Now showing items 472-491 of 495

    • Ultrapure Wood Nanocellulose - Assessments of Coagulation and Initial Inflammation Potential 

      Nordli, Henriette R.; Pukstad, Brita; Chinga-Carrasco, Gary; Rokstad, Anne Mari (Journal article; Peer reviewed, 2019)
      Using a lepirudin-based human whole blood model, we evaluated the initial inflammatory and coagulation responses of dense and porous ultrapure (<50 endotoxin units/grams) cellulose nanofibrils (CNF), of carboxylated grade. ...
    • Ultrasound-Mediated Delivery of Chemotherapy into the Transgenic Adenocarcinoma of the Mouse Prostate Model 

      Fagerland, Stein-Martin Tilrum; Berg, Sigrid; Hill, Deborah Katherine; Snipstad, Sofie; Sulheim, Einar; Hyldbakk, Astrid; Kim, Jana; Davies, Catharina de Lange (Peer reviewed; Journal article, 2020)
      Ultrasound (US) in combination with microbubbles (MB) has had promising results in improving delivery of chemotherapeutic agents. However, most studies are done in immunodeficient mice with xenografted tumors. We used two ...
    • Uncertainty quantification and sensitivity analysis for computational FFR estimation in stable coronary artery disease 

      Fossan, Fredrik Eikeland; Sturdy, Jacob; Muller, Lucas Omar; Strand, Andreas; Bråten, Anders Tjellaug; Jørgensen, Arve; Wiseth, Rune; Hellevik, Leif Rune (Journal article; Peer reviewed, 2018)
      Purpose The main objectives of this study are to validate a reduced-order model for the estimation of the fractional flow reserve (FFR) index based on blood flow simulations that incorporate clinical imaging and ...
    • Understanding the relationship between cognitive performance and function in daily life after traumatic brain injury 

      Wilson, Lindsay; Horton, Lindsay; Kunzmann, Kevin; Sahakian, Barbara J.; Newcombe, Virginia; Stamatakis, E; Steinbuechel, Nicole; Cunitz, Kathrin; Covic, Amra; Maas, Andrew; van Praag, Dominigue; Menon, David; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo (Peer reviewed; Journal article, 2020)
      Objective: Cognitive impairment is a key cause of disability after traumatic brain injury (TBI) but relationships with overall functioning in daily life are often modest. The aim is to examine cognition at different levels ...
    • Unsatisfactory risk factor control and high rate of new cardiovascular events in patients with myocardial infarction and prior coronary artery disease 

      Jortveit, Jarle; Halvorsen, Sigrun; Kaldal, Anete; Pripp, Are Hugo; Govatsmark, Ragna Elise Støre; Langørgen, Jørund (Peer reviewed; Journal article, 2019)
      Background: Patients with established coronary artery disease (CAD) have an increased risk of new cardiovascular events. An underuse of secondary preventive drugs has been observed, and many patients may not attain the ...
    • Urban–Rural Differences in Hip Fracture Mortality: A Nationwide NOREPOS Study 

      Solbakken, Siri Marie; Magnus, Jeanette H.; Meyer, Haakon E; Dahl, Cecilie; Stigum, Hein; Søgaard, Anne-Johanne; Holvik, Kristin; Tell, Grethe S.; Emaus, Nina; Forsmo, Siri; Gjesdal, Clara Gram; Schei, Berit; Vestergaard, Peter; Omsland, Tone Kristin (Journal article; Peer reviewed, 2019)
      Higher hip fracture incidence in urban than in rural areas has been demonstrated, but urban–rural differences in posthip fracture mortality have been less investigated, and the results are disparate. Hence, the aims of the ...
    • Use and validity of child neurodevelopment outcome measures in studies on prenatal exposure to psychotropic and analgesic medications – A systematic review 

      Andersen, Sarah Hjorth; Bromley, Rebecca; Ystrøm, Eivind; Lupattelli, Angela; Spigset, Olav; Nordeng, Hedvig Marie Egeland (Journal article; Peer reviewed, 2019)
      In recent years there has been increased attention to child neurodevelopment in studies on medication safety in pregnancy. Neurodevelopment is a multifactorial outcome that can be assessed by various assessors, using ...
    • Using the CustusX toolkit to create an image guided bronchoscopy application: Fraxinus 

      Bakeng, Janne Beate Lervik; Hofstad, Erlend Fagertun; Solberg, Ole Vegard; Eiesland, Jon Wostryck; Tangen, Geir Arne; Amundsen, Tore; Langø, Thomas; Reinertsen, Ingerid; Selbekk, Tormod; Leira, Håkon Olav (Journal article; Peer reviewed, 2019)
      Purpose The aim of this paper is to show how a specialized planning and guidance application called Fraxinus, can be built on top of the CustusX platform (www.custusx.org), which is an open source image-guided intervention ...
    • Utility of T2-weighted MRI texture analysis in assessment of peripheral zone prostate cancer aggressiveness: a single-arm, multicenter study 

      Nketiah, Gabriel Addio; Elschot, Mattijs; Scheenen, Tom W.J.; Maas, Marnix C.; Bathen, Tone Frost; Selnæs, Kirsten Margrete (Peer reviewed; Journal article, 2021)
      T2-weighted (T2W) MRI provides high spatial resolution and tissue-specific contrast, but it is predominantly used for qualitative evaluation of prostate anatomy and anomalies. This retrospective multicenter study evaluated ...
    • Uveitis in Juvenile Idiopathic Arthritis 18-Year Outcome in the Population-based Nordic Cohort Study 

      Rypdal, Veronika Gjertsen; Glerup, Mia; Songstad, Nils Thomas; Herlin, Troels; Rygg, Marite; Nordal, Ellen Berit (Peer reviewed; Journal article, 2020)
      Purpose To assess the long-term outcome of uveitis in juvenile idiopathic arthritis (JIA). Design Population-based, multicenter, prospective JIA cohort, with a cross-sectional assessment of JIA-associated uveitis ...
    • Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis 

      Allotey, John; Snell, Kym I.E.; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; von Dadelszen, Peter; Dodds, Julie; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid S.; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony O.; Ramírez, Javier A.; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, AA; Seed, PT; Prefumo, F; da Silva Costa, F; Groen, H; Audibert, F; Masse, J; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, C; Rumbold, Alice R.; Heinonen, Seppo; Askie, LM; Smits, LJ; Vinter, CA; Magnus, Per; Kajantie, Eero Olavi; Villa, PM; Jenum, Anne Karen; Andersen, LB; Norman, JE; Ohkuchi, A; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala M.; Galindo, Alberto; Herraiz, Ignacio; Carbillon, , Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Teede, Helena J.; Browne, Joyce L; Moons, Karel G.M.; Riley, Richard D; Thangaratinam, Shakila (Peer reviewed; Journal article, 2020)
      Background: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. Objectives: To assess the performance of existing pre-eclampsia ...
    • Validation of prediction models of severe disease course and non-achievement of remission in juvenile idiopathic arthritis: part 1-results of the Canadian model in the Nordic cohort. 

      Rypdal, Veronika Gjertsen; Guzman, Jaime; Henrey, A; Loughin, T; Glerup, Mia; Arnstad, Ellen Dalen; Aalto, Kristiina; Rygg, Marite; Nielsen, Susan M.; Herlin, Troels; Fasth, Anders; Berntson, Lillemor; Rypdal, Martin wibe; Nordal, Ellen Berit (Journal article; Peer reviewed, 2019)
      Background Models to predict disease course and long-term outcome based on clinical characteristics at disease onset may guide early treatment strategies in juvenile idiopathic arthritis (JIA). Before a prediction model ...
    • A validity study of the rapid emergency Triage and treatment system for children 

      Ødegård, Siv Steinsmo; Tran, Thuy; Næss-Pleym, Lars E.; Risnes, Kari; Døllner, Henrik (Peer reviewed; Journal article, 2021)
      Background: The Scandinavian Rapid Emergency Triage and Treatment System-pediatric (RETTS-p) is a reliable triage system that includes both assessment of vital parameters and a systematic approach to history and symptoms. ...
    • Variation in serum PCSK9 (proprotein convertase subtilisin/kexin type 9), cardiovascular disease risk, and an investigation of potential unanticipated effects of PCSK9 inhibition 

      Brumpton, Ben Michael; Fritsche, Lars; Zheng, Jie; Nielsen, Jonas Bille; Mannila, Maria Nastase; Surakka, Ida; Rasheed, Humaira; Vie, Gunnhild Åberge; Graham, Sarah E.; Gabrielsen, Maiken Elvestad; Laugsand, Lars Erik; Aukrust, Pål; Vatten, Lars Johan; Damås, Jan Kristian; Ueland, Thor; Janszky, Imre; Zwart, John-Anker; van't Hooft, Ferdinand M.; Seidah, Nabil Georges; Hveem, Kristian; Willer, Cristen; Smith, George Davey; Åsvold, Bjørn Olav (Peer reviewed; Journal article, 2019)
      PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce serum LDL (low-density lipoprotein) cholesterol (LDL-C) by increasing uptake in the liver. Although some long-term trials have evaluated their safety, ...
    • Variations in the Circle of Willis in a large population sample using 3D TOF angiography: The Tromsø Study 

      Hindenes, Lars Bakke; Håberg, Asta; Johnsen, Liv-Hege; Mathiesen, Ellisiv B.; David, Robben; Vangberg, Torgil Riise (Peer reviewed; Journal article, 2020)
      The main arteries that supply blood to the brain originate from the Circle of Willis (CoW). The CoW exhibits considerable anatomical variations which may have clinical importance, but the variability is insufficiently ...
    • Vascular risk factor control and adherence to secondary preventive medication after ischemic stroke 

      Gynnild, Mari Nordbø; Aakerøy, Rachel; Spigset, Olav; Askim, Torunn; Beyer, Mona Kristiansen; Ihle-Hansen, Hege; Munthe-Kaas, Ragnhild; Knapskog, Anne Brita; Lydersen, Stian; Næss, Halvor; Røsstad, Tove Garåsen; Seljeseth, Yngve Müller; Thingstad, Pernille; Saltvedt, Ingvild; Ellekjær, Hanne (Peer reviewed; Journal article, 2020)
      Background Studies regarding adequacy of secondary stroke prevention are limited. We report medication adherence, risk factor control and factors influencing vascular risk profile following ischaemic stroke. Methods A ...
    • Visual function and white matter microstructure in very-low-birth-weight (VLBW) adolescents - A DTI study 

      Lindqvist, Susanne; Skranes, Jon; Eikenes, Live; Haraldseth, Olav; Vik, Torstein; Brubakk, Ann-Mari; Vangberg, Torgil (Peer reviewed; Journal article, 2011)
      Premature birth is associated with visual impairments, due to both cerebral and ocular pathology. This study examined the relationship between cerebral white matter microstructure, evaluated by diffusion tensor imaging ...
    • Vitamin D status and risk of type 2 diabetes in the Norwegian HUNT cohort study: Does family history or genetic predisposition modify the association? 

      Denos, Marion; Mai, Xiao-Mei; Åsvold, Bjørn Olav; Sørgjerd, Elin Pettersen; Chen, Yue; Sun, Yi-Qian (Peer reviewed; Journal article, 2021)
      Introduction We sought to investigate the relationship between serum 25-hydroxyvitamin D (25(OH)D) level and the risk of type 2 diabetes mellitus (T2DM) in adults who participated in the Trøndelag Health Study (HUNT), and ...
    • White matter hyperintensities and headache: A population-based imaging study (HUNT MRI) 

      Honningsvåg, Lasse-Marius; Håberg, Asta; Hagen, Knut; Kvistad, Kjell Arne; Stovner, Lars Jacob; Linde, Mattias (Journal article; Peer reviewed, 2018)
      Objective To examine the relationship between white matter hyperintensities and headache. Methods White matter hyperintensities burden was assessed semi-quantitatively using Fazekas and Scheltens scales, and by manual ...
    • Why do myeloma patients have bone disease? A historical perspective. 

      Børset, Magne; Sundan, Anders; Waage, Anders; Standal, Therese (Peer reviewed; Journal article, 2019)
      The question of how myeloma cells cause destruction of skeletal tissue has interested scientists for many years, and knowledge in this field has developed in parallel with the understanding of physiological bone remodeling. ...