Saltyte Benth, Jurate; Kirkevold, Øyvind; Selbæk, Geir (Journal article; Peer reviewed, 2015)
      Background There have been few studies of how personal and instrumental activities of daily living (P-ADL and I-ADL) develop over time in older people receiving domiciliary care. This study aimed at assessing variables ...
    • A European multicentre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts 

      Hayes, A; Nguyen, Dung; Andersson, Monique; Antón, Andres; Bailly, Jean-Luc; Beard, Stuart; Benschop, Kimberley; Berginc, Natasa; Blomqvist, Soile; Cunningham, Emma; Davis, D; Dembinski, Jennifer Lynn; Diedrich, Sabine; Dudman, Susanne Marie Rogne Gjeruldsen; Dyrdak, R; Eltringham, G. J. A.; Gonzales-Goggia, S; Gunson, R; Howson-Wells, H. C.; Jääskeläinen, A. J.; López-Labrador, F. Xavier; Maier, M.; Majumdar, M.; Midgley, S.; Mirand, A.; Morley, U.; Nordbø, Svein Arne; Oikarinen, S; Osman, H; Papa, A; Pellegrinelli, L; Piralla, A; Rabella, N; Richter, J; Smith, M; Söderlund Strand, A; Templeton, K; Vipond, B; Vuorinen, T; Williams, C; Wollants, E; Zakikhany, K; Fischer, T. K.; Harvala, H; Simmonds, P (Journal article; Peer reviewed, 2019)
      Polymerase chain reaction (PCR) detection has become the gold standard for diagnosis and typing of enterovirus (EV) and human parechovirus (HPeV) infections. Its effectiveness depends critically on using the appropriate ...
    • A meta-analysis of constraint-induced movement therapy after stroke 

      Thrane, Gyrd; Friborg, Oddgeir; Anke, Audny; Indredavik, Bent (Journal article; Peer reviewed, 2014)
      Objective: To evaluate the effect of constraint-induced movement therapy in adult stroke patients and to examine the impact of time since stroke and various treatment modalities. Data sources: PubMed, EMBASE, Cochrane and ...
    • A much valued tool that also brings ethical dilemmas-a qualitative study of Norwegian midwives' experiences and views on the role of obstetric ultrasound 

      Åhman, Annika; Edvardsson, Kristina; Fagerli, Anita; Darj, Elisabeth; Holmlund, Sofia; Small, Rhonda; Mogren, Ingrid (Journal article; Peer reviewed, 2019)
      Background: Midwives are the main providers of routine antenatal care services including the routine ultrasound examination in Norway. The ultrasound examination can be perceived by expectant parents not only as a medical ...
    • A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training 

      Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas; Croci, Ilaria; Taylor, Jenna L; Gajanand, Trishan; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Pattyn, Nele; Howden, Erin J.; Keating, Shelley E.; Bye, Anja; Stensvold, Dorthe; Wisløff, Ulrik; Papadimitriou, Ioannis; Yan, Xu; Bishop, David J.; Eynon, Nir; Coombes, Jeff S. (Journal article; Peer reviewed, 2019)
      There is heterogeneity in the observed www.frontiersin.orgO2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability). The aim of this study ...
    • A new acoustic coupling fluid with ability to reduce ultrasound imaging artefacts in brain tumour surgery - a phase I study 

      Unsgård, Geirmund; Sagberg, Lisa Millgård; Muller, Sebastien; Selbekk, Tormod (Journal article; Peer reviewed, 2019)
      Background Anovel acoustic coupling fluid (ACF), with the potential to reduce surgically induced image artefacts during intraoperative ultrasound imaging in brain tumour surgery, has been evaluated with respect to image ...
    • A property-based analysis of human transcription factors 

      Bahrami, Shahram; Ehsani, Rezvan; Drabløs, Finn (Journal article; Peer reviewed, 2015)
      Background Transcription factors are essential proteins for regulating gene expression. This regulation depends upon specific features of the transcription factors, including how they interact with DNA, how they interact ...
    • A randomized study on migration of the Spectron EF and the Charnley flanged 40 cemented femoral components using radiostereometric analysis at 2 years 

      Kadar, Thomas; Hallan, Geir; Aamodt, Arild; Indrekvam, Kari; Badawy, Mona; Havelin, Leif Ivar; Stokke, Terje; Haugan, Kristin; Espehaug, Birgitte; Furnes, Ove (Journal article; Peer reviewed, 2011)
      Background and purpose We performed a randomized study to determine the migration patterns of the Spectron EF femoral stem and to compare them with those of the Charnley stem, which is regarded by many as the gold standard ...
    • Absent exercise-induced improvements in fat oxidation in women with polycystic ovary syndrome after high-intensity interval training 

      Lionett, Sofie Buurgaard; Kiel, Ida Almenning; Røsbjørgen, Ragnhild; Lydersen, Stian; Larsen, Steen; Moholdt, Trine (Peer reviewed; Journal article, 2021)
      Background: Polycystic ovary syndrome (PCOS) and metabolic inflexibility are linked to insulin resistance, and women with PCOS appear to be metabolic inflexible in the rested, insulin-stimulated state. Exercise training ...
    • Accuracy and Complication Rates of External Ventricular Drain Placement With Twist Drill and Bolt System Versus Standard Trephine and Tunnelation: A Retrospective Population-Based Study 

      Mansoor, Nadia Mauland; Madsbu, Mattis Aleksander; Mansoor, Nina M.; Trønnes, Andreas; Fredriksli, Oddrun; Salvesen, Øyvind; Jakola, Asgeir S; Solheim, Ole; Gulati, Sasha (Peer reviewed; Journal article, 2020)
      Background: An external ventricular drain (EVD) is typically indicated in the presence of hydrocephalus and increased intracranial pressure (ICP). Procedural challenges have prompted the development of different methods ...
    • Accuracy of breast cancer lesion classification using intravoxel incoherent motion diffusion-weighted imaging is improved by the inclusion of global or local prior knowledge with bayesian methods 

      Vidic, Igor; Jerome, Neil Peter; Bathen, Tone Frost; Goa, Pål Erik; While, Peter Thomas (Journal article; Peer reviewed, 2019)
      Background Diffusion‐weighted MRI (DWI) has potential to noninvasively characterize breast cancer lesions; models such as intravoxel incoherent motion (IVIM) provide pseudodiffusion parameters that reflect tissue perfusion, ...
    • Activins as Dual Specificity TGF-β Family Molecules: SMAD-Activation via Activin- and BMP-Type 1 Receptors 

      Olsen, Oddrun Elise; Hella, Hanne; Elsaadi, Samah; Jacobi, Carsten; Martinez-Hackert, Erik; Holien, Toril (Peer reviewed; Journal article, 2020)
      Activins belong to the transforming growth factor (TGF)-β family of multifunctional cytokines and signal via the activin receptors ALK4 or ALK7 to activate the SMAD2/3 pathway. In some cases, activins also signal via the ...
    • Admissions and surgery as indicators of hospital functions in Sierra Leone during the west-African Ebola outbreak 

      Bolkan, Håkon Angell; van Duinen, Aalke Johan; Samai, Mohammed; Bash-Taqi, Donald Alpha; Gassama, Ibarahim; Waalewijn, Bart; Wibe, Arne; von Schreeb, Johan (Journal article; Peer reviewed, 2018)
      Background In an attempt to assess the effects of the Ebola viral disease (EVD) on hospital functions in Sierra Leone, the aim of this study was to evaluate changes in provisions of surgery and non-Ebola admissions during ...
    • Adverse events of exercise therapy in randomised controlled trials: A systematic review and meta-analysis 

      Niemeijer, Andre; Lund, Hans; Stafne, Signe Nilssen; Ipsen, Thomas; Goldschmidt, Cathrine Luhaäär; Jørgensen, Claus Thomas; Juhl, Carsten B. (Journal article; Peer reviewed, 2019)
      Objective To evaluate the relative risk (RR) of serious and non-serious adverse events in patients treated with exercise therapy compared with those in a non-exercising control group. Design Systematic review and ...
    • Adverse events with fatal outcome associated with alemtuzumab treatment in multiple sclerosis 

      Holmøy, Trygve; Fevang, Børre; Olsen, David Benee; Spigset, Olav; Bø, Lars (Journal article; Peer reviewed, 2019)
      Objective Sporadic fatal adverse events have been reported during treatment of multiple sclerosis with alemtuzumab. To provide a systematic overview, we searched the centralized European Medicines Agency database of ...
    • Age-of-onset information helps identify 76 genetic variants associated with allergic disease 

      Ferreira, Manuel A R; Vonk, Judith M.; Baurecht, Hansjörg; Marenholz, Ingo; Tian, Chao; Hoffman, Joshua D.; Helmer, Quinta; Tillander, Annika; Ullemar, Vilhelmina; Lu, Yi; Grosche, Sarah; Ruschendorf, Franz; Granell, Raquel; Brumpton, Ben Michael; Fritsche, Lars; Bhatta, Laxmi; Gabrielsen, Maiken Elvestad; Nielsen, Jonas Bille; Zhou, Wei; Hveem, Kristian; Langhammer, Arnulf; Holmen, Oddgeir; Løset, Mari; Abecasis, Goncalo; Willer, Cristen J.; Emami, Nima C.; Cavazos, Taylor B.; Witte, John S.; Szwajda, Agnieszka; 23andMe Research Team, ,; collaborators of SHARE study, ,; Hinds, David A.; Hubner, Norbert; Weidinger, Stephan; Magnusson, Patrik KE; Jorgenson, Eric; Karlsson, Robert; Paternoster, Lavinia; Boomsma, Dorret I.; Almqvist, Catarina; Lee, Young-Ae; Koppelman, Gerard H.; Esparza-Gordillo, Jorge; Hummel, Oliver; Hottenga, Jouke-Jan; Willemsen, Gonneke; Rodríguez, Elke; Hotze, Melanie; Franke, Andre; Matheson, Melanie C.; Dharmage, Shyamali Chandrika; Arnold, Andreas; Homuth, Georg; Schmidt, Carsten O; Thompson, Philip J.; Martin, Nicholas G; Duffy, David L.; Novak, Natalija; Schulz, Holger; Karrasch, Stefan; Gieger, Christian; Strauch, Konstantin; Melles, Ronald B (Peer reviewed; Journal article, 2020)
      Risk factors that contribute to inter-individual differences in the age-of-onset of allergic diseases are poorly understood. The aim of this study was to identify genetic risk variants associated with the age at which ...
    • AI-driven attenuation correction for brain PET/MRI: Clinical evaluation of a dementia cohort and importance of the training group size 

      Ladefoged, Claes Nøhr; Hansen, Adam Espe; Henriksen, Otto Mølby; Bruun, Frederik Jager; Eikenes, Live; Øen, Silje Kjærnes; Karlberg, Anna Maria; Højgaard, Liselotte; Law, Ian; Andersen, Flemming Littrup (Peer reviewed; Journal article, 2020)
      Introduction Robust and reliable attenuation correction (AC) is a prerequisite for accurate quantification of activity concentration. In combined PET/MRI, AC is challenged by the lack of bone signal in the MRI from which ...